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<?xml version="1.0"?><feed xmlns="http://www.w3.org/2005/Atom" xml:lang="en"> <id>https://humanlove.stream/api.php?hidebots=1&urlversion=1&days=7&limit=50&action=feedrecentchanges&feedformat=atom</id> <title>Human's Love - Recent changes [en]</title> <link rel="self" type="application/atom+xml" href="https://humanlove.stream/api.php?hidebots=1&urlversion=1&days=7&limit=50&action=feedrecentchanges&feedformat=atom"/> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/Special:RecentChanges"/> <updated>2025-06-03T10:23:04Z</updated> <subtitle>Track the most recent changes to the wiki in this feed.</subtitle> <generator>MediaWiki 1.30.0</generator> <entry> <id>https://humanlove.stream/wiki/User:Dalrympleweeks4527</id> <title>User:Dalrympleweeks4527</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Dalrympleweeks4527"/> <updated>2025-06-03T10:23:03Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Dalrympleweeks4527&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Dalrympleweeks4527 (page does not exist)"><bdi>Dalrympleweeks4527</bdi></a> was created</p></summary> <author><name>Dalrympleweeks4527</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Allnormaldispersion_dissipative_soliton_fibers_laser_employing_an_offsetsplicing_gradedindexmultimodefiberbased_saturable_absorber&diff=3298567&oldid=0</id> <title>Allnormaldispersion dissipative soliton fibers laser employing an offsetsplicing gradedindexmultimodefiberbased saturable absorber</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Allnormaldispersion_dissipative_soliton_fibers_laser_employing_an_offsetsplicing_gradedindexmultimodefiberbased_saturable_absorber&diff=3298567&oldid=0"/> <updated>2025-06-03T10:22:55Z</updated> <summary type="html"><p>Created page with &quot;The results of pharmacokinetic studies in human volunteers further demonstrated that, compared to a marketed MX tablets, MX-SNELCs provided a higher Cmax, Tmax, and AUC and a...&quot;</p><p><b>New page</b></p><div>The results of pharmacokinetic studies in human volunteers further demonstrated that, compared to a marketed MX tablets, MX-SNELCs provided a higher Cmax, Tmax, and AUC and a relatively greater bioavailability of 152.97 %. The successfully developed MX-SNELCs were found to be a better alternative than the conventional tablet dosage form, thus indicating their potential for further development in a clinically acceptable strategy for managing periodontal pain.We present a combined study by quasielastic neutron scattering (QENS), dielectric and mechanical spectroscopy, calorimetry and wide-angle X-ray diffraction on single-chain nano-particles (SCNPs), using the corresponding linear precursor chains as reference, to elucidate the impact of internal bonds involving bulky cross-links on the properties of polymer melts. Internal cross-links do not appreciably alter local properties and fast dynamics. This is the case of the average inter-molecular distances, the β-relaxation and the extent of the atomic displacements at timescales faster than some picoseconds. Contrarily, the α-relaxation is slowed down with respect to the linear precursor, as detected by DSC, dielectric spectroscopy and QENS. QENS has also resolved broader response functions and stronger deviations from Gaussian behavior in the SCNPs melt, hinting at additional heterogeneities. The rheological properties are also clearly affected by internal cross-links. We discuss these results together with those previously reported on the deuterated counterpart samples and on SCNPs obtained through a different synthesis route to discern the effect of the nature of the cross-links on the modification of the diverse properties of the melts.The shear-induced and cellulose-nanofiber nucleated crystallization of two novel aliphatic-aromatic copolyesters is outlined due to its significance for the in situ generation of biodegradable nanocomposites, which require the crystallization of nanofibrous sheared inclusions at higher temperatures. The shear-induced non-isothermal crystallization of two copolyesters, namely, poly(butylene adipate-co-succinate-co-glutarate-co-terephthalate) (PBASGT) and poly(butylene adipate-co-terephthalate) (PBAT), was studied following a light depolarization technique. To have a deep insight into the process, the effects of the shear rate, shear time, shearing temperature and cooling rate on the initiation, kinetics, growth and termination of crystals were investigated. Films of 60 μm were subjected to various shear rates (100-800 s-1) for different time intervals during cooling. The effects of the shearing time and increasing the shear rate were found to be an elevated crystallization temperature, increased nucleation density, reduced growth size of lamella stacks and decreased crystallization time. Due to the boosted nucleation sites, the nuclei impinged with each other quickly and growth was hindered. The effect of the cooling rate was more significant at lower shear rates. Shearing the samples at lower temperatures, but still above the nominal melting point, further shifted the non-isothermal crystallization to higher temperatures. As a result of cellulose nanofibers' presence, the crystallization of PBAT, analyzed by DSC, was shifted to higher temperatures.The contribution of Spanish scientists to the rheology involved in polymer processing during the last 25 years is investigated. It is shown that the performed research covers, at different levels, all industrial polymeric materials thermoplastics, thermosets, adhesives, biopolymers, composites and nanocomposites, and polymer modified bitumen. Therefore, the rheological behaviour of these materials in processing methods such as extrusion, injection moulding, additive manufacturing, and others is discussed, based on the literature results. A detailed view of the most outstanding achievements, based on the rheological criteria of the authors, is offered.Electrospun polyvinyl alcohol (PVA) nanofiber fabric was modified by Cibacron Blue F3GA (CB) to enhance the affinity of the fabric. Batch experiments were performed to study the nanofiber fabric's bovine hemoglobin (BHb) adsorption capacity at different protein concentrations before and after modification. The maximum BHb adsorption capacity of the modified nanofiber fabric was 686 mg/g, which was much larger than the 58 mg/g of the original fabric. After that, the effect of feed concentration and permeation rate on the dynamic adsorption behaviors for BHb of the nanofiber fabric was investigated. The pH impact on BHb and bovine serum albumin (BSA) adsorption was examined by static adsorption experiments of single protein solutions. [https://www.selleckchem.com/products/isoproterenol-sulfate-dihydrate.html Neuronal Signaling agonist] The selective separation experiments of the BHb-BSA binary solution were carried out at the optimal pH value, and a high selectivity factor of 5.45 for BHb was achieved. Finally, the reusability of the nanofiber fabric was examined using three adsorption-elution cycle tests. This research demonstrated the potential of the CB-modified PVA nanofiber fabric in protein adsorption and selective separation.The development of novel polymer-based materials opens up possibilities for several novel applications, such as advanced wound dressings, bioinks for 3D biofabrication, drug delivery systems, etc. The aim of this study was to evaluate the viability of vascular and intestinal epithelial cells on different polymers as a selection procedure for more advanced cell-polymer applications. In addition, possible correlations between increased cell viability and material properties were investigated. Twelve polymers were selected, and thin films were prepared by dissolution and spin coating on silicon wafers. The prepared thin films were structurally characterized by Fourier transform infrared spectroscopy, atomic force microscopy, and goniometry. Their biocompatibility was determined using two epithelial cell lines (human umbilical vein endothelial cells and human intestinal epithelial cells), assessing the metabolic activity, cell density, and morphology. The tested cell lines showed different preferences regarding the culture substrate. No clear correlation was found between viability and individual substrate characteristics, suggesting that complex synergistic effects may play an important role in substrate design. These results show that a systematic approach is required to compare the biocompatibility of simple cell culture substrates as well as more complex applications (e.g., bioinks).</div></summary> <author><name>Spongeclaus9</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Natural_synthesis_of_cerium_oxide_nanoparticles_utilizing_Acorus_calamus_acquire_and_their_antibiofilm_exercise_versus_bacterial_pathoenic_agents&diff=3298566&oldid=0</id> <title>Natural synthesis of cerium oxide nanoparticles utilizing Acorus calamus acquire and their antibiofilm exercise versus bacterial pathoenic agents</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Natural_synthesis_of_cerium_oxide_nanoparticles_utilizing_Acorus_calamus_acquire_and_their_antibiofilm_exercise_versus_bacterial_pathoenic_agents&diff=3298566&oldid=0"/> <updated>2025-06-03T10:22:51Z</updated> <summary type="html"><p>Created page with &quot;A mass spectrometric study of secondary ions emitted from droplet surfaces by MeV-energy heavy ion impact was performed to investigate fast-ion-induced molecular reaction proc...&quot;</p><p><b>New page</b></p><div>A mass spectrometric study of secondary ions emitted from droplet surfaces by MeV-energy heavy ion impact was performed to investigate fast-ion-induced molecular reaction processes on liquid surfaces. Herein, a new coincidence technique was developed between secondary ions and scattered projectile ions at a small forward angle. The advantages of this technique were demonstrated by measurement of the collision between 4-MeV C3+ and ethanol droplets. Secondary ion emission probabilities were obtained directly from the coincidence data. Notably, this technique enabled positive fragment ions that had not been identified in previous measurements to be observed by suppressing the strong background originating from gas-phase molecules more than 104-fold. H+, H3O+, C2H5+, and C2H5O+ were found to be produced as major positive fragment ions, in addition to minor fragments H2+, C2H3+, and CH2OH+. Production of these ions suggests that competition between rapid hydrogen ion emission from multiply ionized states and intermolecular proton transfer accompanied by fragmentation through protonated ethanol occurs after fast heavy-ion collisions. Clarification of the positive fragment ions also revealed the characteristic features of negative ions. Negative ions were realized to exhibit higher degrees of fragmentation and reactivity compared with positive ions. Furthermore, the energy loss by forward-scattered ions during droplet penetration was used to evaluate the target thickness at a submicron level. Variations in secondary ion yield, mass distribution, and kinetic energies depending on the penetration length were observed below 1 µm. These results highlight the unknown mechanism of these &quot;submicron effects&quot; observed in secondary ion emission processes as a new phenomenon.In modern physics, the entanglement between quantum states is a well-established phenomenon. Going one step forward, one can conjecture the likely existence of an entanglement between excitations of one-particle quantum states. Working with a density matrix that is well defined within the polarization propagator formalism, together with information theory, we found that the quantum origin of, at least, few molecular response properties can be described by the entanglement between two pairs of virtual excitations of molecular orbitals (MOs). With our model, we are able to bring new insights into the electronic mechanisms that are behind the transmission, and communication, of the effects of a given perturbation to the whole electronic system described by the Hamiltonian of an unperturbed quantum system. With our entanglement model, we analyzed the electronic origin of the Karplus rule of nuclear magnetic resonance spectroscopy, a well-known empirical phenomenon, and found that this rule is straightforwardly related to the behavior of entangled MO excitations. The model compound used to show it is the H2O2 molecule.The diffusion Monte Carlo (DMC), auxiliary field quantum Monte Carlo (AFQMC), and equation-of-motion coupled cluster (EOM-CC) methods are used to calculate the electron binding energy (EBE) of the non-valence anion state of a model (H2O)4 cluster. Two geometries are considered, one at which the anion is unbound and the other at which it is bound in the Hartree-Fock (HF) approximation. It is demonstrated that DMC calculations can recover from the use of a HF trial wave function that has collapsed onto a discretized continuum solution, although larger EBEs are obtained when using a trial wave function for the anion that provides a more realistic description of the charge distribution and, hence, of the nodal surface. For the geometry at which the cluster has a non-valence correlation-bound anion, both the inclusion of triples in the EOM-CC method and the inclusion of supplemental diffuse d functions in the basis set are important. DMC calculations with suitable trial wave functions give EBE values in good agreement with our best estimate EOM-CC result. AFQMC using a trial wave function for the anion with a realistic electron density gives a value of the EBE nearly identical to the EOM-CC result when using the same basis set. For the geometry at which the anion is bound in the HF approximation, the inclusion of triple excitations in the EOM-CC calculations is much less important. [https://www.selleckchem.com/products/pixantrone-maleate.html Pixantrone in vitro] The best estimate EOM-CC EBE value is in good agreement with the results of DMC calculations with appropriate trial wave functions.We propose a general formalism for polarizable embedding models that can be applied to either continuum or atomistic polarizable models. After deriving such a formalism for both variational and non-variational models, we address the problem of coupling two polarizable models among themselves and to a quantum mechanical (QM) description in the spirit of multiscale quantum chemistry. We discuss general, model-independent coupling hypotheses and derive coupled polarization equations for all combinations of variational and non-variational models and discuss the embedding contributions to the analytical derivatives of the energy, with a particular focus on the elements of the Fock or Kohn-Sham matrix. We apply the general formalism to the derivation of the working equations for a three-layered, fully polarizable QM/MM/continuum strategy using the non-variational atomic multipole optimized energetics for biomolecular applications polarizable force field and the domain decomposition conductor-like screening model.We study the generation of electronic ring currents in the presence of nonadiabatic coupling using circularly polarized light. For this, we introduce a solvable model consisting of an electron and a nucleus rotating around a common center and subject to their mutual Coulomb interaction. The simplicity of the model brings to the forefront the non-trivial properties of electronic ring currents in the presence of coupling to the nuclear coordinates and enables the characterization of various limiting situations transparently. Employing this model, we show that vibronic coupling effects play a crucial role even when a single E degenerate eigenstate of the system supports the current. The maximum current of a degenerate eigenstate depends on the strength of the nonadiabatic interactions. In the limit of large nuclear to electronic masses, in which the Born-Oppenheimer approximation becomes exact, constant ring currents and time-averaged oscillatory currents necessarily vanish.</div></summary> <author><name>Desirethrill8</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Boyerlyon4702</id> <title>User:Boyerlyon4702</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Boyerlyon4702"/> <updated>2025-06-03T10:22:47Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Boyerlyon4702&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Boyerlyon4702 (page does not exist)"><bdi>Boyerlyon4702</bdi></a> was created</p></summary> <author><name>Boyerlyon4702</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:An99newscom</id> <title>User:An99newscom</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:An99newscom"/> <updated>2025-06-03T10:22:45Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:An99newscom&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:An99newscom (page does not exist)"><bdi>An99newscom</bdi></a> was created</p></summary> <author><name>An99newscom</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=High_temperature_digesting_improved_the_particular_digestibility_involving_phosphorus_throughout_soy_bean_expeller_canola_meal_and_canola_expeller_given_to_growing_pigs&diff=3298565&oldid=0</id> <title>High temperature digesting improved the particular digestibility involving phosphorus throughout soy bean expeller canola meal and canola expeller given to growing pigs</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=High_temperature_digesting_improved_the_particular_digestibility_involving_phosphorus_throughout_soy_bean_expeller_canola_meal_and_canola_expeller_given_to_growing_pigs&diff=3298565&oldid=0"/> <updated>2025-06-03T10:22:45Z</updated> <summary type="html"><p>Created page with &quot;In this review, we summarized the most recent advances concerning the critical roles of SENP3 in normal physiological and pathological conditions as well as the potential clin...&quot;</p><p><b>New page</b></p><div>In this review, we summarized the most recent advances concerning the critical roles of SENP3 in normal physiological and pathological conditions as well as the potential clinical implications in various diseases. Targeting SENP3 alone or in combination with current therapies might provide powerful targeted therapeutic strategies for the treatment of these diseases.Glucocerebrosides are sphingolipid components of cell membranes that intervene in numerous cell biological processes and signaling pathways and that deregulation is implicated in human diseases such as Gaucher disease and Parkinson's disease. In the present study, we conducted a systematic review using document co-citation analysis, clustering and visualization tools to explore the trends and knowledge structure of glucocerebrosides research as indexed in the Science Citation Index Expanded database (1956-present). A co-citation network of 5,324 publications related to glucocerebrosides was constructed. The analysis of emerging categories and keywords suggested a growth of research related to neurosciences over the last decade. We identified ten major areas of research (e.g., clusters) that developed over time, from the oldest (i.e., on glucocerebrosidase protein or molecular analysis of the GBA gene) to the most recent ones (i.e., on drug resistance in cancer, pharmacological chaperones, or Parkinson's disease). We provided for each cluster the most cited publications and a description of their intellectual content. We moreover identified emerging trends in glucocerebrosides research by detecting the surges in the rate of publication citations in the most recent years. In conclusion, this study helps to apprehend the most significant lines of research on glucocerebrosides. This should strengthen the connections between scientific communities studying glycosphingolipids to facilitate advances, especially for the most recent researches on cancer drug resistance and Parkinson's disease.&lt;br /&gt;&lt;br /&gt; Dynamic cerebral autoregulation (dCA) in acute ischemic stroke is probably compromised. Although the characteristics of dCA in different types of stroke have been largely investigated, dCA in embolic stroke of undetermined source (ESUS) remains poorly understood. In this group, we aimed to elucidate the characteristics of dCA and their relevance to clinical outcomes.&lt;br /&gt;&lt;br /&gt; The study enrolled 77 ESUS patients and 50 controls. [https://www.selleckchem.com/products/cc-99677.html Gamcemetinib] Bilateral cerebral blood flow velocities (CBFV) of middle cerebral arteries and arterial blood pressure were simultaneously recorded using a transcranial Doppler combined with a servo-controlled finger plethysmograph. Transfer function analysis was used to obtain dCA parameters including phase, gain, coherence at very low frequency (VLF) and low frequency (LF), and the rate of recovery (RoRc) of CBFV. A multivariable logistic regression model was established to explore the relationship between dCA and clinical outcomes.&lt;br /&gt;&lt;br /&gt; Gain at VLF and LF, phase at LF, and RoRc of CBFV in bilateral hemispheres of the ESUS group were consistently worse than those of the control group (all &lt;br /&gt;&lt;br /&gt; &amp;lt; 0.001). Bilateral RoRc of CBFV was significantly higher in patients with favorable outcomes than in those with unfavorable outcomes (stroke hemisphere &lt;br /&gt;&lt;br /&gt; &amp;lt; 0.001; non-stroke hemisphere, &lt;br /&gt;&lt;br /&gt; = 0.029). Rate of recovery of CBFV in stroke hemisphere &amp;gt;13.3%/s was an independent predictor of favorable clinical outcomes (adjusted odds ratio = 30.95, 95% CI 5.33-179.81, &lt;br /&gt;&lt;br /&gt; &amp;lt; 0.001).&lt;br /&gt;&lt;br /&gt; Dynamic cerebral autoregulation was relatively impaired in both stroke and non-stroke hemispheres in ESUS patients, and functioning dCA after ESUS may indicate favorable clinical outcomes.&lt;br /&gt;&lt;br /&gt;Dynamic cerebral autoregulation was relatively impaired in both stroke and non-stroke hemispheres in ESUS patients, and functioning dCA after ESUS may indicate favorable clinical outcomes.&lt;br /&gt;&lt;br /&gt; The underlying mechanisms by which diabetes and dyslipidemia contribute to diabetic nephropathy (DN) are not fully understood. In this study, we aimed to investigate the role of high glucose (HG) on intracellular cholesterol accumulation in glomerular endothelial cells (GEnCs) and its potential mechanism.&lt;br /&gt;&lt;br /&gt; Oil red O staining, RT-qPCR, Western blotting, and immunocytofluorescence analyses were used to determine cholesterol accumulation and the expressions of LXRs and ABCA1 in GEnCs under high cholesterol (HC) and/or HG conditions, and the effect of these treatments was compared to that of low glucose without adding cholesterol. LncRNA microarrays were used to identify a long non-coding RNA (LncRNA OR13C9), of which levels increased in cells treated with the LXR agonist, GW3965. Fluorescence &lt;br /&gt;&lt;br /&gt; hybridization (FISH) was conducted to confirm subcellular localization of LncOR13C9 and a bioinformatics analysis was used to identify competing endogenous RNA (ceRNA) regulatory networks between LncOR13C9 and microRNhe interaction of LncOR13C9 with miR-23a-5p.&lt;br /&gt;&lt;br /&gt; Overall, our study identified the LXRs/LncOR13C9/miR23A-5p/ABCA1 regulatory network in GEnCs, which may be helpful to better understand the effect of HG on cholesterol accumulation in GEnCs under cholesterol load and to explore new therapeutic tools for the management of DN patients.&lt;br /&gt;&lt;br /&gt;Overall, our study identified the LXRs/LncOR13C9/miR23A-5p/ABCA1 regulatory network in GEnCs, which may be helpful to better understand the effect of HG on cholesterol accumulation in GEnCs under cholesterol load and to explore new therapeutic tools for the management of DN patients.Myocardial ischemia-reperfusion (MI/R) injury is characterized by iron deposition and reactive oxygen species production, which can induce ferroptosis. Ferroptosis has also been proposed to promote cardiomyocyte death. The current study sought to define the mechanism governing cardiomyocyte death in MI/R injury. An animal model of MI/R was established by ligation and perfusion of the left anterior descending coronary artery, and a cellular model of IR was constructed in cardiomyocytes. ChIP assay was then conducted to determine the interaction among USP22, SIRT1, p53, and SLC7A11. Loss- and gain-of-function assays were also conducted to determine the in vivo and in vitro roles of USP22, SIRT1, and SLC7A11. The infarct size and pathological changes of myocardial tissue were observed using TCC and hematoxylin-eosin staining, and the levels of cardiac function- and myocardial injury-related factors of rats were determined. Cardiomyocyte viability and apoptosis were evaluated in vitro, followed by detection of ferroptosis-related indicators (glutathione (GSH), reactive oxygen species, lipid peroxidation, and iron accumulation).</div></summary> <author><name>Aprilvalue97</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Mclaughlinstougaard3457</id> <title>User:Mclaughlinstougaard3457</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Mclaughlinstougaard3457"/> <updated>2025-06-03T10:22:45Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Mclaughlinstougaard3457&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Mclaughlinstougaard3457 (page does not exist)"><bdi>Mclaughlinstougaard3457</bdi></a> was created</p></summary> <author><name>Mclaughlinstougaard3457</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Getting_Inside_Single_Member_Llc_Tax_Problem&diff=3298564&oldid=3295310</id> <title>Getting Inside Single Member Llc Tax Problem</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Getting_Inside_Single_Member_Llc_Tax_Problem&diff=3298564&oldid=3295310"/> <updated>2025-06-03T10:22:44Z</updated> <summary type="html"><p></p><table class="diff diff-contentalign-left" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr style="vertical-align: top;" lang="en"> <td colspan="2" style="background-color: white; color:black; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: white; color:black; text-align: center;">Revision as of 10:22, 3 June 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1" >Line 1:</td><td colspan="2" class="diff-lineno">Line 1:</td></tr><tr><td class='diff-marker'>−</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del class="diffchange diffchange-inline">[https://www</del>.<del class="diffchange diffchange-inline">instapaper</del>.<del class="diffchange diffchange-inline">com</del>/<del class="diffchange diffchange-inline">p</del>/<del class="diffchange diffchange-inline">16409201 Registered </del>agent <del class="diffchange diffchange-inline">service provider] limited liability company, better named the LLC, is often a unique business choice</del>. [https://<del class="diffchange diffchange-inline">atavi</del>.<del class="diffchange diffchange-inline">com</del>/<del class="diffchange diffchange-inline">share/xag67lznbk9t Compliance reminders</del>] is <del class="diffchange diffchange-inline">actually very brand new </del>to the <del class="diffchange diffchange-inline">Improve. Wyoming &quot;imported&quot; it from Europe in 4 decades ago. It didn</del>'t <del class="diffchange diffchange-inline">catch on in one other states until an IRS ruling from </del>the <del class="diffchange diffchange-inline">late 1980s determined perchance taxed as a partnership in some ways</del>. <del class="diffchange diffchange-inline">This appeared </del>to <del class="diffchange diffchange-inline">turn it into </del>a <del class="diffchange diffchange-inline">good choice for small business ventures. Over </del>the <del class="diffchange diffchange-inline">next 20 years, the LLC has slowly become an accepted business entity choice and law already been developed around it</del>.&lt;br /&gt;&lt;br /&gt;<del class="diffchange diffchange-inline">First</del>, <del class="diffchange diffchange-inline">find out that forming an LLC </del>is <del class="diffchange diffchange-inline">not rocket does not work</del>. <del class="diffchange diffchange-inline">Any halfway decent attorney or online incorporation company will Incorporate LLC </del>be <del class="diffchange diffchange-inline">able to handle </del>the <del class="diffchange diffchange-inline">paperwork</del>.<del class="diffchange diffchange-inline">&lt;br /&gt;&lt;br /&gt;While there must be some order to this, usually affiliate marketers </del>are <del class="diffchange diffchange-inline">around the map lawn to the deeper layers of the well</del>. [https://<del class="diffchange diffchange-inline">urlscan</del>.<del class="diffchange diffchange-inline">io</del>/<del class="diffchange diffchange-inline">result/scan/ Registered agent fees</del>] . <del class="diffchange diffchange-inline">get lost in notion or they spend the vast majority of time chasing after something they </del>are <del class="diffchange diffchange-inline">ill</del>-<del class="diffchange diffchange-inline">prepared to suit</del>.&lt;br /&gt;&lt;br /&gt;<del class="diffchange diffchange-inline">Now it's time to obtain business organization formed prior to applying for SBA 8a status. You do not need to will need to go back and re</del>-<del class="diffchange diffchange-inline">do paperwork later. Take it from me</del>, <del class="diffchange diffchange-inline">group of big hassle </del>you in order to be <del class="diffchange diffchange-inline">avoid</del>. <del class="diffchange diffchange-inline">Don't procrastinate, make changes now!</del>&lt;br /&gt;&lt;br /&gt;<del class="diffchange diffchange-inline">Take a glance at </del>your <del class="diffchange diffchange-inline">photography and decide what associated with talent you </del>have <del class="diffchange diffchange-inline">and what potential you possess. Be critical of your work</del>, <del class="diffchange diffchange-inline">likewise have others critique your work for individuals</del>. <del class="diffchange diffchange-inline">Learn how make use of of constructive criticism to transform your photography. If a identity isn't where weight are not healthy it</del>, <del class="diffchange diffchange-inline">ask yourself</del>, <del class="diffchange diffchange-inline">what needs end up being improved? A person know your equipment (camera, lighting, etc) well a lot of? Do you just how </del>to <del class="diffchange diffchange-inline">read and meter your exposures? Do to be able to the right equipment, me.e.: hi resolution computer </del>and LLC incorporation <del class="diffchange diffchange-inline">Photo shop? You need an electric camera </del>to <del class="diffchange diffchange-inline">stay up with your competition</del>. <del class="diffchange diffchange-inline">In order to also important to be proficient in Photoshop and Lightroom and your digital work</del>-<del class="diffchange diffchange-inline">flows. It is considerably as you to beat any weakness with proper education </del>and <del class="diffchange diffchange-inline">practice before you take on photographing a wedding</del>.&lt;br /&gt;&lt;br /&gt;<del class="diffchange diffchange-inline">The approach </del>to <del class="diffchange diffchange-inline">realize your dreams is getting them </del>on to <del class="diffchange diffchange-inline">parts that you will understand. For example, suppose you need it </del>a <del class="diffchange diffchange-inline">furry friend</del>. <del class="diffchange diffchange-inline">Although the &quot;doggy </del>in <del class="diffchange diffchange-inline">the window&quot; become considered an impulse buy, it's not really simple as that anymore. There are other factors to contemplate such since its record of medical injections, breeding, health </del>and <del class="diffchange diffchange-inline">well being challenges and, in some cases, a dog passport</del>.&lt;br /&gt;&lt;br /&gt;<del class="diffchange diffchange-inline">This essay was originally written </del>for <del class="diffchange diffchange-inline">art businesses, as artists seldom come with business experiences</del>. <del class="diffchange diffchange-inline">However, it </del>can <del class="diffchange diffchange-inline">be adapted with other small business structures simply registered agent services </del>.&lt;br /&gt;&lt;br /&gt;<del class="diffchange diffchange-inline">Any business </del>can <del class="diffchange diffchange-inline">build effective systems</del>. <del class="diffchange diffchange-inline">Michael Gerber could be the established guru in search engine optimization</del>. <del class="diffchange diffchange-inline">His groundbreaking &quot;E</del>-<del class="diffchange diffchange-inline">Myth&quot; books </del>and <del class="diffchange diffchange-inline">philosophy have helped thousands of companies </del>to <del class="diffchange diffchange-inline">discover </del>the <del class="diffchange diffchange-inline">light and flourish. The thing is, we can build systems </del>for <del class="diffchange diffchange-inline">every possible routine situation faced by our carriers. But when we run into uncharted waters we often face concerns that can seem unmanageable at the time</del>.</div></td><td class='diff-marker'>+</td><td style="color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins class="diffchange diffchange-inline">Tax revenues would increase faster. Accelerated business growth would trigger higher corporate taxes. Personal income and payroll taxes would escalate as millions go for you to work</ins>. <ins class="diffchange diffchange-inline">The Yacht Buyers would pay more, combined with the rich Business Builders who choose to take their profits quarters</ins>.<ins class="diffchange diffchange-inline">&lt;br </ins>/<ins class="diffchange diffchange-inline">&gt;&lt;br </ins>/<ins class="diffchange diffchange-inline">&gt;(6) More record keeping than anyone have held stocks at an </ins>agent. <ins class="diffchange diffchange-inline">This one bothers some people. But </ins>[https://<ins class="diffchange diffchange-inline">samuelsen-vasquez-2</ins>.<ins class="diffchange diffchange-inline">blogbright.net</ins>/<ins class="diffchange diffchange-inline">how-start-off-a-home-based-business-create-money-addressing-envelopes Online registered agent</ins>] <ins class="diffchange diffchange-inline">'s not that bad. That means anyone might have to stick to top with the letters and news announcements that they send you (eg., say your company </ins>is <ins class="diffchange diffchange-inline">bought out, and need </ins>to <ins class="diffchange diffchange-inline">mail your certificate </ins>the <ins class="diffchange diffchange-inline">government financial aid - you don</ins>'t <ins class="diffchange diffchange-inline">want to miss </ins>the <ins class="diffchange diffchange-inline">deadline)</ins>. <ins class="diffchange diffchange-inline">Most with the they provide you can ignore (I never vote by proxy, go </ins>to <ins class="diffchange diffchange-inline">shareholder meetings, or even read may differ reports </ins>a <ins class="diffchange diffchange-inline">lot of </ins>the <ins class="diffchange diffchange-inline">time - I'll manage this in registered agent services long term when I have more time)</ins>.&lt;br /&gt;&lt;br /&gt;<ins class="diffchange diffchange-inline">Terms and definitions. There are 5 quantities of qualified essential health benefit selections: Platinum, the most expensive in gross premiums, is expected to obtain about 90% of claims; Gold</ins>, <ins class="diffchange diffchange-inline">which </ins>is <ins class="diffchange diffchange-inline">expected purchase up 80%; then there exists Silver at 70%, and Bronze at 60%</ins>. <ins class="diffchange diffchange-inline">For people people 30 years and under, there could </ins>be the <ins class="diffchange diffchange-inline">catastrophic high deductible policy</ins>. <ins class="diffchange diffchange-inline">These </ins>are <ins class="diffchange diffchange-inline">complete and comprehensive major medical plans for those Incorporate LLC and familys</ins>. [https://<ins class="diffchange diffchange-inline">graph</ins>.<ins class="diffchange diffchange-inline">org</ins>/<ins class="diffchange diffchange-inline">Selling-Your-House-In-21-Days-Or-Less-Course-Review-06-03 see details</ins>] <ins class="diffchange diffchange-inline">are guaranteed scenario</ins>. <ins class="diffchange diffchange-inline">There </ins>are <ins class="diffchange diffchange-inline">no pre</ins>-<ins class="diffchange diffchange-inline">existing situations</ins>.&lt;br /&gt;&lt;br /&gt;<ins class="diffchange diffchange-inline">Develop brand</ins>-<ins class="diffchange diffchange-inline">new Product, Program</ins>, <ins class="diffchange diffchange-inline">or Service - If </ins>you <ins class="diffchange diffchange-inline">have been itching </ins>in order to <ins class="diffchange diffchange-inline">on another product, program, or service, develop and test it now. When business accumulates again, bigger in time . offering will </ins>be <ins class="diffchange diffchange-inline">in place capable to go</ins>.&lt;br /&gt;&lt;br /&gt; <ins class="diffchange diffchange-inline">[https://auburn-crab-pzwc1w.mystrikingly.com/blog/stop-dreaming-and-start-</ins>your<ins class="diffchange diffchange-inline">-own-family-based-business-8-ways-to-get-started Legal registered agent] </ins>have <ins class="diffchange diffchange-inline">their own own websites</ins>, <ins class="diffchange diffchange-inline">where bookings can be made directly</ins>. <ins class="diffchange diffchange-inline">They seldom offer really cheap fares</ins>, <ins class="diffchange diffchange-inline">however</ins>, <ins class="diffchange diffchange-inline">as they offer these tickets </ins>to <ins class="diffchange diffchange-inline">on-line vendors </ins>and <ins class="diffchange diffchange-inline">traditional travel agents </ins>LLC incorporation <ins class="diffchange diffchange-inline">at reduced prices.Travel agents provide convenience, but ever have </ins>to <ins class="diffchange diffchange-inline">make a profit when selling their services, which enhances the price</ins>. <ins class="diffchange diffchange-inline">Buying on</ins>-<ins class="diffchange diffchange-inline">line offers convenience </ins>and <ins class="diffchange diffchange-inline">also lowest possible fares</ins>.&lt;br /&gt;&lt;br /&gt;<ins class="diffchange diffchange-inline">Yacht Clients who use their big incomes </ins>to <ins class="diffchange diffchange-inline">buy expensive toys, multiple homes, foreign currencies and so </ins>on <ins class="diffchange diffchange-inline">would pay more. People that want </ins>to <ins class="diffchange diffchange-inline">get in on </ins>a <ins class="diffchange diffchange-inline">pro-business tax perks would certainly be motivated devote in Small C Corps</ins>. <ins class="diffchange diffchange-inline">All existing incentives make investments </ins>in <ins class="diffchange diffchange-inline">larger corporations (preferred capital gain </ins>and <ins class="diffchange diffchange-inline">qualified dividend rates) would be</ins>.&lt;br /&gt;&lt;br /&gt;<ins class="diffchange diffchange-inline">20. Also start a marketing-branding study which will include marketing channels </ins>for <ins class="diffchange diffchange-inline">positioning and accounts. Then go back and reserve web domain names that fit the designer brand</ins>. <ins class="diffchange diffchange-inline">Now you </ins>can <ins class="diffchange diffchange-inline">start designing internet site</ins>.&lt;br /&gt;&lt;br /&gt;<ins class="diffchange diffchange-inline">It's critical that </ins>can <ins class="diffchange diffchange-inline">easily time obtaining good forex investments broker</ins>. <ins class="diffchange diffchange-inline">Following are [https://postheaven</ins>.<ins class="diffchange diffchange-inline">net/metercarp2/6</ins>-<ins class="diffchange diffchange-inline">a-person-need-to-know-before-starting-a-courier-business registered agent appointment] understand what to review </ins>and <ins class="diffchange diffchange-inline">should help help </ins>to <ins class="diffchange diffchange-inline">make an informed decision and select </ins>the <ins class="diffchange diffchange-inline">right forex trading broker </ins>for <ins class="diffchange diffchange-inline">your needs</ins>.</div></td></tr></table></summary> <author><name>Cheeksave3</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Intergenerational_academic_freedom_within_the_last_hundred_years_in_Europe&diff=3298563&oldid=0</id> <title>Intergenerational academic freedom within the last hundred years in Europe</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Intergenerational_academic_freedom_within_the_last_hundred_years_in_Europe&diff=3298563&oldid=0"/> <updated>2025-06-03T10:22:42Z</updated> <summary type="html"><p>Created page with &quot;Poor aqueous solubility is one of the key reasons for slow dissolution rate and poor intestinal absorption and finally that causes low therapeutic efficacy of many existing dr...&quot;</p><p><b>New page</b></p><div>Poor aqueous solubility is one of the key reasons for slow dissolution rate and poor intestinal absorption and finally that causes low therapeutic efficacy of many existing drugs. Tamoxifen citrate (TMX) (BCS Class II drug) with low water solubility has poor oral bioavailability in the range of 20%-30%, therefore, high doses are required for treatment with TMX. Self-assemblage of amphiphilic polymers leads to the formation of polymeric micelles which makes them unique nano-carriers with excellent biocompatibility, low toxicity, enhanced blood circulation time, and solubilization of poorly water-soluble drugs. In this study poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) triblock copolymer, which has been approved by FDA for oral application was used to benefit its micellar solubilization effect. Self-assembled micelles were prepared for the delivery of TMX and this way TMX solubility was increased approximately 60 times. TMX-treated cells showed 38.06 ± 1.5% viability at 50 µM concentration for 24 h; 66.71 ± 11.6% viability at 25 µM concentration for 48 h, at the same conditions TMX-loaded micelles exhibited 24.994 ± 0.25% and 43.36 ± 4.37% cell viability, respectively (p less then 0.05). These results showed that the encapsulation of TMX into PEG-PPG-PEG micelles facilitated the cellular uptake, which led to an increased cytotoxicity in MCF-7 cancer cells. Tablet formulation containing lyophilized TMX-loaded micelles was showed an improved dissolution than commercial TMX tablet (Tamoxifen® TEVA). It can be reasonably expected that the obtained drug dissolution rate and increased cytotoxicity to tumor cells will result in an increase of TMX bioavailability and tolerability associated with an important dose reduction and decreased side effects.Background The cognitive dysmetria theory of schizophrenia proposes that communication between the cerebellum and cerebral cortex is disrupted by structural and functional abnormalities, resulting in psychotic symptoms and cognitive deficits. Methods Using publicly available data, resting-state functional connectivity (rsFC) was calculated from 20 hemispheric cerebellar lobules as seed regions of interest to the rest of the brain. Group differences in rsFC between individuals with schizophrenia (SZ) and healthy controls (HCs) were computed, and relationships between rsFC and symptom severity and cognitive functioning were explored. Results HCs demonstrated stronger connectivity than SZ between several cerebellar lobules and cortical regions, most robustly between motor-related cerebellar lobules (V and VIIIa/b) and temporal and parietal cortices. In addition, seven of nine lobules in which reduced cerebellocortical connectivity was observed showed diagnosis × processing speed interactions; HC showed a positive implications for downstream effects on higher order cognitive functions, in line with the cognitive dysmetria theory.Lactate, a molecule originally considered metabolic waste, is now associated with a number of important physiological functions. Although the roles of lactate as a signaling molecule, fuel source, and gluconeogenic substrate have garnered significant attention in recent reviews, a relatively underexplored and emerging role of lactate is its control of energy intake (EI). [https://www.selleckchem.com/products/tak-901.html read more] To expand our understanding of the physiological roles of lactate, we present evidence from early infusion studies demonstrating the ability of lactate to suppress EI in both rodents and humans. We then discuss findings from recent human studies that have utilized exercise intensity and/or sodium bicarbonate supplementation to modulate endogenous lactate and examine its impact on appetite regulation. These studies consistently demonstrate that greater blood lactate accumulation is associated with greater suppression of the hunger hormone ghrelin and subjective appetite, thereby supporting a role of lactate in the control of EI. To stimulate future research investigating the role of lactate as an appetite-regulatory molecule, we also highlight potential underlying mechanisms explaining the appetite-suppressive effects of lactate using evidence from rodent and in vitro cellular models. Specifically, we discuss the ability of lactate to 1) inhibit the secretory function of ghrelin producing gastric cells, 2) modulate the signaling cascades that control hypothalamic neuropeptide expression/release, and 3) inhibit signaling through the ghrelin receptor in the hypothalamus. Unravelling the role of lactate as an appetite-regulatory molecule can shed important insight into the regulation of EI, thereby contributing to the development of interventions aimed at combatting overweight and obesity.Free fatty acid (FFA) receptors FFA1 and FFA4 are omega-3 molecular targets in metabolic diseases; however, their function in cancer cachexia remains unraveled. We assessed the role of FFA1 and FFA4 receptors in the mouse model of cachexia induced by Lewis lung carcinoma (LLC) cell implantation. Naturally occurring ligands such as α-linolenic acid (ALA) and docosahexaenoic acid (DHA), the synthetic FFA1/FFA4 agonists GW9508 and TUG891, or the selective FFA1 GW1100 or FFA4 AH7614 antagonists were tested. FFA1 and FFA4 expression and other cachexia-related parameters were evaluated. GW9508 and TUG891 decreased tumor weight in LLC-bearing mice. Regarding cachexia-related end points, ALA, DHA, and the preferential FFA1 agonist GW9508 rescued body weight loss. Skeletal muscle mass was reestablished by ALA treatment, but this was not reflected in the fiber cross-sectional areas (CSA) measurement. Otherwise, TUG891, GW1100, or AH7614 reduced the muscle fiber CSA. Treatments with ALA, GW9508, GW1100, or AH7614 restored white adipose tissue (WAT) depletion. As for inflammatory outcomes, ALA improved anemia, whereas GW9508 reduced splenomegaly. Concerning behavioral impairments, ALA and GW9508 rescued locomotor activity, whereas ALA improved motor coordination. Additionally, DHA improved grip strength. Notably, GW9508 restored abnormal brain glucose metabolism in different brain regions. The GW9508 treatment increased leptin levels, without altering uncoupling protein-1 downregulation in visceral fat. LLC-cachectic mice displayed FFA1 upregulation in subcutaneous fat, but not in visceral fat or gastrocnemius muscle, whereas FFA4 was unaltered. Overall, the present study shed new light on FFA1 and FFA4 receptors' role in metabolic disorders, indicating FFA1 receptor agonism as a promising strategy in mitigating cancer cachexia.</div></summary> <author><name>Periodrabbi49</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Moderate_Organizations_to_produce_a_new_Portable_Request_about_Wholesome_Practices&diff=3298562&oldid=0</id> <title>Moderate Organizations to produce a new Portable Request about Wholesome Practices</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Moderate_Organizations_to_produce_a_new_Portable_Request_about_Wholesome_Practices&diff=3298562&oldid=0"/> <updated>2025-06-03T10:22:35Z</updated> <summary type="html"><p>Created page with &quot;We also indicated that hippocampal dependent memory and learning task were improved by FICZ treatment and impaired by the AHR and Wnt/ß-catenin inhibition. In this study for...&quot;</p><p><b>New page</b></p><div>We also indicated that hippocampal dependent memory and learning task were improved by FICZ treatment and impaired by the AHR and Wnt/ß-catenin inhibition. In this study for the first time, we demonstrated that the endogenous ligand of AHR, FICZ, has a positive effect on short- and long-term memory as well as learning skills. This ability is possibly mediated by the AHR-Wnt/ß-catenin cross-talk.Glucagon-like peptide-1 (GLP-1) is a gut-derived peptide that has various physiological actions. One of its main actions is the regulation of blood glucose level when it is elevated as it potentiates insulin release. It is also known that GLP-1 protects neurons from damage caused by neurodegenerative diseases. [https://www.selleckchem.com/products/2-bromohexadecanoic-acid.html selleckchem] Lixisenatide is one of the GLP-1 analogues that has a strong affinity to the GLP-1 receptor. Experimental animal studies have shown that it holds a neuroprotective effect in Parkinson, myocardial, and cerebral ischemic disease animal models. The beneficial effect of lixisenatide on the brain after cerebral ischemia-reperfusion (I/R) is not clarified yet; thus, it needs further explanatory studies. Our research is the first to study the effect of lixisenatide on myeloperoxidase (MPO) and toll-like receptors (TLRs)/mitogen-activated protein kinase (MAPK) pathway in a rat model of cerebral I/R. Lixisenatide with 2 doses 0.7 and 7&amp;nbsp;nmol/kg was given intraperitoneal in 2 different groups for 14&amp;nbsp;days; then, the bilateral common carotid artery was occluded for 1&amp;nbsp;h followed by reperfusion for 1&amp;nbsp;h. Examination of hippocampus CA1 neurons by Nissl stain showed that the number of intact neurons was elevated in the lixisenatide-treated group related to the control group (I/R group). Lixisenatide exhibited neuroprotection action possibly via downregulation of MPO, TLR2/4, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), and pP38 and upregulation of phosphorylated extracellular signal-regulated kinase (pERK1/2); thus, this study gives possible link between lixisenatide and TLR/MAPK pathway following cerebral I/R and supports the use of lixisenatide for neuroprotection against stroke.Hereditary spastic paraplegia (HSP) includes a number of inherited disorders which are characterized by stiffness in the lower extremities and progressive gait disturbance. Mutations in terms of spastic gait genes (SPGs) are responsible for occurrence of different types of HPS with autosomal recessive, X-linked recessive, and autosomal dominant modes of inheritance. In the current case report, we identified a mutation in SPG11 gene in a female patient with progressive stiffness of lower extremities and atrophy of corpus callosum and the &quot;lynx ear&quot; sign in brain MRI. Whole exome sequencing (WES) revealed a homozygote frameshift deletion variant in SPG11 gene (NM001160227 exon 28 c.4746delT, p.N1583Tfs*23). This variant is a null variant classified as a pathogenic variant (PVS1) according to ACMG standards and guidelines. The frequency of this variant in 1000G, ExAC, and Iranome databases was 0. This study shows the role of WES in the identification of disease-causing mutations in a disease such as HSP which can be caused by diverse mutations in several genes.Here, we monitored the expression of three genes (hsp70, hsp22, and hsf1) involved in heat shock response in Drosophila melanogaster in males and females of different age. Also, we investigated age- and sex-dependent expression of three major genes participating in the production of hydrogen sulfide (H2S) (cse, cbs, and mst), implicated in stress resistance and aging. In addition to the control strain, we monitored the expression of all of these genes in a cbs knockout strain (cbs-/-) generated using the CRISPR technique. The tested strains differ in the induction capacities of the studied genes. Relative to the control strain, under normal conditions, the cbs-/- strain expresses all of the studied genes more abundantly, especially hsp22. In the control strain, aging leads to a dramatic increase in hsp22 synthesis, whereas in the cbs-/- strain, hsp22 induction is not pronounced. Furthermore, in 30-day-old cbs-/- flies, the constitutive expression of hsp70 and mst is decreased. Surprisingly, in the cbs-/- strain, we detected an upregulation of hsf1 transcription in the 30-day-old females. After heat shock in the control strain, hsp70 and hsp22 induction decreased with age in males and hsp22 decreased in females, while in the cbs-/- strain, a pronounced drop in the induction capacity of both hsp genes was seen in 30-day-old males and females. However, in most cases, the expression levels of hsf1 and H2S-producing genes do not exhibit pronounced changes depending on sex, age, or heat shock. Flies of control and cbs-/- strain exhibited strong reduction in basal thermotolerance with age. Our data suggest a cross-talk between the two studied ancient and universal adaptive systems.PURPOSE Thyroid dysfunction may affect the risk of cardiovascular disease and mortality through effects on myocardial and vascular tissue and metabolism. Levels of thyroid stimulating hormone (TSH) indicates thyroid function. We aimed to assess the association between TSH-levels and incident ischemic heart disease (IHD), incident stroke, and all-cause mortality. METHODS We included 13,865 participants (18-71 years, 51.6% women) from five cohort studies conducted during 1974-2008 were included. TSH was measured at the baseline examination and classified as 10 mU/l. Incident IHD, incident stroke, and all-cause mortality were identified in registries until ultimo 2013. Data were analysed by multivariate Cox regression with age as underlying time axis. Results from the individual cohorts were pooled by random-effects meta-analysis. RESULTS The crude incidence rate was for IHD 7.8 cases/1000 person years (PY); stroke 5.4 cases/1000 PY; and all-cause mortality 11.3 deaths/1000 PY (mean follow-up 14 years). Analyses showed no statistically significant associations between TSH-levels and incident IHD or incident stroke in the partly or fully adjusted models. There was a statistically significant association between TSH of 2.5-5 mU/l and all-cause mortality (hazard ratio 1.145 (95% CI 1.004-1.306) compared with TSH of 0.4-2.5 mU/l in the fully adjusted model. CONCLUSION The results do not provide evidence of a harmful effect of decreased or increased TSH on IHD or stroke in the general population. However, there is some indication of an elevated risk for all-cause mortality with TSH 2.5-5 mU/l compared with 0.4-2.5 mU/l.</div></summary> <author><name>Tempocicada2</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Middletonhelms9463</id> <title>User:Middletonhelms9463</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Middletonhelms9463"/> <updated>2025-06-03T10:22:30Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Middletonhelms9463&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Middletonhelms9463 (page does not exist)"><bdi>Middletonhelms9463</bdi></a> was created</p></summary> <author><name>Middletonhelms9463</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Kjertrevino9817</id> <title>User:Kjertrevino9817</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Kjertrevino9817"/> <updated>2025-06-03T10:22:29Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Kjertrevino9817&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Kjertrevino9817 (page does not exist)"><bdi>Kjertrevino9817</bdi></a> was created</p></summary> <author><name>Kjertrevino9817</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Effect_associated_with_essential_oil_droplet_habits_throughout_electrochemical_micromembrane_tissues_in_dealing_with_oilwater_emulsions_using_lowsalt_concentrations&diff=3298561&oldid=0</id> <title>Effect associated with essential oil droplet habits throughout electrochemical micromembrane tissues in dealing with oilwater emulsions using lowsalt concentrations</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Effect_associated_with_essential_oil_droplet_habits_throughout_electrochemical_micromembrane_tissues_in_dealing_with_oilwater_emulsions_using_lowsalt_concentrations&diff=3298561&oldid=0"/> <updated>2025-06-03T10:22:18Z</updated> <summary type="html"><p>Created page with &quot;Of note is that new constituents, including alkaloids, dietary fiber, and other bioactive substances, as well as the antiviral, hypoglycemic, lipid-lowering, and neuroprotecti...&quot;</p><p><b>New page</b></p><div>Of note is that new constituents, including alkaloids, dietary fiber, and other bioactive substances, as well as the antiviral, hypoglycemic, lipid-lowering, and neuroprotective effects of jujube fruit, are systematically reviewed here for the first time. Meanwhile, problems affecting the exploitation of jujube fruit resources are discussed and further research directions proposed. Therefore, this review provides a useful bibliography for the future development of jujube-based products and the utilization of jujube nutritional components in functional foods.&lt;br /&gt;&lt;br /&gt; The programmed death ligand 1 (PD-L1) SP142 assay with a 1% immune cell (IC) cutoff is approved for the selection of advanced triple-negative breast cancer (TNBC) patients for atezolizumab treatment. We aimed to evaluate the interobserver concordance of PD-L1 scoring and inter-assay variability of various PD-L1 assays in TNBC.&lt;br /&gt;&lt;br /&gt; Thirty patients with primary TNBC were selected, and SP142, SP263, 22C3, and E1L3N assays were performed. PD-L1 staining in ICs and tumor cells (TCs) was scored by 10 pathologists who were blinded to the assay. The interobserver concordance among pathologists and the inter-assay variability of the four PD-L1 assays were analyzed. For SP142, the intraobserver concordance among the six pathologists was analyzed after training.&lt;br /&gt;&lt;br /&gt; The adjusted means of PD-L1 IC scoring ranged from 6.2% to 12.9% for the four assays; the intraclass correlations showed moderate (0.584-0.649) reader concordance. The PD-L1 IC scoring with a 1% cutoff resulted in identical scoring in 40.0%-66.7% of cases and a poor to moderate agreement (Fleiss κ statistic [FKS] = 0.345-0.534) for the four assays. The SP142 assay had the widest range of positive rate (56.5%-100.0%), lowest number of cases with identical scoring, and lowest FKS at 1% cutoff. [https://www.selleckchem.com/products/gsk650394.html GSK650394 cell line] Pairwise comparison of adjusted means showed significantly decreased PD-L1 staining in SP142 compared with the other assays in both ICs and TCs. As for the intraobserver concordance in the SP142 assay, the overall percent agreement was 87.8% with a 1% IC cutoff. After training, the proportion of cases with identical scoring at a 1% IC cutoff increased to 70.0%; the FKS also increased to 0.610.&lt;br /&gt;&lt;br /&gt; The concordance of PD-L1 IC scoring among pathologists was low, at the 1% cutoff for the SP142 assay without training. SP142 showed the lowest PD-L1 expression in both IC and TC.&lt;br /&gt;&lt;br /&gt;The concordance of PD-L1 IC scoring among pathologists was low, at the 1% cutoff for the SP142 assay without training. SP142 showed the lowest PD-L1 expression in both IC and TC.&lt;br /&gt;&lt;br /&gt; Raloxifene is a selective estrogen receptor modulator (SERM), and raloxifene treatment for osteoporosis is reimbursable under the Korean National Health Insurance. Evidence suggests that SERMs use reduces the risk of breast cancer in Asian population. Herein, we retrospectively investigated the protective effect of raloxifene on breast cancer rates in Korean population.&lt;br /&gt;&lt;br /&gt; Using the Health Insurance Review and Assessment Service database, we selected women with osteoporosis aged 50 years and above. Patients treated for at least 2 years with raloxifene were assigned to the user group, whereas the remaining patients were assigned to the non-user group. The effect on breast cancer risk was assessed using the Cox proportional-hazards model with a time-dependent covariate to adjust for immortal time bias.&lt;br /&gt;&lt;br /&gt; A total of 322,870 women who were registered between 2010 and 2011 were included. The user group comprised 0.7% (n = 2,307) of the total population. The mean age was 65.7 ± 8.0 years and 67.2 ± 8.6 years in the user and non-user groups, respectively (&lt;br /&gt;&lt;br /&gt; &amp;lt; 0.001). There was no difference in the previous use of estrogen replacement between the 2 groups (&lt;br /&gt;&lt;br /&gt; = 0.087). The incidence of breast cancer per 1,000 person-years was 0.49 (n = 8) and 0.68 (n = 1,714) in the user and non-user groups, respectively (hazard ratio [HR], 0.63, 95% confidence interval [CI], 0.32-1.27). HR decreased with increase in the treatment duration, but this change was not statistically significant (HR, 1.00, 95% CI, 0.32-3.11 in 2-3 years; HR, 0.63, 95% CI, 0.20-1.94 in 3-4 years; and HR, 0.41, 95% CI, 0.10-1.65 in 4-5 years).&lt;br /&gt;&lt;br /&gt; Long-term treatment with raloxifene in women with osteoporosis was not significantly associated with a reduction in breast cancer rates. However, further investigation is required for a conclusive proof.&lt;br /&gt;&lt;br /&gt;Long-term treatment with raloxifene in women with osteoporosis was not significantly associated with a reduction in breast cancer rates. However, further investigation is required for a conclusive proof.Salvage mastectomy is currently considered the standard of care for ipsilateral breast tumor recurrence (IBTR) after breast-conserving surgery (BCS) and postoperative radiotherapy (RT). Alternative treatment options for these patients, such as a second BCS followed by repeated RT, have been suggested. The panel of the Italian Association of Radiotherapy and Clinical Oncology developed clinical recommendations for second BCS followed by re-irradiation over mastectomy alone for women with IBTR using the Grades of Recommendation, Assessment, Development, and Evaluation methodology and the evidence to decision framework. The following outcomes were identified by the panel locoregional control, metastasis-free survival, overall survival, and cancer-specific survival; acute and late toxicity, specific late toxicity, second locoregional tumor, and death related to treatment. An Embase and PubMed literature search was performed by two independent authors. Five retrospective observational studies were eligible for inclusion in the present analysis. According to the reports in the literature and our analysis, the advantages of second quadrantectomy and re-irradiation (re-QUART) outweigh its side effects, with overall good rates of survival and adequate toxicity without increasing costs. Given the very low level of evidence, the panel stated that a second BCS plus re-irradiation can be considered as an alternative to salvage mastectomy for selected patients with IBTR.&lt;br /&gt;&lt;br /&gt; Women with large and/or ptotic breasts are generally not considered candidates for nipple-sparing mastectomy because of concerns regarding the high incidence of postoperative complications including ischemic complications. Therefore, we adopted a vertical skin resection technique for nipple-sparing mastectomy, and obtained satisfactory results following immediate autologous breast reconstruction. In this study, we aimed to describe our operative technique and review its outcomes.&lt;br /&gt;&lt;br /&gt; Between January 2010 and March 2017, immediate autologous breast reconstructions were performed in 28 patients with moderate or large ptotic breasts after nipple-sparing mastectomy using the vertical reduction pattern. Grade II ptosis was observed in 12 patients, and 16 patients were classified as having grade III ptosis.&lt;br /&gt;&lt;br /&gt; Of the 28 patients, 21 received abdominal free flap reconstruction. In the remaining 7 patients, extended latissimus dorsi flaps were used in conjunction with anatomic implants. The mean weight of the excised breast tissue in the 2 groups was 575 g and 482 g, respectively.</div></summary> <author><name>Sarahrotate0</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Multidimensional_Child_Low_income_through_the_Little_one_RightsBased_Tactic_Any_Hidden_School_Analysis_to_be_able_to_Pricing_Little_one_Low_income_Organizations_inside_Mexico&diff=3298560&oldid=0</id> <title>Multidimensional Child Low income through the Little one RightsBased Tactic Any Hidden School Analysis to be able to Pricing Little one Low income Organizations inside Mexico</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Multidimensional_Child_Low_income_through_the_Little_one_RightsBased_Tactic_Any_Hidden_School_Analysis_to_be_able_to_Pricing_Little_one_Low_income_Organizations_inside_Mexico&diff=3298560&oldid=0"/> <updated>2025-06-03T10:22:17Z</updated> <summary type="html"><p>Created page with &quot;A 35-year-old man was diagnosed with psoriatic arthritis treated with methotrexate and cyclosporine, the latter was then interrupted. Subsequently, etanercept was introduced,...&quot;</p><p><b>New page</b></p><div>A 35-year-old man was diagnosed with psoriatic arthritis treated with methotrexate and cyclosporine, the latter was then interrupted. Subsequently, etanercept was introduced, administered for 10 years and then replaced with ustekinumab. Six months after treatment with ustekinumab, patient underwent a chest CT scan for pneumonia, showing an anterior mediastinal mass which turned out to be a thymoma. He was referred to our department with fatigue, difficulty in raising arms and transient episodes of diplopia after exertion. Clinical history revealed that these symptoms had begun about 7 years previously but were ascribed to psoriatic arthritis. A diagnosis of anti-acetylcholine receptor antibodies positive myasthenia gravis was made; a higher dosage of methotrexate and prednisone were started with regression of symptoms. Our case increases the number of clinical reports of myasthenia gravis onset in patients with a history of rheumatic disease treated with anti-TNFα drugs. We speculate that ustekinumab could contribute to clinical worsening. OBJECTIVE To determine the level of knowledge and current management of starting insulin treatment by Primary Care physicians, and its impact on metabolic control. MATERIALS AND METHODS A mainly qualitative exploratory sequential study, with a phenomenological approach, followed by a quantitative phase. The study included 37 primary care physicians from the Andalusian Health Service. Socio-demographic and clinical care variables were analysed. Univariate and bivariate analyses were performed. RESULTS There was a wide variability between Primary Care physicians in the level of knowledge of treatment with insulins (low knowledge 13.5%; medium knowledge 59.5%; high knowledge 27.0%). There was a direct relationship between the level of knowledge and the attainment of HbA1c goals (as the level of knowledge increased, the metabolic control improved). The most common basal insulins prescribed were insulin glargine U-100 (56.8%), followed by insulin glargine U-300 (29.7%), and neutral protamine hagedorn (NPH) insulin (8.1%). There was a trend to show a different prescription pattern with basal insulins (as the level of knowledge decreased, the prescription of mixed and NPH insulins increased). More than one-third (35.1%) of primary care physicians did not know more complex patterns of treatment with insulins. CONCLUSIONS Only 27% of Primary Care physicians had a high knowledge about treatment with insulins. There was a direct relationship between the level of knowledge about insulins and glycaemic control. It is necessary to improve the knowledge about insulin therapy in order to optimise metabolic control and reduce the risk of complications. INTRODUCTION High altitude headache (HAH) and acute mountain sickness (AMS) are common pathologies at high altitudes. There are similarities between AMS and migraine headaches, with nausea being a common symptom. Several studies have shown ibuprofen can be effective for AMS prophylaxis, but few have addressed treatment. Metoclopramide is commonly administered for migraine headaches but has not been evaluated for HAH or AMS. We aimed to evaluate metoclopramide and ibuprofen for treatment of HAH and AMS. METHODS We performed a prospective, double-blinded, randomized, field-based clinical trial of metoclopramide and ibuprofen for the treatment of HAH and AMS in 47 adult subjects in the Mount Everest region of Nepal. [https://www.selleckchem.com/products/estradiol-benzoate.html click here] Subjects received either 400 mg ibuprofen or 10 mg metoclopramide in a 1-time dose. Lake Louise Score (LLS) and visual analog scale of symptoms were measured before and at 30, 60, and 120 min after treatment. RESULTS Subjects in both the metoclopramide and ibuprofen arms reported reduced headache severity and nausea compared to pretreatment values at 120 min. The ibuprofen group reported 22 mm reduction in headache and 6 mm reduction in nausea on a 100 mm visual analog scale at 120 min. The metoclopramide group reported 23 mm reduction in headache and 14 mm reduction in nausea. The ibuprofen group reported an average 3.5-point decrease on LLS, whereas the metoclopramide group reported an average 2.0-point decrease on LLS at 120 min. CONCLUSIONS Metoclopramide and ibuprofen may be effective alternative treatment options in HAH and AMS, especially for those patients who additionally report nausea. INTRODUCTION Most recreational whitewater fatalities are caused by fixed underwater entrapment or by &quot;flush drowning,&quot; an obscure term frequently associated with high-volume rivers, continuous rapids, cold water, and a lack of prolonged underwater entrapment. Although entrapment drowning is typically associated with submersion hypoxia, flush drownings likely involve diverse mechanisms of death; as such, a concise definition is elusive. This said, certain risk factors may be predictively associated with flush drownings. We attempt to further characterize causes of fatal river accidents and possible effects of water temperature on injury pattern. METHODS We reviewed river mortality data collected from the American Whitewater Association accident database comparing fatal whitewater accident trends in the Rocky Mountain region versus the Southeastern United States. We limited data from the Southeast to the months of June through August to create a warm water cohort. We then divided lethal accidents into flush drowning, entrapment submersion, or miscellaneous events, defining each category in specific terms. RESULTS Flush drownings were more common in the Rocky Mountains than in the Southeast subgroup and involved older victims on average than entrapment drowning or miscellaneous events. Entrapment drownings were common in both regions, primarily occurring at fallen trees or rock formations. CONCLUSIONS Flush drownings appear to occur more frequently in older persons. Although hypothetical, the relative increase in flush drowning in the Rocky Mountains might partly be the result of colder water temperatures. If the cause of flush drowning is better understood, safety in whitewater recreation may be improved. INTRODUCTION Triathlon is one of the fastest growing sports in the United Kingdom. However, in recent years several deaths have occurred. The intention of this study is to identify these cases and examine the role cardiovascular disease played in these deaths. METHODS An extensive online search was performed to identify triathlon-related deaths (TRDs) in the United Kingdom and UK citizens who died during or as a result of competing in triathlons abroad. British Triathlon provided the number of participants who took part in UK-based events. Coroners provided information on all those who died. RESULTS Between 2009 and 2015, 991,186 participants took part in British Triathlon-sanctioned events. Five TRDs in the United Kingdom were identified. The mortality rate was 0.5 per 100,000 participants. Deaths occurred during or after the swim (3), cycle (1), and run (1) events. During the same period, 5 TRDs were identified among UK citizens competing abroad. These deaths occurred during or after the swim (2), cycle (1), and run (2) events.</div></summary> <author><name>Tripnight71</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Mccartymagnussen3305</id> <title>User:Mccartymagnussen3305</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Mccartymagnussen3305"/> <updated>2025-06-03T10:22:16Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Mccartymagnussen3305&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Mccartymagnussen3305 (page does not exist)"><bdi>Mccartymagnussen3305</bdi></a> was created</p></summary> <author><name>Mccartymagnussen3305</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=The_sunday_paper_construction_including_AI_design_along_with_enzymological_tests_stimulates_recognition_involving_SARSCoV2_3CL_protease_inhibitors_along_with_activitybased_probe&diff=3298559&oldid=0</id> <title>The sunday paper construction including AI design along with enzymological tests stimulates recognition involving SARSCoV2 3CL protease inhibitors along with activitybased probe</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=The_sunday_paper_construction_including_AI_design_along_with_enzymological_tests_stimulates_recognition_involving_SARSCoV2_3CL_protease_inhibitors_along_with_activitybased_probe&diff=3298559&oldid=0"/> <updated>2025-06-03T10:22:12Z</updated> <summary type="html"><p>Created page with &quot;25 [2.63-4.02]) in both MI and heart failure cohorts. Hemodynamic data was available in 1116 (79%) patients. Elevated biventricular filling pressures were common among patient...&quot;</p><p><b>New page</b></p><div>25 [2.63-4.02]) in both MI and heart failure cohorts. Hemodynamic data was available in 1116 (79%) patients. Elevated biventricular filling pressures were common among patients with CS, and right atrial pressure was associated with increased mortality and higher SCAI Stage.&lt;br /&gt;&lt;br /&gt; Our findings support an association between the proposed SCAI staging system and in-hospital mortality among patient with heart failure and MI. We further identify that venous congestion is common and identifies patients with CS at high risk for in-hospital mortality. These findings provide may inform future management protocols and clinical studies.&lt;br /&gt;&lt;br /&gt;Our findings support an association between the proposed SCAI staging system and in-hospital mortality among patient with heart failure and MI. We further identify that venous congestion is common and identifies patients with CS at high risk for in-hospital mortality. These findings provide may inform future management protocols and clinical studies.&lt;br /&gt;&lt;br /&gt; Patients with heart failure have significant symptom burden, care needs, and often a progressive course to end-stage disease. Palliative care referrals may be helpful but it is currently unclear when patients should be referred and by whom. We conducted a systematic review of the literature to examine referral criteria for palliative care among patients with heart failure.&lt;br /&gt;&lt;br /&gt; We searched Ovid, MEDLINE, Ovid Embase, and PubMed databases for articles in the English language from the inception of databases to January 17, 2019 related to palliative care referral in patients with heart failure. Two investigators independently reviewed each citation for inclusion and then extracted the referral criteria. Referral criteria were then categorized thematically.&lt;br /&gt;&lt;br /&gt; Of the 1199 citations in our initial search, 102 articles were included in the final sample. We identified 18 categories of referral criteria, including 7 needs-based criteria and 10 disease-based criteria. The most commonly discussed criterion was physical or emotional symptoms (n=51 [50%]), followed by cardiac stage (n=46 [45%]), hospital utilization (n=38 [37%]), prognosis (n=37 [36%]), and advanced cardiac therapies (n=36 [35%]). Under cardiac stage, 31 (30%) articles suggested New York Heart Association functional class ≥III and 12 (12%) recommended New York Heart Association class ≥IV as cutoffs for referral. Prognosis of ≤1 year was mentioned in 21 (21%) articles as a potential trigger; few other criteria had specific cutoffs.&lt;br /&gt;&lt;br /&gt; This systematic review highlighted the lack of consensus regarding referral criteria for the involvement of palliative care in patients with heart failure. Further research is needed to identify appropriate and timely triggers for palliative care referral.&lt;br /&gt;&lt;br /&gt;This systematic review highlighted the lack of consensus regarding referral criteria for the involvement of palliative care in patients with heart failure. Further research is needed to identify appropriate and timely triggers for palliative care referral.Media coverage can impact support for health policies and, ultimately, compliance with those policies. Prior research found consistent, high support for Tobacco 21 policies, which raise the minimum legal age of tobacco purchase to 21, among adults and nonsmoking youth. However, a recent study found support (i.e., agreement with the statement &quot;The legal age to buy tobacco cigarettes should be increased from 18 to 21&quot;) among 13-20-year-old smokers increased from 2014 until mid-2016 and then declined steadily through mid-2017. To assess whether media coverage could be related to young smokers' changing support, we conducted an exploratory content analysis to identify texts about Tobacco 21 in a large corpus of tobacco texts (N = 135,691) published in four popular media sources from 2014 to 2017. For this content analysis, we developed a novel methodological approach that combined supervised and unsupervised machine learning methods and could be useful in other areas of communication research. We found that the prevalence of Tobacco 21 media coverage and Tobacco 21 support among young smokers exhibited similar temporal patterns for much of the study period. These findings highlight the need for continued research into the effects of media coverage on Tobacco 21 support among young smokers, a group that must comply with Tobacco 21 policies in order to ensure maximum effectiveness. This research is of particular utility following the 2019 passage of a federal Tobacco 21 regulation, as the public health impact of this regulation could be limited by low public support, and thus low rates of policy compliance.Due to their health-promoting effects green tea catechins have gained a keen interest in recent years in the context of bodyweight reduction treatments and alleviation of inflammatory diseases. This study was designed to evaluate the impact of native and thermally modified catechins (TMC) on the body weight gain, fatty acid profile in subcutaneous adipose tissue and the activity of the enzymes involved in lipid metabolism regulation AMP-dependent protein kinase (AMPK) and acetyl-CoA carboxylase (ACC) in apoE-deficient mice maintained on a high-fat diet. We observed that TMC decreased bodyweight gain as compared to the control group. Furthermore, TMC increased AMPK activity and reduced ACC activity in the metabolically important tissues intestine, liver and subcutaneous adipose tissue and affected adipose tissue fatty acid composition. Native catechins produced less pronounced effects. These results suggest that TMC down-regulate endogenous fatty acid synthesis, which should be taken into account in dietary applications of catechins.&lt;br /&gt;&lt;br /&gt; Atrial fibrillation is a complex condition associated with a broad spectrum of symptoms, coupled with variability in the frequency, duration and severity of symptoms. [https://www.selleckchem.com/products/bay-1816032.html Serine inhibitor] Early treatment seeking is important to reduce the risk of stroke, heart failure and dementia. Despite the increasing prevalence, there remains a limited understanding of the symptom experience prior to an atrial fibrillation diagnosis, and how these experiences influence treatment-related decisions and time frames.&lt;br /&gt;&lt;br /&gt; This qualitative study aimed to explore the symptom experiences of patients receiving an early diagnosis of less than 48 hours and a late diagnosis of 48 hours or more after symptom awareness.&lt;br /&gt;&lt;br /&gt; Twenty-six adults were interviewed guided by the symptom experience model. The symptom checklist was used to probe patient's symptoms further. Data were analysed using a two-step approach to thematic analysis utilising concepts from the symptom experience model.&lt;br /&gt;&lt;br /&gt; The two groups differed in their perception, evaluation and response to symptoms.</div></summary> <author><name>Hotcry1</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Thorough_substance_and_metabolism_profiling_of_antihyperglycemic_productive_small_percentage_through_Clerodendranthi_Spicati_Herba&diff=3298558&oldid=0</id> <title>Thorough substance and metabolism profiling of antihyperglycemic productive small percentage through Clerodendranthi Spicati Herba</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Thorough_substance_and_metabolism_profiling_of_antihyperglycemic_productive_small_percentage_through_Clerodendranthi_Spicati_Herba&diff=3298558&oldid=0"/> <updated>2025-06-03T10:22:07Z</updated> <summary type="html"><p>Created page with &quot;Myositis ossificans (MO) is a benign non-neoplastic condition in which heterotopic bone formation occurs in soft tissues. Neurogenic MO is one variant of MO where the lesion i...&quot;</p><p><b>New page</b></p><div>Myositis ossificans (MO) is a benign non-neoplastic condition in which heterotopic bone formation occurs in soft tissues. Neurogenic MO is one variant of MO where the lesion is a result of neurological disorders, including brain and spinal cord injuries, especially when followed by immobility and spasticity. MO can also be a result of direct trauma or even genetic mutations.&lt;br /&gt;&lt;br /&gt; We present three cases of young men (16, 37, and 22-year-old) who developed MO of the hip joint following brain or spinal cord injuries. One of them had also sustained a direct trauma to the affected hip joint at the time of the accident. All three patients presented with inability to walk independently due to diminished range of motion at the affected joint. X-rays and computerized tomography (CT) scans with 3-dimentional (3D) reconstruction suggested the diagnosis of MO, but the serum alkaline phosphatase was within normal limits at the time of presentation. [https://www.selleckchem.com/products/dir-cy7-dic18.html DiR chemical molecular weight] The first case had bilateral involvement with unmistakable separation betwe non-operative methods fail to provide an adequate range of motion around the hip joint. Pre-operative assessment utilizing 3D-CT scans proved to be essential in dictating the appropriate surgical approach. During post-operative follow-ups, the physiotherapy and oral indomethacin provided additional improvement in outcome and patients' satisfaction.&lt;br /&gt;&lt;br /&gt;The surgical management of MO is indicated when non-operative methods fail to provide an adequate range of motion around the hip joint. Pre-operative assessment utilizing 3D-CT scans proved to be essential in dictating the appropriate surgical approach. During post-operative follow-ups, the physiotherapy and oral indomethacin provided additional improvement in outcome and patients' satisfaction.&lt;br /&gt;&lt;br /&gt; Volar locking plate fixation of distal radius fractures is commonly performed because of its good clinical outcomes. The flexor carpi radialis (FCR) approach is one of the most popular approaches to dissecting the volar side of the distal radius because of its simplicity and safety. We describe an extremely rare case of an absent FCR identified during a volar approach for fixation of a distal radius fracture.&lt;br /&gt;&lt;br /&gt; A 40-year-old male with comminuted distal radius fracture underwent surgery using the usual FCR approach and volar locking plate. We could not identify the absence of the FCR tendon preoperatively because of severe swelling of the distal forearm. At first, we wrongly identified the palmaris longus (PL) tendon as the FCR because it was the tendinous structure at the most radial location of the volar distal forearm. When we found the median nerve just radial to the PL tendon, we were then able to identify the anatomical abnormality in this case. To avoid iatrogenic neurovascular injuries, we changed thhe FCR is designated as a favorable landmark because of its superficially palpable location, strong and thick structure, and rare anatomical variations, there is the possibility of iatrogenic complications in cases of the absence of the FCR. We suggest that surgeons should have a detailed knowledge of the range of possible anomalies to complete the fixation of a distal radius fracture safely.&lt;br /&gt;&lt;br /&gt; Tumor-induced osteomalacia (TIO) is a rare paraneoplastic disorder caused by tumors that produce fibroblast growth factor 23 (FGF23) resulting in phosphate wasting and inadequate bone mineralization. Complete resection of the tumor can be curative. However, these tumors are typically difficult to find anatomically due to small size and location.&lt;br /&gt;&lt;br /&gt; We present the case of a patient who presented for evaluation of recurrent fractures and hypophosphatemia in the setting of elevated FGF23 suggestive of TIO. 68Gallium-DOTATATE revealed multiple somatostatin avid lesions in several ribs, left acetabulum, sacrum, right tibia, and feet, some of which appeared with fracture on computed tomography scan, initially concerning for metastatic disease. However, the lesion in acetabulum was considered the culprit tumor given its remarkably higher maximum standard uptake values. Complete surgical removal of the FGF23-secreting tumor led to cure of this disease.&lt;br /&gt;&lt;br /&gt; This case report highlights the challenges with functional imaging differentiating fractures from the culprit lesion and reports on a novel surgical technique that allowed for surgical cure while preserving the hip joint.&lt;br /&gt;&lt;br /&gt;This case report highlights the challenges with functional imaging differentiating fractures from the culprit lesion and reports on a novel surgical technique that allowed for surgical cure while preserving the hip joint.&lt;br /&gt;&lt;br /&gt; Calcaneus fractures are rare in the pediatric population, and avulsion fracture of the calcaneal tuberosity is even less common. In adults, those fractures are usually associated with poor bone quality, however, this is not the case in children. It is a fracture that requires emergent intervention to prevent devastating skin and soft-tissue-related complications.&lt;br /&gt;&lt;br /&gt; We report a case of a 9-year-old female who had a displaced calcaneal tuberosity fracture with heel skin impending compromise, after a fall at an indoor gymnastic facility. The child had a history of acute lymphoblastic leukemia, diagnosed at age 4, she was in remission at the time of injury. In the present report, besides reporting a rare injury among the pediatric population, we also describe the operative management, the post-operative course, and we review the literature.&lt;br /&gt;&lt;br /&gt; Pediatric calcaneal tuberosity fractures, although rare, can lead to devastating complications if not addressed promptly, and should be treated in an expedited fashion.&lt;br /&gt;&lt;br /&gt;Pediatric calcaneal tuberosity fractures, although rare, can lead to devastating complications if not addressed promptly, and should be treated in an expedited fashion.&lt;br /&gt;&lt;br /&gt; Anterior cord syndrome (ACS) is a type of incomplete spinal cord injury caused by either direct compression of the anterior spinal cord, or by ischemia of the anterior spinal artery. This phenomenon has neither been described transiently nor intraoperatively.&lt;br /&gt;&lt;br /&gt; We describe the case of a 61-year-old male who developed intermittent and transient anterior spinal cord syndrome secondary to hypotension related hypoperfusion of the anterior spinal artery after elective cervical spine surgery. Through close blood pressure monitoring and intensive care unit support, the patient regained full neurological recovery.&lt;br /&gt;&lt;br /&gt; Anterior spinal cord syndrome is a rare condition affecting the anterior 2/3 of the spinal cord, resulting in incomplete paralysis. Blood flow can be disrupted through the anterior spinal artery, either through thrombosis or hypotension. We describe our rare case so that surgeons may recognize this potentially devastating condition.&lt;br /&gt;&lt;br /&gt;Anterior spinal cord syndrome is a rare condition affecting the anterior 2/3 of the spinal cord, resulting in incomplete paralysis.</div></summary> <author><name>Rabbitcod6</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Dualfunctional_permeable_MOFs_using_ordered_guests_encapsulation_with_regard_to_roomtemperature_phosphorescence_along_with_whitelightemission&diff=3298557&oldid=0</id> <title>Dualfunctional permeable MOFs using ordered guests encapsulation with regard to roomtemperature phosphorescence along with whitelightemission</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Dualfunctional_permeable_MOFs_using_ordered_guests_encapsulation_with_regard_to_roomtemperature_phosphorescence_along_with_whitelightemission&diff=3298557&oldid=0"/> <updated>2025-06-03T10:22:07Z</updated> <summary type="html"><p>Created page with &quot;BACKGROUND Rapid and accurate diagnosis of mucopolysaccharidoses (MPS) is still a challenge due to poor access to screening and diagnostic methods and to their extensive clini...&quot;</p><p><b>New page</b></p><div>BACKGROUND Rapid and accurate diagnosis of mucopolysaccharidoses (MPS) is still a challenge due to poor access to screening and diagnostic methods and to their extensive clinical heterogeneity. The aim of this work is to perform laboratory biochemical testing for confirming the diagnosis of mucopolysaccharidosis (MPS) for the first time in Morocco. METHODS Over a period of twelve months, 88 patients suspected of having Mucopolysaccharidosis (MPS) were referred to our laboratory. Quantitative and qualitative urine glycosaminoglycan (GAG) analyses were performed, and enzyme activity was assayed on dried blood spots (DBS) using fluorogenic substrates. Enzyme activity was measured as normal, low, or undetectable. RESULTS Of the 88 patients studied, 26 were confirmed to have MPS; 19 MPS I (Hurler syndrome; OMIM #607014/Hurler-Scheie syndrome; OMIM #607015), 2 MPS II (Hunter syndrome; OMIM #309900), 2 MPS IIIA (Sanfilippo syndrome; OMIM #252900), 1 MPS IIIB (Sanfilippo syndrome; OMIM #252920) and 2 MPS VI (Maroteaux-Lamy syndrome; OMIM #253200). Parental consanguinity was present in 80.76% of cases. Qualitative urinary glycosaminoglycan (uGAGs) assays showed abnormal profiles in 31 cases, and further quantitative urinary GAG evaluation and Thin Layer Chromatography (TLC) provided important additional information about the likely MPS diagnosis. [https://www.selleckchem.com/products/wnt-c59-c59.html selleck compound] The final diagnosis was confirmed by specific enzyme activity analysis in the DBS samples. CONCLUSIONS The present study shows that the adoption of combined urinary substrate analysis and enzyme assays using dried blood spots can facilitate such diagnosis, offer an important tool for an appropriate supporting care, and a specific therapy, when available.BACKGROUND The current study aims to investigate the expression of miR-587 in platelets of patients with acute coronary syndrome (ACS) and its correlation with the severity of coronary artery disease. METHODS One hundred thirty-nine patients with ACS who underwent coronary angiography (CAG) and hospitalized in the Department of Cardiology of Affiliated Tengzhou Central People's Hospital of Jining Medical University were selected. In addition, 42 subjects with normal CAG results were selected as the control group. The relative expression of platelet miR-587 was analyzed between ACS patients and control subjects. RESULTS The relative expression of platelet miR-587 and Gensini score in acute myocardial infarction (AMI) patients were significantly higher than those in the unstable angina pectoris (UA) and control groups (median (IQR) 1.97 (0.47) vs. 1.49 (0.43) vs. 1.04 (0.35); 65.07 (21.6) vs. 44.58 (28.56) vs. 13.67 (11.8)). Furthermore, the relative level of miR-587 in ACS patients with three vessel lesions was significantly higher than those with double vessel le-sion and single vessel lesion (2.68 (0.64) vs. 1.85 (0.53) vs. 1.22 (0.40)). Additionally, the relative expression of platelet miR-587 in patients with severe coronary artery disease was significantly higher than in those with moderate or mild coronary artery disease (2.44 (0.59) vs. 1.70 (0.49) vs. 0.96 (0.32)). Pearson's correlation analysis showed that the Gensini score and creatine kinase isoenzyme (CK-MB) of ACS patients were positively correlated with the expression of platelet miR-587 (r = 0.785, p = 0.000; r = 0.806, p = 0.000). CONCLUSIONS The expression of platelet miR-587 was closely related to the severity of coronary artery stenosis and could be used as a potential target for diagnosis or prognosis.BACKGROUND Invasive Gram-positive bacilli infections are commonly encountered in immunocompromised patients. In this paper, we report a bacteremia caused by Turicella otitidis in a patient with diffuse large B-cell lymphoma. METHODS Bacteria was identified by VITEK MALDI-TOF MS. Drug sensitivity was analyzed by disk diffusion method. RESULTS MALDI-TOF MS data demonstrated that the infection bacteria was Turicella otitidis. Drug susceptibility data showed that Turicella otitidis was possibly sensitive to vancomycin, polymyxin B, and chloramphenicol. Body temperature of the patient dropped after administration of vancomycin. The data indicated that vancomycin could be used to treat the infections caused by Turicella otitidis. CONCLUSIONS MALDI-TOF MS can be used for the rapid and accurate identification of Turicella otitidis. Vancomycin can be used to treat the infection caused by Turicella otitidis. This study may provide a reference for the diagnosis and treatment of Turicella otitidis.BACKGROUND Do D-dimer levels influence the pregnancy outcomes after treatment with low molecular weight heparin (LMWH) in women of recurrent miscarriage (RM), repeated biochemical pregnancy losses (BPL), and a positive test for antiphospholipid antibodies (aPLs)? METHODS This study was a retrospective chart review of 569 RM patients who were identified as having a history of BPL and a positive aPL. These patients were grouped into three groups according to their treatment plan including those who received low dose aspirin (LDA) alone (group A), LDA plus LMWH after ovulation therapy (group B), and LDA plus LMWH after pregnancy confirmation (group C). We hypothesized that the administration of LMWH after ovulation increased the rates of live birth. D-dimer may predict the pregnancy outcome after treatment. RESULTS The live birth rate of group B and group C is significantly higher than group A (86.96% and 66.80% vs. 52.89%, p less then 0.0001, respectively). The live birth rate in group A, B, and C with elevated D-dimer is 36.92%, 90.52%, and 61.60% respectively. However, there is no significant difference in live birth rate among those who had normal baseline D-dimer. CONCLUSIONS These results suggest that LMWH therapy is more effective in improving the live birth rate when given after ovulation than after pregnancy confirmation. The plasma D-dimer assay can possibly guide LMWH treatment appropriately.BACKGROUND To analyze the difference of the antibiotic resistance of Acinetobacter baumannii (A. baumannii) isolated from our hospital between 2014 and 2017. METHODS We retrospectively evaluated the patients with a confirmed diagnosis of A. baumannii infection at a tertiary general hospital in Guilin during the period between January 2014 and December 2017. The following clinical and demographic data were collected age, gender, specimens, microbiology results, and antibiotic resistance patterns of isolates. Bacterial identification and susceptibility testing were performed using MALDI-TOF MS and VITEK 2 COMPACT systems. The results were analyzed according to the Clinical and Laboratory Standards Institute (CLSI) 2018 definitions. RESULTS From 2014 to 2017, 1,294 strains of A. baumannii were detected, 41.5% of which came from ICU. The sputum separation rate from ICU was significantly higher than those from non-ICU (p less then 0.05). Except for amikacin, levofloxacin, and compound sulfamethoxazole, the resistant rates of the others increased year by year.</div></summary> <author><name>Kayakswim27</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Epidemic_associated_with_BTK_variations_within_men_Algerian_habits_along_with_agammaglobulinemia_as_well_as_severe_W_cellular_lymphopenia&diff=3298556&oldid=0</id> <title>Epidemic associated with BTK variations within men Algerian habits along with agammaglobulinemia as well as severe W cellular lymphopenia</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Epidemic_associated_with_BTK_variations_within_men_Algerian_habits_along_with_agammaglobulinemia_as_well_as_severe_W_cellular_lymphopenia&diff=3298556&oldid=0"/> <updated>2025-06-03T10:22:06Z</updated> <summary type="html"><p>Created page with &quot;Such prevalence not only require support from health and social care services, at times it require an emergency response from front line services. The police are increasingly...&quot;</p><p><b>New page</b></p><div>Such prevalence not only require support from health and social care services, at times it require an emergency response from front line services. The police are increasingly involved in responding to crisis and transporting people to emergency departments rather than paramedics. Such police intervention can escalate situations and intensify levels of distress resulting in unintended consequences including increasing public stigma and the criminalization of mental illness. My experience suggests that often the response to psychiatric pain is different to when we are experiencing physical pain. In this narrative I explore the various emergency pathways I experienced when in psychiatric distress including experiences with law enforcement services, emergency departments and psychiatric services. The potential impact of the responses and whether there are opportunities to develop better, more compassionate response. © 2020 John Wiley &amp;amp; Sons Ltd.BACKGROUND AND AIMS When measuring inequalities in health, public health and addiction research has tended to focus on differences in average life-span between socio-economic groups. This does not account for the extent to which age of death varies between individuals within socio-economic groups or whether this variation differs between groups. This study assesses (1) socio-economic inequalities in both average life-span and variation in age at death, (2) the extent to which these inequalities can be attributed to alcohol-specific causes (i.e. those attributable only to alcohol) and (3) how this contribution has changed over time. DESIGN Cause-deleted life table analysis of national mortality records. SETTING England and Wales, 2001-16. CASES All-cause and alcohol-specific deaths for all adults aged 18+, stratified by sex, age and quintiles of the index of multiple deprivation (IMD). MEASUREMENTS Life expectancy at age 18&amp;nbsp;yearss and standard deviation in age at death within IMD quintiles and the contribution Using both measures can provide a fuller picture of overall inequalities in health. © 2020 The Authors. Addiction published by John Wiley &amp;amp; Sons Ltd on behalf of Society for the Study of Addiction.BACKGROUND Hyponatremia is common in patients with acute heart failure (HF). Our aim was to determine the impact of sodium disturbances on mortality and readmissions in HF with reduced left ventricular ejection fraction (HFrEF), preserved ejection fraction (HFpEF), and mid-range ejection fraction (HFmrEF). METHODS Prospective multicentre consecutive registry in 20 hospitals including patients admitted due to acute HF in cardiology departments. Sodium 145 mmol/L hypernatremia, and 135-145 mmol/L normal. RESULTS A total of 1309 patients were included. Mean age was 72.0 ± 11.9 years, 810 (61.9%) were male. Mean serum sodium level was 138.6 ± 4.7 mmol/L at hospital admission, and 138.1 ± 4.1 mmol/L at discharge. The evolution of sodium levels was normal-at-admission/normal-at-discharge 941 (71.9%), abnormal-at-admission/normal-at-discharge 127 (9.7%), normal-at-admission/abnormal-at-discharge 155 (11.8%), and abnormal-at-admission/abnormal-at-discharge 86 (6.6%). Hyponatremia at discharge was more common in HFrEF (109 (20.7%)) than in HFpEF (79 (13.9%)) and HFmrEF (27 (12%)), P&amp;nbsp;=&amp;nbsp;0.003. The prevalence of hypernatremia at discharge was similar in the three groups HFrEF (10 (1.9%)), HFpEF (12 (2.1%)), and HFmrEF (4 (1.9%)), P&amp;nbsp;=&amp;nbsp;0.96. In multivariate analysis, abnormal sodium concentrations at hospital admission (Hazard Ratio (HR) 1.42, 95% confidence interval (CI) 1.15-1.76, P&amp;nbsp;=&amp;nbsp;0.001), and discharge (HR 1.33, 95% CI 1.08-1.64, P&amp;nbsp;=&amp;nbsp;0.007) were both independently associated with increased mortality and readmissions at 12 months. [https://www.selleckchem.com/products/d-ap5.html D-AP5 cost] CONCLUSIONS Hyponatremia and hypernatremia at admission and discharge predict a poor outcome in patients with acute HF, regardless of LVEF. Hyponatremia at discharge is more frequent in HFrEF than in the other LVEF groups. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.PURPOSE A significant number of patients with acute coronary syndrome (ACS) are nonadherent to aspirin after hospital discharge, with an associated increased risk of subsequent cardiovascular events. The purpose of this pilot study was to test the efficacy of a telehealth intervention based on behavioral economics to improve aspirin adherence following hospitalization for ACS. METHODS We enrolled 130 participants (c¯X = 58 ± 10.7 years of age, 38% female, 45% black) from two hospitals. Patients were eligible if they owned a smartphone and were admitted to the hospital for ACS, prescribed aspirin at discharge, and responsible for administering their own medications. Consenting participants were randomized to the intervention or usual care group. The intervention group was eligible to receive up to $50 per month if they took their medicine daily, with $2 per day deducted if a dose was missed. All participants received an electronic monitoring (EM) pill bottle containing a 90-day supply of aspirin, which was used to measure adherence calculated as the proportion of prescribed drug taken using the EM device. Based on the skewness in the adherence distribution, quantile regression was used to evaluate the effect of the intervention on median adherence over time. RESULTS After 90 days, adherence fell in the control group but remained high in the intervention group (median adherence 81% vs 90%, P = .18). Rehospitalization was higher in the control group (24% vs 13%, P = .17). CONCLUSION A loss aversion behavioral economics-based telehealth intervention is a promising approach to improving aspirin adherence following hospitalization for ACS. © 2020 John Wiley &amp;amp; Sons Ltd.Despite improvements in medications, devices and understanding of the disease, about half of all asthma patients worldwide remain inadequately controlled, suggesting the need for a new approach to asthma management. Poor adherence to prescribed maintenance therapy and over-reliance on SABA reliever medication is a common cause of inadequate control. This article reviews published data from 6- to 12-month, double-blind, RCT and open-label real-world studies involving budesonide/formoterol maintenance and reliever therapy (MART) and relevant comparator approaches to asthma management, and considers how these compare in achieving the treatment goals described in guidelines. The data confirm that patients with asthma treated with budesonide/formoterol MART achieved the same or better asthma symptom control compared with ICS/LABA plus SABA regimens at similar or higher ICS doses, with consistently lower rates of exacerbations and considerably lower annual requirement for oral corticosteroids. These findings have been confirmed across a range of severities of persistent asthma.</div></summary> <author><name>Combbean2</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=CalpainMediated_Mitochondrial_Destruction_An_Emerging_Procedure_Leading_to_Heart_failure_Disease&diff=3298555&oldid=0</id> <title>CalpainMediated Mitochondrial Destruction An Emerging Procedure Leading to Heart failure Disease</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=CalpainMediated_Mitochondrial_Destruction_An_Emerging_Procedure_Leading_to_Heart_failure_Disease&diff=3298555&oldid=0"/> <updated>2025-06-03T10:21:57Z</updated> <summary type="html"><p>Created page with &quot;005).&lt;br /&gt;&lt;br /&gt; The Perme Score has an MDC of 1.36 points and shows evidence of being sensitive to change. Therefore, the findings validate the responsiveness of the instrum...&quot;</p><p><b>New page</b></p><div>005).&lt;br /&gt;&lt;br /&gt; The Perme Score has an MDC of 1.36 points and shows evidence of being sensitive to change. Therefore, the findings validate the responsiveness of the instrument.&lt;br /&gt;&lt;br /&gt;The Perme Score has an MDC of 1.36 points and shows evidence of being sensitive to change. Therefore, the findings validate the responsiveness of the instrument.&lt;br /&gt;&lt;br /&gt; To compare a Mediterranean diet (MED) with a high-fibre vegetarian diet (HFV) in terms of hunger-satiety perception through post-prandial assessment of appetite-related hormones glucagon-like peptide 1 (GLP-1) and oxyntomodulin, as well as self-rated visual analogue scale (VAS) quantification, in overweight/obese subjects with type 2 diabetes (T2D).&lt;br /&gt;&lt;br /&gt; Twelve T2D subjects (Male to female ratio = 75), mean age 63 ± 8.5 years, were enrolled in a randomized, controlled, crossover study. Participants consumed an MED meal as well as an isocaloric meal rich in complex carbohydrate as well as an isocaloric MED meal in two different visits with a 1-week washout period between the two visits. Appetite ratings, glucose/insulin, and gastrointestinal hormone concentrations were measured at fasting and every 30' until 210' following meal consumption.&lt;br /&gt;&lt;br /&gt; GLP-1 and oxyntomodulin levels were significantly higher following MED meal compared with HFV meals (210' area under the curve, p &amp;lt; 0.022 and p &amp;lt; 0.023, respectively). Both MED and HFV meal resulted in a biphasic pattern of GLP-1 and oxyntomodulin, although MED meal was related to a delayed, significantly higher second GLP-1 peak at 150' compared with that of HFV meal (p &amp;lt; 0.05). MED meal was related to lower glucose profile compared with HFV meal (p &amp;lt; 0.039), whereas we did not observe significant changes in terms of self-reported VAS scores and insulin trend.&lt;br /&gt;&lt;br /&gt; In T2D overweight/obese subjects, an MED meal is more effective than a HFV meal in terms of post-prandial plasma glucose homoeostasis and GLP-1 and oxyntomodulin release. These changes were not confirmed by VAS appetite self-assessment over a 210' period.&lt;br /&gt;&lt;br /&gt;In T2D overweight/obese subjects, an MED meal is more effective than a HFV meal in terms of post-prandial plasma glucose homoeostasis and GLP-1 and oxyntomodulin release. These changes were not confirmed by VAS appetite self-assessment over a 210' period.This paper explores the potential contribution of timebanking, an innovative volunteering scheme, to the co-production of preventive social care with adults in England. Interest in volunteering in social care has increased as one proposed solution to the international crisis of a rising demand for services in juxtaposition with decreased resources. Volunteering has been particularly promoted in preventive services that prevent or delay care needs arising. Despite sustained interest in volunteering and co-production in social care, little is known about how theory translates into practice. Reporting implementation data from a Realistic Evaluation of six case studies in England, this paper explores one volunteering scheme, timebanking. The research explores how timebanks were working, what contribution they can make to adult social care, and whether they are an example of co-production. Data collected included interviews, focus groups or open question responses on surveys from 84 timebank members, and semi-structured interviews with 13 timebank staff. Each timebank was visited at least twice, and all timebank activity was analysed for a period of 12 months. Data were triangulated to improve reliability. The research found that in practice, timebanks were not working as described in theory, there were small numbers of person-to-person exchanges and some timebanks had abandoned this exchange model. Timebanks faced significant implementation challenges including managing risk and safeguarding and the associated bureaucracy, a paternalistic professional culture and the complexity of the timebank mechanism which required adequate resources. Lessons for timebanks are identified, as well as transferable lessons about co-production and volunteering in social care if such schemes are to be successful in the future.An intermediate phenotype of a disease is a trait in the path of pathogenesis from genetic predisposition to disease manifestation. Identifying intermediate phenotypes with high heritability is helpful in delineating the genetics of a disorder. [https://www.selleckchem.com/products/bay-2666605.html BAY 2666605 in vitro] In this study, we aimed to examine various traits with regards to obesity, cardiovascular risk and upper airway structure to identify potential intermediate phenotypes of childhood obstructive sleep apnea (OSA). Children aged between 6 and 18 years and their parents and siblings were recruited. All subjects underwent anthropometric measurements, cardiovascular risk assessment, sonographic measurement of lateral parapharyngeal wall (LPW) thickness, X-ray cephalometry and overnight polysomnography. A total of 34 phenotypes were examined. One hundred and one families consisting of 127 children (46 overweight) and 198 adults (84 overweight) were recruited. Heritability of obstructive apnea-hypopnea index (OAHI) was significant in overweight (h2 = 0.54) but not normal-weight individuals (h2 = 0.12). LPW thickness (h2 = 0.68) and resting blood pressure (h2 = 0.36 and 0.43 for systolic blood pressure [SBP] and diastolic blood pressure [DBP], respectively) were significantly heritable and associated with OAHI. Moreover, these traits were found to have shared genetic variance with OAHI in the overweight subgroup. Hyoid bone position also had significant heritability (h2 = 0.55) and association with OAHI but genetic correlation with OSA severity was not demonstrated. These findings suggest that LPW thickness and resting blood pressure are possible intermediate phenotypes of OSA independent of body mass index, especially in overweight patients. Identifying genes relevant to these phenotypes may help to elucidate the genetic susceptibility of OSA.Alzheimer's disease (AD) accounts for an estimated 60% to 80% of all dementia cases. The present study is aimed at evaluating the neuroprotective efficacy of vitexin, an apigenin flavone glycoside using transgenic Caenorhabditis elegans strain (CL2006) of AD. The neuroprotective effect of vitexin was determined using physiological assays, quantitative polymerase chain reaction, and Western blotting. The results of survival and paralysis assay indicate that vitexin (200 μM) significantly extended the lifespan of the nematodes. Vitexin-treated nematodes showed a significant reduction in the expression of Aβ, ace-1, and ace-2 genes when compared to control. Further, vitexin significantly upregulated the expression of acr-8 and dnj-14, and increased the lifespan of the nematodes. Vitexin was also found to modulate the unfolded protein response genes (hsp-4, pek-1, ire-1, and xbp-1) and suppress the expression of Aβ. Overall, the results show that vitexin acts as a neuroprotective agent and protects transgenic C. elegans strains from Aβ proteotoxicity.</div></summary> <author><name>Woodlift49</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=10_Apps_That_Can_Help_You_Manage_Your_Electric_Fireplace_Wall&diff=3298554&oldid=0</id> <title>10 Apps That Can Help You Manage Your Electric Fireplace Wall</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=10_Apps_That_Can_Help_You_Manage_Your_Electric_Fireplace_Wall&diff=3298554&oldid=0"/> <updated>2025-06-03T10:21:56Z</updated> <summary type="html"><p>Created page with &quot;&lt;h2&gt;Electric Fireplace Wall Mounted: The Ultimate Guide&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Electric fireplaces have actually surged in popularity for many years, mainly due to their aesthetic...&quot;</p><p><b>New page</b></p><div>&lt;h2&gt;Electric Fireplace Wall Mounted: The Ultimate Guide&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Electric fireplaces have actually surged in popularity for many years, mainly due to their aesthetic appeal, energy performance, and convenience. Among the myriad of choices offered, wall-mounted electric fireplaces have actually become a top choice for house owners and tenants alike. This short article checks out the essential benefits of electric wall-mounted fireplaces, their installation, maintenance, and answers to regularly asked concerns.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h2&gt;What is a Wall Mounted Electric Fireplace?&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;A wall-mounted electric fireplace is a kind of heating unit that is installed on a wall, getting rid of the need for standard venting or chimney systems. They utilize electric heat elements and LED lighting to simulate the appearance of flickering flames, offering a relaxing ambiance and warmth without the intricacies of wood-burning or gas fireplaces.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;Benefits of Wall Mounted Electric Fireplaces&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;ol&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Space Saving&lt;/strong&gt;: Ideal for small living spaces, wall-mounted electric fireplaces take up minimal floor area while adding a touch of beauty to the space.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Easy Installation&lt;/strong&gt;: Most designs can be mounted on any wall with a power outlet, making them simpler to install than standard fireplaces.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Energy Efficiency&lt;/strong&gt;: Electric fireplaces typically need less energy to run, making them more affordable in terms of heating.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Varied Styles&lt;/strong&gt;: Ranging from contemporary minimalist designs to more standard models, the world of electric fireplaces offers many styles to fit any design.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Environmentally Friendly&lt;/strong&gt;: These fireplaces do not produce smoke or emissions, making them a safer alternative for indoor use.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt;&lt;/ol&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;Key Features to Consider&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;When selecting a wall-mounted electric fireplace, there are a variety of features that ought to be taken into consideration:&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;ul&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Heat Output&lt;/strong&gt;: Measured in BTUs (British Thermal Units), sufficient heat output is important for warming the desired area successfully.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Design and Aesthetic&lt;/strong&gt;: The style needs to match the home's design. Choices vary from smooth glass fronts to classic mantel styles.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Control Options&lt;/strong&gt;: Look for models with push-button controls, app integration, or wise home compatibility.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Safety Features&lt;/strong&gt;: Auto shut-off alternatives and cool-touch glass can improve security, particularly in homes with kids or pets.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Installation Type&lt;/strong&gt;: Decide between flush-mount (recessed) and surface-mount designs based on personal choice and room design.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt;&lt;/ul&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;Setup Process&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Installing a wall-mounted electric fireplace can frequently be an uncomplicated procedure, however it is essential to follow the maker's instructions:&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;ol&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Select Location&lt;/strong&gt;: Choose an area that is near an electrical outlet with adequate wall clearance and visibility.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Gather Tools&lt;/strong&gt;: Tools required might include a drill, screwdriver, level, and stud finder.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Mount the Bracket&lt;/strong&gt;: Most fireplaces include brackets for mounting. Utilize a level to ensure it is straight.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Hang the Fireplace&lt;/strong&gt;: Attach the fireplace to the mounted bracket firmly.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Connect Power&lt;/strong&gt;: Plug in the fireplace to the outlet and protect any cables to guarantee they are not a tripping threat.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Test Functionality&lt;/strong&gt;: Before finishing, guarantee the fireplace lights and heat features work properly.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt;&lt;/ol&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;Upkeep Tips&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;To keep wall-mounted electric fireplaces in great working order, think about the following upkeep practices:&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;ol&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Regular Cleaning&lt;/strong&gt;: Dust the glass and surrounding locations to preserve appearance. Tidy with a soft fabric and non-abrasive cleaner.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Look for Obstructions&lt;/strong&gt;: Ensure vents or air inlets are clear of dust and debris.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Yearly Check-up&lt;/strong&gt;: Consider having actually the system inspected by an expert for wear and tear if it is utilized thoroughly.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;p&gt;&lt;strong&gt;Replace Bulbs as Needed&lt;/strong&gt;: LED lights have a long life, but it's a good idea to change burnt-out bulbs without delay.&lt;/p&gt;&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt;&lt;/ol&gt;&lt;br /&gt;&lt;br /&gt;&lt;h2&gt;Comparison Table: Wall-Mounted Electric Fireplaces&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;table&gt; &lt;br /&gt;&lt;br /&gt; &lt;thead&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;th&gt;Function&lt;/th&gt; &lt;br /&gt;&lt;br /&gt; &lt;th&gt;Standard Fireplace&lt;/th&gt; &lt;br /&gt;&lt;br /&gt; &lt;th&gt;Wall Mounted Electric Fireplace&lt;/th&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;/thead&gt; &lt;br /&gt;&lt;br /&gt; &lt;tbody&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Area Requirement&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Needs substantial floor space&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Very little flooring space required&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Ventilation&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Requires a chimney/vent&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;No venting required&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Setup&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Complex and time-consuming&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Simple installation&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Energy Efficiency&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Less effective&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Extremely energy-efficient&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Security&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Hot surfaces and emissions&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Normally cool to touch&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Expense&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;High preliminary cost + setup&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Lower initial cost&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tbody&gt;&lt;br /&gt;&lt;br /&gt;&lt;/table&gt;&lt;br /&gt;&lt;br /&gt;&lt;h2&gt;Often Asked Questions (FAQs)&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;1. Just how much does a wall-mounted electric fireplace expense?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;The cost can vary substantially based upon style and features. Standard models might start around ₤ 150, while high-end versions can exceed ₤ 1,000.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;2. Can I mount an electric fireplace throughout my home?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Yes, as long as there is an electrical outlet neighboring and the wall can support the system's weight.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;3. Are wall-mounted electric fireplaces safe?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Yes, a lot of designs include built-in security features like thermal shut-off, making them safe for indoor usage.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;4. Do wall-mounted electric fireplaces need much upkeep?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;They need minimal upkeep, generally simply dusting and looking for any obstructions.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;5. Can I utilize a wall-mounted electric fireplace as the main heat source?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;While some designs provide considerable heat, they are mostly designed to supplement heating, making them perfect for little areas.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Wall-mounted electric fireplaces serve as an elegant, safe, and efficient heating option, specifically fit for modern-day lifestyles. They integrate the appeal of standard fireplaces with the convenience of electric heating, making them an attractive option for any home. Comprehending [https://canvas.instructure.com/eportfolios/3812303/entries/13766511 Electric Wall Fire Place] , installation, and upkeep can assist property owners and occupants enjoy the warmth and aesthetic appeal they offer years to come.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;</div></summary> <author><name>Josephtulip0</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Stomatologiya_evKt</id> <title>User:Stomatologiya evKt</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Stomatologiya_evKt"/> <updated>2025-06-03T10:21:53Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Stomatologiya_evKt&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Stomatologiya evKt (page does not exist)"><bdi>Stomatologiya evKt</bdi></a> was created</p></summary> <author><name>Stomatologiya evKt</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=HD_or_Nothing_How_to_Preserve_the_Top_Livestream_Highlights&diff=3298553&oldid=0</id> <title>HD or Nothing How to Preserve the Top Livestream Highlights</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=HD_or_Nothing_How_to_Preserve_the_Top_Livestream_Highlights&diff=3298553&oldid=0"/> <updated>2025-06-03T10:21:34Z</updated> <summary type="html"><p>Created page with &quot;&lt;p&gt;In the current digital age, live streaming has evolved into a huge part of our online experience. Services like YouTube have transformed the way we interact with content cr...&quot;</p><p><b>New page</b></p><div>&lt;p&gt;In the current digital age, live streaming has evolved into a huge part of our online experience. Services like YouTube have transformed the way we interact with content creators, allowing us to view live events, gaming sessions, and performances in real-time. Nonetheless, as exciting as it is to participate with live broadcasts, many of us wish to preserve these memorable moments to enjoy later. Whether it’s a exciting game highlight on YouTube, an motivating concert on YouTube, or an engaging event on Kick, knowing how to save, retain, and preserve these streams is essential for any passionate fan or content creator.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Yet the question remains: how do we make sure that our beloved livestreams are saved in high definition before they expire?&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Happily, there are countless tools and techniques accessible that make capturing and storing livestreams simpler than ever. From one-click downloaders to all-in-one backup software that takes care of everything automatically, we will delve into the best methods to preserve and store your beloved livestreams securely. Come along as we dive into the world of HD livestream preservation and find out how you can retain your cherished moments alive for decades to come.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3 id=&quot;downloadsave-and-preservestore-twitch-streamsbroadcasts&quot;&gt;Download and Store Twitch Broadcasts&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Capturing and saving Twitch broadcasts is crucial for viewers and creators alike. With the appropriate tools, you can download Twitch past broadcasts quickly in HD and save them for future enjoyment. Whether it's a exciting gaming session, a creative performance, or a live Q&amp;amp;A, ensuring you have the greatest moments stored offline is crucial. By using trustworthy downloader software, you can cut and save Twitch highlights whenever, making it easy to revisit the most thrilling parts of your favorite streams.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;One efficient way to go about this is by using a Twitch VOD recorder that allows you to transfer Twitch VODs directly to your computer in common formats like MP4. This feature allows you to securely store Twitch replays offline, ensuring you won't lose a thing when streams end. Additionally, with one-click capture options, you can easily save a copy of your Twitch streams automatically without wasting time navigating through complex processes.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Organizing downloaded content is also vital. [https://cook-frank-3.hubstack.net/analyzing-streamrecorder-whats-its-standing download twitch stream] downloader tools allow you to store and manage your VOD library effectively. You can easily archive Twitch highlights and full sessions in high quality while keeping everything sorted for quick access in the future. By preserving Twitch broadcasts, you not only create a personal collection of notable moments but also have a reliable resource to share with friends.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3 id=&quot;capturerecordsave-and-archivepreserve-youtubeyt-live-eventsstreaming-events&quot;&gt;Record and Archive YouTube Streaming Events&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;YouTube live events are a great way to interact with your beloved creators and enjoy exclusive content in real-time. Nevertheless, these streams often have a limited window for watching later, making it essential to have a reliable method for capturing and saving them. By using [https://notes.io/wAh1X StreamRecorder.io – a top choice for Twitch clip downloads] , you can effortlessly download and save these live streams in high definition, ensuring you don’t miss memorable moments, tutorials, or concerts.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;To successfully archive your preferred live events, explore tools that offer one-click download and export options for HD videos. Many of these tools allow you to record complete live sessions without the disruptions of ads, ensuring a uninterrupted viewing experience. With options to capture streams in high definition or up to 4K, you can preserve the visual quality while ensuring the content available for local viewing at any time.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;After you’ve saved your live events, it’s crucial to organize your saved content for quick access in the future. A good YouTube stream downloading tool will often have features that allow you to organize and arrange your archived videos effortlessly. By taking these steps, you can make certain that your collection of YouTube live broadcasts remains intact, allowing you to relive those exciting moments whenever you please.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3 id=&quot;universalcomprehensiveall-in-one-livestreamlive-streambroadcast-downloadingcapturedownload-solutionstools&quot;&gt;Universal Live Stream Download Solutions&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;For anyone looking to record their beloved moments from Kick, there are multiple universal downloading options that meet all your livestream needs. These solutions allow you to download streams in HD, ensuring that you keep every element of your favorite broadcasts. [https://hatesyria98.werite.net/a-comprehensive-guide-for-capturing-real-time-streams 트위치 다운로드 옵션 비교하기] offer multi-platform support, allowing both mobile and PC users to easily download and store content without the complications of complicated software.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Numerous these tools come fitted with single-click download features, enabling you to save Twitch highlights or save YouTube live broadcasts without interruption while you watch. Envision having a dependable tool that effortlessly saves your live streams, whether you're watching a gaming session or a music concert. With the tap of a button, you can transfer videos directly to your device, protect your content offline, and sort your VODs for easy access later.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;In addition to basic downloading options, some of the leading tools provide batch mode capabilities, which enable you to save entire libraries of content at the same time. This is perfect for creators or avid fans who want to store Twitch highlights, full sessions, or even Kick replays. With a priority on easy-to-use interfaces and excellent exports, these all-in-one livestream download solutions have all that you need to enhance your viewing experience and ensure that no moment goes uncaptured.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;</div></summary> <author><name>Cereallake60</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Carotid_Intimamedia_Breadth_inside_Sufferers_with_Nonalcoholic_Junk_Liver_Ailment_Going_to_the_Tertiary_Treatment_Heart_Any_Detailed_Crosssectional_Study&diff=3298552&oldid=0</id> <title>Carotid Intimamedia Breadth inside Sufferers with Nonalcoholic Junk Liver Ailment Going to the Tertiary Treatment Heart Any Detailed Crosssectional Study</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Carotid_Intimamedia_Breadth_inside_Sufferers_with_Nonalcoholic_Junk_Liver_Ailment_Going_to_the_Tertiary_Treatment_Heart_Any_Detailed_Crosssectional_Study&diff=3298552&oldid=0"/> <updated>2025-06-03T10:21:29Z</updated> <summary type="html"><p>Created page with &quot;ystematic review of predominantly level II studies, level II.PURPOSE To investigate intrarater and interrater reliability, agreement, and concurrent validity of a smartphone p...&quot;</p><p><b>New page</b></p><div>ystematic review of predominantly level II studies, level II.PURPOSE To investigate intrarater and interrater reliability, agreement, and concurrent validity of a smartphone photography-based application compared with a universal goniometer in children with cerebral palsy. METHODS Range of motion of hip abduction, popliteal angle, and ankle dorsiflexion was measured with a universal goniometer and a photography-based application in children with cerebral palsy, Gross Motor Function Classification System levels I to V.A 2-way random-effects intraclass correlation coefficients and Bland-Altman plots, standard error of measurement, and smallest detectable change were used for analyses. RESULTS The application had good to excellent reliability and concurrent validity compared with a universal goniometer, while the large measurement error of both methods suggests that changes of 10° to 23° are needed to be certain that changes over time are not results of measurement error. CONCLUSIONS A photography-based goniometer can be a reliable and valid tool when measuring range of motion in children with cerebral palsy.PURPOSE Modified ride-on cars have emerged as an early powered mobility option for young children with disabilities. The purpose of this study was to identify, extract, and synthesize perceived barriers of modified ride-on car use reported in previous studies. [https://www.selleckchem.com/products/v-9302.html selleck inhibitor] METHODS This study was descriptive using a qualitative content analysis of previously published studies identified from a systematic literature search. RESULTS Categories of perceived barriers were identified device, environmental, child-related perceived barriers regarding health, tolerance, and abilities, and caregiver-related perceived barriers regarding physical requirements, time, and motivation. Device and environmental perceived barriers were the most reported. CONCLUSIONS Pediatric physical therapists play a critical role in working with families to promote their self-efficacy for using the modified ride-on car and their capacity for overcoming the inherent difficulties associated with use. Most of the reported perceived barriers are modifiable, at least to some degree, with likely effects on modified ride-on car use.OBJECTIVE The purpose of this study was to identify the challenges physical therapists (PTs) and occupational therapists (OTs) have in providing early intervention (EI) for infants with or at risk for cerebral palsy. METHODS Therapists' responses to an open-ended question were collected via survey that was distributed to EI providers and analyzed using content analysis. RESULTS The primary self-reported barriers to PT/OT EI services had 5 themes (1) inadequate communication and collaboration, (2) challenges in coordination with family, (3) policy limitations, (4) meeting the child's individual medical needs, and (5) unequal access to resources. CONCLUSION Respondents reported that barriers are complex and exist at the individual, family, team, and societal levels. Further research is needed to explore barriers and solutions at each of these levels, from meeting a child's individual medical needs to improving interprofessional communication to increasing equitable access to resources.PURPOSE To assess the recovery likelihood, 3 to 6 years after brachial plexus birth injury (BPBI), and predict the functional recovery from integrated electromyography (IEMG). METHODS Thirty children with BPBI limited to C5-C6 lesion participated. Maximal electromyography activity of deltoid and biceps brachii was measured at entry. Shoulder and elbow functions were assessed at the baseline and at 4 intervals across 2 years. RESULTS Shoulder and elbow function significantly changed across the follow-up period. Shoulder and elbow functions were significantly dependent on deltoid and biceps brachii muscles' IEMG level, respectively, with the groups showing higher IEMG achieving better recovery. The deltoid and biceps IEMG explained a portion of the improvement in shoulder and elbow function over 2 years. CONCLUSION Recovery of the shoulder and elbow function continues 3 to 6 years after BPBI. IEMG may partially explain variation in the prognosis for children with BPBI.OBJECTIVE To describe the tip fold over rate, scalar localization, and speech perception outcomes of the CI532 Slim Modiolar Electrode. PATIENTS AND INTERVENTION All patients receiving the CI532 implant before June 2018. MAIN OUTCOME MEASURES Outcome measures for adults patients include pre- and postoperative speech perception, operative report details, electrode position as determined by X-ray and cone beam computed tomography. Comparison made with previous experience with the Contour perimodiolar electrode (CI512). In the pediatric population tip fold-over rate, measured by intraoperative X-ray, was the exclusive outcome. RESULTS One hundred twenty-five CI532 devices were implanted in adults and 69 in children. Electrode tip fold-over occurred in eight adults cases and none among children (4.1%). Cone beam CT scans of 120 out of 125 adult patients confirmed scala tympani (ST) position in all but one case where the electrode had been placed into scala vestibuli. There were no translocations from ST to scala vestibuli. This compares favorably with the CI512 translocation rate of 17%. Speech perception outcomes demonstrated good performance with mean preop phoneme scores of 16.2% (±13) increasing to 64.2% (±14) and 71.6 (±16) 3 and 12-months postop, respectively. Compared with a matched group of CI512 recipients, CI532 recipient phoneme scores were significantly higher 3 and 12-months postop by 4 and 7%, respectively. CONCLUSION The slim modiolar, CI532 electrode has provided very reliable ST position with a low rate of tip fold over. A trend toward better speech perception scores in CI532 compared with CI512 was observed.OBJECTIVE To determine short- and intermediate-term hearing preservation rates after microsurgical resection of vestibular schwannoma (VS). DATA SOURCES Systematic review of the Ovid, Cochrane, EMBASE, and Web of Science databases. STUDY SELECTION This study was restricted to full-text English-language articles detailing VS resection via the middle cranial fossa or retrosigmoid approaches. Documentation of pre- and posttreatment hearing outcomes with American Academy of Otolaryngology-Head and Neck Surgery, Gardner-Robertson, or word recognition score scales, as well as time to follow-up were required. Duplicate data sets, studies with &amp;gt;10% of patients with neurofibromatosis two, previous or nonsurgical VS treatment, case reports with less then five patients, or studies detailing decompressive surgery were excluded. DATA EXTRACTION Two authors independently performed full-text reviews to determine study eligibility. Discrepancies were settled by consensus. &quot;Class A/B, I/II&quot; hearing was defined as AAO-HNS Class A or B, Gardner-Robertson Class 1 or 2, or PTA ≤ 50 dB with word recognition score ≥ 50% on audiogram.</div></summary> <author><name>Trayring4</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Your_opioid_excessive_concept_inside_autism_range_disorders_is_it_really_worth_investigating_additional&diff=3298551&oldid=0</id> <title>Your opioid excessive concept inside autism range disorders is it really worth investigating additional</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Your_opioid_excessive_concept_inside_autism_range_disorders_is_it_really_worth_investigating_additional&diff=3298551&oldid=0"/> <updated>2025-06-03T10:21:28Z</updated> <summary type="html"><p>Created page with &quot;Chrysin (5,7-dihydroxyflavone), a nutraceutical flavonoid present in diverse plants, has a backbone structure shared with the flavone backbone, with additional hydroxyl groups...&quot;</p><p><b>New page</b></p><div>Chrysin (5,7-dihydroxyflavone), a nutraceutical flavonoid present in diverse plants, has a backbone structure shared with the flavone backbone, with additional hydroxyl groups that confers its antioxidant properties and effects at the GABAA receptor complex. However, whether these effects are due to the hydroxyl groups is unknown. Here we report the effects of chrysin or the flavone backbone (1 mg/kg) in rats subjected to the elevated plus-maze and the locomotor activity test, as well as in the zebrafish evaluated in light/dark model. Chrysin, but not flavone, increased entries and time in the open arms of the elevated plus-maze, as well as time on white compartment of the light/dark model in zebrafish. These effects were comparable to diazepam, and were devoid of motor effects in both tests, as well as in the locomotor activity test. On the other hand, flavone decreased risk assessment in the light/dark test but increased rearing in the locomotor activity test in rats, suggesting effects threat information gathering; important species differences suggest new avenues of research. It is suggested that the specific effects of chrysin in relation to flavone include more of a mechanism of action in which in addition to its action at the GABAA/benzodiazepine receptor complex also could be involved its free radical scavenging abilities, which require specific research. Preprint https//doi.org/10.1101/575514; Data and scriptshttps//github.com/lanec-unifesspa/chrysin.Carbohydrates are widely abundant molecules present in a variety of forms. For their biosynthesis and modification, nature has evolved a plethora of carbohydrate-acting enzymes. Many of these enzymes are of particular interest for biotechnological applications, where they can be used as biocatalysts or biosensors. Among the enzymes catalysing conversions of carbohydrates are the carbohydrate oxidases. These oxidative enzymes belong to different structural families and use different cofactors to perform the oxidation reaction of CH-OH bonds in carbohydrates. The variety of carbohydrate oxidases available in nature reflects their specificity towards different sugars and selectivity of the oxidation site. Thanks to their properties, carbohydrate oxidases have received a lot of attention in basic and applied research, such that nowadays their role in biotechnological processes is of paramount importance. In this review we provide an overview of the available knowledge concerning the known carbohydrate oxidases. The oxidases are first classified according to their structural features. After a description on their mechanism of action, substrate acceptance and characterisation, we report on the engineering of the different carbohydrate oxidases to enhance their employment in biocatalysis and biotechnology. In the last part of the review we highlight some practical applications for which such enzymes have been exploited.Gold nanoparticles (AuNPs) are gaining a lot of attention in recent decades from researchers due to their unique optoelectronic properties and their significance in the field of biomedicine. Keeping this in view, our research work was designed to investigate gold nanoparticles obtained by using a fungal endophytic strain Chaetomium globosum, isolated from Vitex negundo which showed significant activity on enzyme inhibition. In the present study, the fungal isolate C. globosum was characterized using HPLC and LC-MS. A novel compound Catechin was matched with standard Catechin. Further, the endophyte C. globosum extract was utilized to synthesize gold nanoparticles (CgAuNPs) which was analysed by UV-visible spectroscopy. The CgAuNPs exhibited wine red color and the absorption peak appeared at 542 nm confirming the formation of the AuNPs. Further, Fourier Transmission Infrared Spectroscopy (FTIR) was performed to confirm the various functional groups present in mycosynthesized CgAuNPs. FTIR analysis demonstrated the presence of amines, flavonoids, as well as the presence of amide I linkage which possibly reduces Au+ to Au0. The synthesized CgAuNPs exhibited potential cytotoxicity against HeLa cells in a dose dependent manner. Further, CgAuNPs demonstrated significant anti-inflammatory activity. Overall, the present work provides insights into the design of nano delivery and may be applied for clinical studies in future.We describe herein a simple procedure for quantifying endospore abundances in ancient and organic-rich permafrost. We repeatedly (10x) extracted and fractionated permafrost using a tandem filter assembly composed of 3 and 0.2 μm filters. [https://www.selleckchem.com/products/pf-06882961.html Danuglipron] Then, the 0.2 μm filter was washed (7x), autoclaved, and the contents eluted, including dipicolinic acid (DPA). Time-resolved luminescence using Tb(EDTA) yielded a LOD of 1.46 nM DPA (6.55 × 103 endospores/mL). In review, DPA/endospore abundances were ~2.2-fold greater in older 33 ky permafrost (258 ± 36 pmol DPA gdw-1; 1.15 × 106 ± 0.16 × 106 spores gdw-1) versus younger 19 ky permafrost (p = 0.007297). This suggests that dormancy increases with permafrost age.Vaccines that induce cytotoxic T lymphocyte (CTL)-mediated immune responses constitute an important class of medical tools to fend off diseases like infections and malignancy. Epitope peptides, as a format of CTL vaccines, are being tested preclinically and clinically. To elicit CTL responses, epitope vaccines go through an epitope presentation pathway in dendritic cells (DCs) that has multiple bottleneck steps and hence is inefficient. Here, we report the development of a strategy to overcome one of these barriers, phagolysosomal escape in DCs. First, we furnished a previously established carrier-an immune-tolerant elastin-like polypeptide nanoparticle (iTEP NP)-with the peptides that are derived from the DNA polymerase of herpes simplex virus 1 (Pol peptides). Pol peptides were reported to facilitate phagolysosomal escape. In this study, while we found that Pol peptides promoted the CTL epitope presentation; we also discovered Pol peptides disrupted the formation of the iTEP NP. Thus, we engineered a series of new iTEPs and identified several iTEPs that could accommodate Pol peptides and maintain their NP structure at the same time. We next optimized one of these NPs so that its stability is responsive to its redox environment. This environment-responsive NP further strengthened the CTL epitope presentation and CTL responses. Lastly, we revealed how this NP and Pol peptides utilized biological cues of phagolysosomes to realize phagolysosomal escape and epitope release. In summary, we developed iTEP NP carriers with a new phagolysosomal escape function. These carriers, with their priorly incorporated functions, resolve three bottleneck issues in the CTL epitope presentation pathway vaccine uptake, phagolysosomal escape, and epitope release.</div></summary> <author><name>Bitemitten6</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Mcguirestein6013</id> <title>User:Mcguirestein6013</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Mcguirestein6013"/> <updated>2025-06-03T10:21:27Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Mcguirestein6013&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Mcguirestein6013 (page does not exist)"><bdi>Mcguirestein6013</bdi></a> was created</p></summary> <author><name>Mcguirestein6013</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=User_talk:Goldwin678&diff=3298550&oldid=0</id> <title>User talk:Goldwin678</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=User_talk:Goldwin678&diff=3298550&oldid=0"/> <updated>2025-06-03T10:21:27Z</updated> <summary type="html"><p>Created page with &quot;GOLDWIN678 adalah penyedia game online terkemuka yang menawarkan pengalaman bermain seru dengan fitur super scatter dan peluang jackpot maxwin setiap hari. https://goldwin678....&quot;</p><p><b>New page</b></p><div>GOLDWIN678 adalah penyedia game online terkemuka yang menawarkan pengalaman bermain seru dengan fitur super scatter dan peluang jackpot maxwin setiap hari.<br />https://goldwin678.io/<br /><br /><br />https://www.youtube.com/@goldwin678io<br />https://x.com/goldwin678io<br />https://www.tumblr.com/goldwin678io<br />https://www.twitch.tv/goldwin678io/about<br />https://www.instapaper.com/p/16410073<br />https://soundcloud.com/goldwin678-601642716<br />https://www.blogger.com/profile/17084629684495983274<br />https://www.behance.net/goldwin678io<br />https://os.mbed.com/users/goldwin678io/<br 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/>https://nhattao.com/members/user6759672.6759672/<br />https://careers.gita.org/profiles/6703282-goldwin678-io<br />https://fairebruxellessamen.be/profiles/goldwin678/activity<br />https://www.malikmobile.com/26d2486f8<br />https://www.aicrowd.com/participants/goldwin678<br />https://anyflip.com/homepage/htyob#About<br />https://qa.laodongzu.com/?qa=user/goldwin678<br />https://www.clickasnap.com/profile/goldwin678<br />https://gitee.com/goldwin678io<br />https://hypothes.is/users/goldwin678io<br />https://www.question-ksa.com/user/goldwin678<br />https://www.wvhired.com/profiles/6703339-goldwin678-io<br />https://www.investagrams.com/Profile/goldwin678<br />https://tatoeba.org/en/user/profile/goldwin678<br />https://hashnode.com/@goldwin678io<br />https://www.blockdit.com/goldwin678<br />https://activepages.com.au/profile/goldwin678io<br />https://skitterphoto.com/photographers/618854/goldwin678-io<br />https://co-roma.openheritage.eu/profiles/goldwin678/activity<br />https://justpaste.it/u/goldwin678io<br />https://www.intensedebate.com/people/goldwin678io<br />https://www.metooo.es/u/goldwin678io<br />https://www.miseducationofmotherhood.com/profile/goldwin678io46248/profile<br />https://www.ohay.tv/profile/goldwin678io<br />https://www.fitday.com/fitness/forums/members/goldwin678.html<br />https://www.popdaily.com.tw/user/470832<br />https://www.remoteworker.co.uk/profiles/6703392-goldwin678-io<br />https://ask.banglahub.com.bd/user/goldwin678<br />https://estar.jp/users/1865455767<br />https://www.humanart.cz/portfolio/goldwin678/<br />https://www.1001fonts.com/users/goldwin678-io/<br />https://goldwin678.stck.me/profile<br />https://protocol.ooo/ja/users/goldwin678-io<br />https://rebrickable.com/users/goldwin678/mocs/photos/<br />https://www.adpost.com/u/goldwin678/<br />https://war-lords.net/forum/user-49562.html<br />https://gov.trava.finance/user/goldwin678<br />https://pumpyoursound.com/u/user/1499271<br 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/>https://belgaumonline.com/profile/012a7e2d6e350a7ca98e33cbed8be478/<br />https://code.getnoc.com/goldwin678io<br />http://www.hot-web-ads.com/view/item-16049277-GOLDWIN678.html<br />https://participationcitoyenne.rillieuxlapape.fr/profiles/goldwin678/activity<br />https://anunt-imob.ro/user/profile/811632<br />https://akwatik.com/goldwin678<br />https://matters.town/@goldwin678io<br />https://seomotionz.com/member.php?action=profile&amp;uid=69114<br />https://tinhte.vn/members/goldwin678io.3322229/<br />https://fewpal.com/edf3203a7<br />https://shareyoursocial.com/goldwin678<br />https://www.flyingpepper.in/profile/goldwin678io49239/profile<br />https://substance3d.adobe.com/community-assets/profile/org.adobe.user:D8C72229683EA5640A495E28@AdobeID<br />https://onlyfans.com/u503311514<br />https://www.tenormadness.com/profile/goldwin678io82279/profile</div></summary> <author><name>Goldwin678</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Styles_and_Predictors_of_Tv_Watching_along_with_Computer_Employ_Between_Females_Residing_in_Socioeconomically_Deprived_Communities_A_potential_Cohort_Study&diff=3298549&oldid=0</id> <title>Styles and Predictors of Tv Watching along with Computer Employ Between Females Residing in Socioeconomically Deprived Communities A potential Cohort Study</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Styles_and_Predictors_of_Tv_Watching_along_with_Computer_Employ_Between_Females_Residing_in_Socioeconomically_Deprived_Communities_A_potential_Cohort_Study&diff=3298549&oldid=0"/> <updated>2025-06-03T10:21:20Z</updated> <summary type="html"><p>Created page with &quot;The quality standards established based on the research results were specific and repeatable, and suitable for the quality evaluation of Alismatis Rhizoma. We recommended that...&quot;</p><p><b>New page</b></p><div>The quality standards established based on the research results were specific and repeatable, and suitable for the quality evaluation of Alismatis Rhizoma. We recommended that the botanical sources, TLC examination, alcohol-soluble extract of salt prepared slices and content determination should be revised in the Ch. P 2020 edition.Ten compounds, including nucleosides and amino acids were identified by UPLC-Q-TOF-MS. HPLC fingerprints on these compounds in Alismatis Rhizoma were established for the first time. The comparisons of Alismatis Rhizoma from different regions were conducted by the similarity evaluation and hierarchical cluster analysis(HCA). Meanwhile, the HPLC-DAD method for the content determination of five nucleosides was also established. The results showed that the similarities of Alismatis Rhizoma collected from Sichuan and Fujian provinces were above 0.96, whereas they were less than 0.87 in those from Guangxi province. The results of HCA showed the samples from Sichuan and Fujian were gathered in the same group, all samples from Guangxi in another group, which indicated the similarities between samples from Sichuan and Fujian in nucleosides and they were different from the samples from Guangxi. The total contents of five nucleosides were revealed, of which samples from Sichuan and Fujian were 0.81-1.30 mg·g~(-1) followed a descending order of vernine&amp;gt;cytidine&amp;gt;uridine&amp;gt;adenine&amp;gt;adenosine, and from Guangxi were 0.35-0.50 mg·g~(-1) with the sequences of uridine&amp;gt;adenine&amp;gt;vernine&amp;gt;cytidine&amp;gt;adenosine. The nucleosides contents of samples from Sichuan and Fujian were both higher than that from Guangxi. For samples from Sichuan and Fujian, the former was slightly higher, except for adenine. These results would be helpful to reveal the bioactive constituents in aqueous extract and provided important evidences for the quality control of Alismatis Rhizoma.An ultra-performance liquid chromatography(UPLC) method integrating characteristic chromatogram and eight terpenoids determination has been established for comparing the differences of Alismatis Rhizoma(Zexie) from different product areas. Thirty-seven batches of crude drugs and thirty batches of prepared slices of Alismatis Rhizoma were analyzed. The obtained data were analyzed by similarity evaluation, principal components analysis(PCA) and partial least squares discriminant analysis(PLS-DA). There were three main characteristic peaks in the characteristic chromatograms, and alisol B 23-acetate(S) was selected as the reference. Compared with the S peak, the relative retention times of the other two characteristic peaks were 0.55(alisol) and 0.77(alisol B), respectively. Peak areas and the ratio of alisol B to alisol B 23-acetate could be used to distinguish Alismatis Rhizoma from different geographical origins. The samples were divided into three groups by PCA and PLS-DA based on the content determination rontrol of Alismatis Rhizoma.Alismatis Rhizoma(Zexie) is a commonly used traditional Chinese medicine, and it is separated into &quot;Chuan Zexie&quot;(Sichuan and Hubei provinces), &quot;Jian Zexie&quot;(Fujian and Jiangxi provinces) and &quot;Guang Zexie&quot;(Guangxi province) according to different producing areas. [https://www.selleckchem.com/products/pentamidine.html https://www.selleckchem.com/products/pentamidine.html] Alisma plantago-aquatica and A. orientale were listed as the original plants of Alismatis Rhizoma in different editions of Chinese Pharmacopoeia(Ch.P), respectively. The botanical origins of Alismatis Rhizoma caused much controversy during a period of time. This study aimed to define the botanical origins of Alismatis Rhizoma from different producing areas, and supply scientific evidence for Ch. P 2020 edition. In this paper, we summarized the descriptions of original plants and producing areas of Alismatis Rhizoma in ancient literatures. Flowers and fruits of original plants of Alismatis Rhizoma were collected from different typical areas, and compared with the morphological description of two species from Alisma genus in the Flora of China. Thirty-nine batches of leaves from 8 different areas were identified using DNA barcoding technology. The results showed that original plants of Alismatis Rhizoma from different areas could be distinguished from each other based on morphological characteristics and molecular characteristics. Then, &quot;Jian Zexie&quot; was identified as A. orientale, while &quot;Chuan Zexie&quot; and &quot;Guang Zexie&quot; were identified as A. plantago-aquatica. In conclusion, combining with herbal textural research, morphologic characteristics, DNA barcoding technology and market situation, this paper recommended that the botanical sources of Alismatis Rhizoma could be revised as Alisma orientale(Sam.) Juzep. and Alisma plantago-aquatica Linn. in the Ch. P 2020 edition.It is an essential task to discuss the death cases for clinicians. During the emergent public events, the report and analysis of death cases is of far-reaching significance. The epidemic of coronavirus disease 2019(COVID-19) has brought huge losses to China, and the medical system has been sustaining tremendous pressure. The best weapon to defeat the epidemic is medical data and related scientific research, of which the systematic analysis and efficient use of death cases is a key step. Based on the incomplete record of death case report, the lack of humanistic perspective and patient report, every department and institution is facing great challenge in terms of data management. Given that the relevant systems need to be improved, and that the integration of standardized reports and clinical research is not mature,as well as other problems, we put forward several methodological suggestions ① Establish national medical and health data center and improve relevant laws and regulations. ② Increase investment in medical data management and start data collection and analysis as early as possible during the epidemic. ③ Refine the content of death case report and promote the standardization of report. ④ Pay close attention to the report of death cases, review, summary and analysis. More importantly, we should continue to build and improve platforms and programs related to disease control, carry out epidemic-associated scientific research, enhance the managing efficiency of public health data, elevate the anti-risk capability of our medical system, and promote the steady progress of the health China strategy.</div></summary> <author><name>Tailorepoxy21</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:LoriHerrington</id> <title>User:LoriHerrington</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:LoriHerrington"/> <updated>2025-06-03T10:21:20Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:LoriHerrington&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:LoriHerrington (page does not exist)"><bdi>LoriHerrington</bdi></a> was created</p></summary> <author><name>LoriHerrington</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Clonotypic_architecture_of_an_Gagspecific_CD8_Tcell_reaction_inside_longterm_individual_HIV2_contamination&diff=3298548&oldid=0</id> <title>Clonotypic architecture of an Gagspecific CD8 Tcell reaction inside longterm individual HIV2 contamination</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Clonotypic_architecture_of_an_Gagspecific_CD8_Tcell_reaction_inside_longterm_individual_HIV2_contamination&diff=3298548&oldid=0"/> <updated>2025-06-03T10:21:18Z</updated> <summary type="html"><p>Created page with &quot;arriers, and optimize safety and adherence for telehealth interventions involving activities in weightbearing or standing positions.&lt;br /&gt;&lt;br /&gt;The COVID-19 pandemic has neces...&quot;</p><p><b>New page</b></p><div>arriers, and optimize safety and adherence for telehealth interventions involving activities in weightbearing or standing positions.&lt;br /&gt;&lt;br /&gt;The COVID-19 pandemic has necessitated a rapid shift to telerehabilitation services for people with stroke, but there is little evidence to guide best practice. Our review provides practical guidance and strategies to overcome barriers, and optimize safety and adherence for telehealth interventions involving activities in weightbearing or standing positions.&lt;br /&gt;&lt;br /&gt; Frailty severity may be an important determinant for impaired recovery after cervical spine deformity (CD) corrective surgery.&lt;br /&gt;&lt;br /&gt; To evaluate postop clinical recovery among CD patients between frailty states undergoing primary procedures.&lt;br /&gt;&lt;br /&gt; Patients &amp;gt;18yr old undergoing surgery for CD with health-related quality of life (HRQL) data at baseline, 3-mo, and 1-yr postoperative were identified. Patients were stratified by the modified CD frailty index scale from 0 to 1 (no frailty [NF] &amp;lt;0.3,mild/severe fraily [F] &amp;gt;0.3).Patients in NF and F groups were propensity score matched for TS-CL (T1 slope [TS] minus angle between the C2 inferior end plate and the C7 inferior end plate [CL]) to control for baseline deformity. Area under the curve was calculated for follow-up time intervals determining overall normalized, time-adjusted HRQL outcomes; Integrated Health State (IHS) was compared between NF and F groups.&lt;br /&gt;&lt;br /&gt; A total of 106 CD patients were included (61.7 yr, 66% F, 27.7 kg/m2)-byfrailtygroup52.8% NF, 47.2overall health state compared to baseline disability. This signifies that with frailty severity, patients have more room for improvement postop compared to baseline quality of life.While the American Physical Therapy Association has upheld a code of ethics since 1935, the philosophical underpinnings of physical therapist practice have yet to be robustly explicated. Theoretical work in the field of philosophy of medicine can be engaged to study physical therapist practice. Modifying the phenomenological and teleological framework of Edmund Pellegrino, a physician and prominent bioethicist, the purpose of this theoretical paper is to particularize Pellegrino's philosophy of medicine to construct an internal morality of physical therapy. Acknowledging that the internal morality of health care professions is founded in the relationship between a patient and a health care professional, this paper analyzes the nature and telos, or end, of physical therapy through 3 phenomena of physical therapy-the fact of disability, the act of profession, and the act of physical therapy. This paper claims that, rather than medicine's clinical truth of a good treatment decision, physical therapy's clinical truth is a good process that capacitates patients. This relational approach to an internal morality robustly underpins a philosophy and ethics of physical therapy.&lt;br /&gt;&lt;br /&gt; Telerehabilitation is an option that should be adapted as soon as possible to face the crisis caused by coronavirus disease 2019. An umbrella and mapping review with meta-meta-analysis (MMA) of the available scientific evidence was performed to determine whether telerehabilitation could be an effective alternative to conventional rehabilitation in physical therapist practice.&lt;br /&gt;&lt;br /&gt; A systematic review of reviews and a synthesis of the findings of all systematic evidence published to date with a visual map and a meta-meta-analysis (MMA) were performed. A systematic search was realized in Cochrane Database of Systematic Reviews, MEDLINE (PubMed), and Google Scholar. Two independent reviewers performed a data analysis and assessed the quality of the included reviews, assessing the risk of bias using ROBIS.&lt;br /&gt;&lt;br /&gt; Twenty-nine articles that met the inclusion criteria were selected and divided according to the type of patient targeted for rehabilitation (patients with cardiorespiratory, musculoskeletal, and neurological case 2019 era.Predicting tree frost tolerance is critical to select adapted species according to both the current and predicted future climate. The relative change in water to carbohydrate ratio is a relevant trait to predict frost acclimation in branches from many tree species. The objective of this study is to demonstrate the interspecific genericity of this approach across nine tree species. In the studied angiosperm species, frost hardiness dynamics were best correlated to a decrease in water content at the early stage of acclimation (summer and early autumn). Subsequently, frost hardiness dynamics were more tightly correlated to soluble carbohydrate contents until spring growth resumption. Based on different model formalisms, we predicted frost hardiness at different clade levels (angiosperms, family, genus and species) with high to moderate accuracy (1.5-6.0°C RMSE) and robustness (2.8-6.1°C RMSEP). The TOT model, taking all soluble carbohydrate and polyols into account, was more effective and adapted for large scale studies aiming to explore frost hardiness across a wide range of species. The ISC model taking the individual contribution of each soluble carbohydrate molecule into account was more efficient at finer scale such as family or species. The ISC model performance also suggests that the role of solutes cannot be reduced to a 'bulk' osmotic effect as could be computed if all of them were located in a single, common, compartment. This study provides sets of parameters to predict frost hardiness in a wide range of species, and clues in targeting specific carbohydrate molecules to improve frost hardiness.In recent correspondences, authors emphasized the need to consider vulnerable groups such as migrants, refugees, prisoners, and persons with disabilities in the interventions and plans of government and health authorities in combatting coronavirus disease 2019 (COVID-19). [https://www.selleckchem.com/products/at-406.html https://www.selleckchem.com/products/at-406.html] This paper discusses the urgent call for government and health authorities to ensure that indigenous peoples, being distinct ethnic communities, are included in the rolling out of COVID-19 vaccines with considerations to their unique culture, beliefs and traditions.&lt;br /&gt;&lt;br /&gt; Cardiovascular diseases (CVDs) increase mortality risk from coronavirus infection (COVID-19). There are also concerns that the pandemic has affected supply and demand of acute cardiovascular care. We estimated excess mortality in specific CVDs, both 'direct', through infection, and 'indirect', through changes in healthcare.&lt;br /&gt;&lt;br /&gt; We used (i) national mortality data for England and Wales to investigate trends in non-COVID-19 and CVD excess deaths; (ii) routine data from hospitals in England (n = 2), Italy (n = 1), and China (n = 5) to assess indirect pandemic effects on referral, diagnosis, and treatment services for CVD; and (iii) population-based electronic health records from 3862012 individuals in England to investigate pre- and post-COVID-19 mortality for people with incident and prevalent CVD. We incorporated pre-COVID-19 risk (by age, sex, and comorbidities), estimated population COVID-19 prevalence, and estimated relative risk (RR) of mortality in those with CVD and COVID-19 compared with CVD and non-infected (RR 1.</div></summary> <author><name>Coldtax5</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Tienne_Geoffroy_SaintHilaire_like_a_predecessor_in_the_epigenetic_idea_of_progression&diff=3298547&oldid=0</id> <title>Tienne Geoffroy SaintHilaire like a predecessor in the epigenetic idea of progression</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Tienne_Geoffroy_SaintHilaire_like_a_predecessor_in_the_epigenetic_idea_of_progression&diff=3298547&oldid=0"/> <updated>2025-06-03T10:21:15Z</updated> <summary type="html"><p>Created page with &quot;Recent research indicates that most tissue and cell types can secrete and release membrane-enclosed small vesicles, known as exosomes, whose content reflects the physiological...&quot;</p><p><b>New page</b></p><div>Recent research indicates that most tissue and cell types can secrete and release membrane-enclosed small vesicles, known as exosomes, whose content reflects the physiological/pathological state of the cells from which they originate. These exosomes participate in the communication and cell-to-cell transfer of biologically active proteins, lipids, and nucleic acids. Studies of RNA viruses have demonstrated that exosomes release regulatory factors from infected cells and deliver other functional host genetic elements to neighboring cells, and these functions are involved in the infection process and modulate the cellular responses. This review provides an overview of the biogenesis, composition, and some of the most striking functions of exosome secretion and identifies physiological/pathological areas in need of further research. While initial indications suggest that exosome-mediated pathways operate in vivo, the exosome mechanisms involved in the related effects still need to be clarified. The current review focuses on the role of exosomes in RNA virus infections, with an emphasis on the potential contributions of exosomes to pathogenesis.Wireless Sensor Networks constitute an important part of the Internet of Things, and in a similar way to other wireless technologies, seek competitiveness concerning savings in energy consumption and information availability. [https://www.selleckchem.com/products/amg-487.html see more] These devices (sensors) are typically battery operated and distributed throughout a scenario of particular interest. However, they are prone to interference attacks which we know as jamming. The detection of anomalous behavior in the network is a subject of study where the routing protocol and the nodes increase power consumption, which is detrimental to the network's performance. In this work, a simple jamming detection algorithm is proposed based on an exhaustive study of performance metrics related to the routing protocol and a significant impact on node energy. With this approach, the proposed algorithm detects areas of affected nodes with minimal energy expenditure. Detection is evaluated for four known cluster-based protocols PEGASIS, TEEN, LEACH, and HPAR. The experiments analyze the protocols' performance through the metrics chosen for a jamming detection algorithm. Finally, we conducted real experimentation with the best performing wireless protocols currently used, such as Zigbee and LoRa.Natural social systems within animal groups are an essential aspect of agricultural optimization and livestock management strategy. Assessing elements of animal behaviour under domesticated conditions in comparison to natural behaviours found in wild settings has the potential to address issues of animal welfare effectively, such as focusing on reproduction and production success. This review discusses and evaluates to what extent social network analysis (SNA) can be incorporated with sensor-based data collection methods, and what impact the results may have concerning welfare assessment and future farm management processes. The effectiveness and critical features of automated sensor-based technologies deployed in farms include tools for measuring animal social group interactions and the monitoring and recording of farm animal behaviour using SNA. Comparative analyses between the quality of sensor-collected data and traditional observational methods provide an enhanced understanding of the behavioural dynamics of farm animals. The effectiveness of sensor-based approaches in data collection for farm animal behaviour measurement offers unique opportunities for social network research. Sensor-enabled data in livestock SNA addresses the biological aspects of animal behaviour via remote real-time data collection, and the results both directly and indirectly influence welfare assessments, and farm management processes. Finally, we conclude with potential implications of SNA on modern animal farming for improvement of animal welfare.Bruton tyrosine kinase (BTK) inhibitors have become an important therapy for untreated and previously treated patients with chronic lymphocytic leukemia (CLL). Despite improved outcomes, rare adverse events, such as invasive fungal infections, have been reported with the use of first-generation BTK inhibitors. Invasive fungal infections carry a high morbidity and mortality risk. There have been several case reports describing the association between aspergillosis and ibrutinib treatment, but none with acalabrutinib, to our knowledge. In this case report, we describe a patient with CLL who developed an intracranial Aspergillus fumigatus infection while receiving acalabrutinib.&lt;br /&gt;&lt;br /&gt; Lead-associated complications and technical issues in patients with cardiac implantable electronic devices are common but underreported in the literature.&lt;br /&gt;&lt;br /&gt; All patients undergoing implantation of the Osypka QT-5&lt;br /&gt;&lt;br /&gt; ventricular lead at the University Clinic St. Pölten between 1 January 2006 and 31 December 2012 were retrospectively analyzed (&lt;br /&gt;&lt;br /&gt; = 211). Clinical data including pacemaker follow-up examinations and the need for lead revisions were assessed. Kaplan-Meier analysis to estimate the rate of lead dysfunction during long-term follow-up was conducted.&lt;br /&gt;&lt;br /&gt; Patients were followed for a median of 5.2 years (interquartile range (IQR) 2.0-8.7). R-wave sensing properties at implantation, compared to last follow-up, remained basically unchanged 9.9 mV (IQR 6.8-13.4) and 9.6 mV (IQR 5.6-12.0), respectively). Ventricular pacing threshold significantly increased between implantation (0.5 V at 0.4 ms; IQR 0.5-0.8) and the first follow-up visit (1.0 V at 0.4 ms; IQR 0.8-1.3; &lt;br /&gt;&lt;br /&gt; &amp;lt; 0.001) and this increase persisted throughout to the last check-up (0.9 V at 0.4 ms; IQR 0.8-1.2). Impedance significantly declined from 1142 Ω (IQR 955-1285) at implantation to 814 Ω (IQR 701-949; &lt;br /&gt;&lt;br /&gt; &amp;lt; 0.001) at the first check-up, followed by a further decrease to 450 Ω (IQR 289-652; &lt;br /&gt;&lt;br /&gt; &amp;lt; 0.001) at the last check-up. Overall, the Osypka QT-5&lt;br /&gt;&lt;br /&gt; ventricular lead was replaced in 36 patients (17.1%).&lt;br /&gt;&lt;br /&gt; This report shows an unexpected high rate of technical issues of the Osypka QT-5&lt;br /&gt;&lt;br /&gt; ventricular lead during long-term follow-up.&lt;br /&gt;&lt;br /&gt;This report shows an unexpected high rate of technical issues of the Osypka QT-5® ventricular lead during long-term follow-up.</div></summary> <author><name>Kevinmallet0</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=How_The_10_Worst_Bunk_Bed_Mistakes_Of_All_Time_Could_Have_Been_Prevented&diff=3298546&oldid=0</id> <title>How The 10 Worst Bunk Bed Mistakes Of All Time Could Have Been Prevented</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=How_The_10_Worst_Bunk_Bed_Mistakes_Of_All_Time_Could_Have_Been_Prevented&diff=3298546&oldid=0"/> <updated>2025-06-03T10:21:14Z</updated> <summary type="html"><p>Created page with &quot;&lt;h2&gt;A Comprehensive Guide to Children&#039;s [https://telegra.ph/The-Reasons-Best-Rated-Bunk-Beds-Is-More-Difficult-Than-You-Imagine-06-03-2 Bunk Beds] : Styles, Benefits, and Safe...&quot;</p><p><b>New page</b></p><div>&lt;h2&gt;A Comprehensive Guide to Children's [https://telegra.ph/The-Reasons-Best-Rated-Bunk-Beds-Is-More-Difficult-Than-You-Imagine-06-03-2 Bunk Beds] : Styles, Benefits, and Safety Considerations&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Bunk beds have actually ended up being a popular option for families seeking to make the most of space and provide an enjoyable sleeping environment for kids. With their special style, they offer an innovative and useful solution for shared bed rooms, playrooms, or perhaps guest accommodation. This short article explores the different styles of kids's bunk beds, their benefits, security factors to consider, and addresses some regularly asked concerns.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h2&gt;The Allure of [https://buzzinguniverse.com/members/robertbubble0/activity/348161/ Bunk Bed] s&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Children's bunk beds are more than simply space-saving structures; they are likewise an entrance to adventurous dreams and creative play. Below is an in-depth examination of their various advantages.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;Advantages of [https://notes.io/wAhgp Bunk Beds] &lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;ol&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Space-Saving&lt;/strong&gt;: Bunk beds effectively utilize vertical space, making them a perfect option for smaller sized spaces.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Playful Design&lt;/strong&gt;: Many bunk bed styles include slides, camping tents, and themed components, sparking imagination and excitement.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Partner Sharing&lt;/strong&gt;: Bunk beds are perfect for siblings sharing a space or accommodating slumber parties.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Versatile Use&lt;/strong&gt;: Some models can be separated into two individual beds, using versatility as kids grow.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Storage Options&lt;/strong&gt;: Many bunk beds come with integrated drawer storage or shelves, further enhancing their practicality.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt;&lt;/ol&gt;&lt;br /&gt;&lt;br /&gt;&lt;h2&gt;Designs of Children's Bunk Beds&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;The range of bunk beds readily available today accommodates different choices and requirements. Below is a summary of some popular designs.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;table&gt; &lt;br /&gt;&lt;br /&gt; &lt;thead&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;th&gt;&lt;strong&gt;Design&lt;/strong&gt;&lt;/th&gt; &lt;br /&gt;&lt;br /&gt; &lt;th&gt;&lt;strong&gt;Description&lt;/strong&gt;&lt;/th&gt; &lt;br /&gt;&lt;br /&gt; &lt;th&gt;&lt;strong&gt;Best For&lt;/strong&gt;&lt;/th&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;/thead&gt; &lt;br /&gt;&lt;br /&gt; &lt;tbody&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;&lt;strong&gt;Standard Bunk Bed&lt;/strong&gt;&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;A conventional style including one bed stacked above another.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Brother or sisters sharing a space.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;&lt;strong&gt;Loft Bed&lt;/strong&gt;&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Comparable to a bunk bed without the bottom bunk, permits a workspace or play location below.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Minimal space for play/desk.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;&lt;strong&gt;L-Shaped Bunk Bed&lt;/strong&gt;&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;2 beds arranged in an L-shape, frequently with extra areas for storage or play.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Special space designs.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;&lt;strong&gt;Twin Over Full&lt;/strong&gt;&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;A twin bed over a complete bed, accommodating various sleep needs.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Growing kids and teens.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;&lt;strong&gt;High Sleeper&lt;/strong&gt;&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Stands even higher than a loft bed, typically featuring a desk or play location listed below.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Older kids requiring more play/desk space.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;&lt;strong&gt;Camping Tent Bunk Bed&lt;/strong&gt;&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Bunk beds with a canopy or tent-like structure, producing a cozy, enjoyable space.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;td&gt;Active and imaginative kids.&lt;/td&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tr&gt; &lt;br /&gt;&lt;br /&gt; &lt;/tbody&gt;&lt;br /&gt;&lt;br /&gt;&lt;/table&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;Key Features to Consider&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;When choosing the right bunk bed for kids, the following features deserve considering:&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;ul&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Material&lt;/strong&gt;: Bunk beds can be made from wood, metal, or a combination. Each has its unique visual and toughness.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Weight Capacity&lt;/strong&gt;: Always validate the weight limitation of the bunk bed to ensure it can accommodate your kids safely.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Safety Rails&lt;/strong&gt;: Ensure the top bunk has durable rails to prevent falls.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Ladder Security&lt;/strong&gt;: A well-designed ladder ought to offer simple and safe access to the upper bunk.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Completing&lt;/strong&gt;: Ensure any surfaces are non-toxic and safe for children.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt;&lt;/ul&gt;&lt;br /&gt;&lt;br /&gt;&lt;h2&gt;Safety Considerations&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Safety is critical when it comes to kids's bunk beds. The following standards need to be adhered to:&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;ol&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Age Appropriateness&lt;/strong&gt;: Generally, children under six years of ages need to not oversleep the upper bunk due to security dangers.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Durable Construction&lt;/strong&gt;: Ensure the frame and products are solid and can support the weight without sagging.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Regular Maintenance&lt;/strong&gt;: Periodically look for loose screws, bolts, or other parts that might need tightening.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Clear Play Area&lt;/strong&gt;: Keep the location around the bunk bed devoid of toys and challenges to minimize tripping dangers.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt;&lt;/ol&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;Setting Rules for Safe Use&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Developing standards for bunk bed use will help ensure security:&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;ul&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Limit Jumping and Climbing&lt;/strong&gt;: Children must be recommended against jumping from the top bunk and getting on the sides.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Monitoring Sleepovers&lt;/strong&gt;: Monitor young visitors while they are using the bunk bed for the very first time.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;li&gt;&lt;strong&gt;Educate on Ladder Use&lt;/strong&gt;: Teach how to use the ladder safely, stressing the significance of dealing with the ladder when going up or down.&lt;/li&gt;&lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt; &lt;br /&gt;&lt;br /&gt;&lt;/ul&gt;&lt;br /&gt;&lt;br /&gt;&lt;h2&gt;Frequently Asked Questions&lt;/h2&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;1. What age is proper for a kid to oversleep the leading bunk?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Many makers advise that kids should be at least six years old to sleep in the upper bunk. This standard is designed to alleviate the risk of falls.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;2. Can bunk beds be tailored?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Yes, lots of manufacturers use adjustable alternatives, including colors, materials, and additional features like drawers or desks.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;3. Are bunk beds safe for weight?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Bunk beds have weight limitations, usually ranging from 200 to 400 pounds, depending upon the model and material. Always inspect the maker's requirements.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;4. How do I preserve and clean a bunk bed?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Frequently inspect for loose parts, keep the bed clean by wiping down surface areas, and make sure the bedding is fresh to promote a safe and hygienic sleep environment.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3&gt;5. Can bunk beds be separated into specific beds?&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Lots of bunk beds include a choice to separate them into 2 private beds, offering long-term versatility.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Children's bunk beds are more than mere furnishings; they are a functional, flexible, and creative element of a kid's space. With various styles offered and numerous security considerations to bear in mind, parents can choose the perfect bed that fits their space, meets their kids's requirements, and instills a sense of adventure. By comprehending the advantages, designs, and precaution connected with bunk beds, families can develop a wonderful and safe sleeping environment for their kids. Whether for brother or sisters sharing a space or space-saving services, bunk beds remain a precious choice for numerous households.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;</div></summary> <author><name>Robertbubble0</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Nhng_L_Do_Gip_StreamRecorderio_Tr_Thnh_Cng_C_Ti_c_c_Yu_Thch&diff=3298545&oldid=0</id> <title>Nhng L Do Gip StreamRecorderio Tr Thnh Cng C Ti c c Yu Thch</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Nhng_L_Do_Gip_StreamRecorderio_Tr_Thnh_Cng_C_Ti_c_c_Yu_Thch&diff=3298545&oldid=0"/> <updated>2025-06-03T10:21:09Z</updated> <summary type="html"><p>Created page with &quot;&lt;p&gt;Trong thời kỳ thế giới số hóa hiện nay, việc tải về cùng ghi âm các video trên mạng trở nên một cần thiết cho nhiều người đối vớ...&quot;</p><p><b>New page</b></p><div>&lt;p&gt;Trong thời kỳ thế giới số hóa hiện nay, việc tải về cùng ghi âm các video trên mạng trở nên một cần thiết cho nhiều người đối với nhiều người dùng. 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Mặc dù thế, với những lợi ích mà StreamRecorder.io mang lại, rất nhiều người cho rằng đây vẫn một trong số công cụ tốt nhất để ghi lại và tải xuống những video online trong năm 2025.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3 id=&quot;so-sánhso-sánhso-sánh-streamrecorderiostream-recorderio-vớivới-cácso-với-cácnhững-công-cụcông-cụ-kháckhác-nhau&quot;&gt;So Sánh Stream Recorder.io Với Các Công Cụ Khác nhau&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Khi so sánh Stream Recorder.io với các công cụ như Streamlink cũng như OBS Studio, có một nhiều đặc điểm khác nhau cần ghi nhớ. Streamlink chủ yếu một trong những công cụ dòng lệnh, tối ưu cho những người dùng có kinh nghiệm và cần tính hiệu quả cao, nhưng lại khiếm khuyết giao diện dễ sử dụng thân thiện như StreamRecorder.io. Ngược lại, OBS Studio thích hợp hơn cho việc truyền trực tiếp, nhưng lại thường tối ưu hóa cho công việc tải video đã phát. Điều này khiến StreamRecorder.io trở thành một lựa chọn thuận tiện hơn cả cho những ai cần tải xuống video một cách và thuận tiện.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;So với JDownloader cùng Video DownloadHelper, StreamRecorder.io mang đến một trải nghiệm thuận tiện hơn khi là một công cụ dựa trên trình duyệt. Người dùng không cần phải cài đặt phần mềm phức tạp, giúp cho tiết kiệm thời gian và công sức. JDownloader tuy mạnh mẽ song lại khó khăn cho người mới, còn Video DownloadHelper cũng thường hay bị giới hạn do các trang web mà. Đây là lý do Stream Recorder.io nổi bật về tính đơn giản cùng với khả năng tải xuống tải xuống trong nhiều loại stream khác mà không gặp phải đương đầu với rào cản.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Ngoài ra, khi đưa StreamRecorder.io cạnh tranh với các công cụ khác như là YT DLP và bộ tải video 4K, chúng ta cũng nhận thấy điểm mạnh mẽ của Stream Recorder.io về việc cung cấp giao diện trực quan dễ sử dụng và dễ sử dụng. Dù YT DLP là một giải pháp giải pháp mở mạnh mẽ cho tải xuống video từ nhiều nhiều nguồn, song thì cần người dùng có kiến thức kỹ thuật nhất định để tận dụng tối đa công dụng của nó. Bộ tải video 4K có nhiều chức năng nhưng lại đi kèm với chi phí. Với một tất cả những tính năng và dễ dàng, StreamRecorder.io thực sự là một trong một trong những lựa chọn hàng đầu cho người sử dụng vào năm 2025.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;h3 id=&quot;hướng-dẫnhướng-dẫn-chi-tiếthướng-dẫn-sử-dụng-sử-dụng-streamrecorderiocông-cụ-streamrecorderio&quot;&gt;Hướng Dẫn Sử Dụng Sử Dụng công cụ StreamRecorder.io&lt;/h3&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Để bắt đầu sử dụng công cụ này, trước tiên bạn cần đi đến trang web chính của công cụ. Khi bạn vào trang, bạn sẽ thấy giao diện người dùng dễ sử dụng và dễ sử dụng. Không cần tải xuống hay cài đặt ứng dụng, bạn chỉ cần chọn thể loại stream mà bạn muốn ghi lại, chẳng hạn như video từ Nền tảng Twitch hay nền tảng YouTube. Sau đó, hãy dán vào URL video vào khung yêu cầu và nhấn nút để bắt đầu để bắt đầu quá trình ghi lại.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Khi công đoạn ghi lại bắt đầu, StreamRecorder.io sẽ cung cấp thông tin chi tiết tình trạng ghi âm và chất lượng video. Bạn có thể cài đặt một số tùy chọn như định dạng xuất và độ sắc nét video, điều giúp bạn có khả năng dễ dàng lưu trữ video với độ phân giải cao nhất mà không làm giảm chất lượng. Hãy để ý rằng nền tảng này hỗ trợ đa dạng kiểu video khác biệt, giúp bạn linh hoạt trong việc phát hoặc lưu lại video.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;&lt;p&gt;Cuối cùng, khi hoàn tất ghi lại, bạn có thể tải video về máy hoặc lưu trữ trực tuyến, tùy thuộc vào nhu cầu của mình. [https://classroom.miniaturehorsemanship.com/members/cavespace47/activity/213566/ Find top alternatives to StreamRecorder.io] cụ này cũng cho phép bạn quản lý video đã quay lại, tức là việc gỡ bỏ hay bảo quản lâu dài. Đảm bảo bạn kiểm tra những tính năng thêm vào như hỗ trợ phụ đề và lịch trình ghi âm để cải thiện trải nghiệm người dùng.&lt;/p&gt;&lt;br /&gt;&lt;br /&gt;</div></summary> <author><name>Cereallake60</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:HomerDeweese769</id> <title>User:HomerDeweese769</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:HomerDeweese769"/> <updated>2025-06-03T10:21:00Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:HomerDeweese769&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:HomerDeweese769 (page does not exist)"><bdi>HomerDeweese769</bdi></a> was created</p></summary> <author><name>HomerDeweese769</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Marcherlong8648&diff=3298544&oldid=0</id> <title>Marcherlong8648</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Marcherlong8648&diff=3298544&oldid=0"/> <updated>2025-06-03T10:20:58Z</updated> <summary type="html"><p>Created page with &quot;Starting and running home businesses is a terrific way to make income at home. That said, growing your business starts with a good knowledge base. Follow the advice in this ar...&quot;</p><p><b>New page</b></p><div>Starting and running home businesses is a terrific way to make income at home. That said, growing your business starts with a good knowledge base. Follow the advice in this article to establish and maintain your home business.&lt;br /&gt;&lt;br /&gt;Always go out of your way to make your customers happy. Simple things like thank-you notes or freebie items will show your customers that you appreciate their business and generate repeat business. Two things people love are free gifts and appreciation. Prove to them that you appreciate them as customers.&lt;br /&gt;&lt;br /&gt;Join a few online forums and discussion groups that focus on the subject of home business. Search the internet and you will find a lot of great forums that you can become a part of. Blogs are another great resource when it comes to educating yourself about online businesses.&lt;br /&gt;&lt;br /&gt;When you first start out, send a newsletter to family and friends. Give them exclusive coupon codes, free shipping or other discounts that will help to get your business off the ground. Tell people to speak about your business to their friends. Word of mouth can help make your business thrive in a big way.&lt;br /&gt;&lt;br /&gt;Try to find the average market price before you sell something. This clues you in on what customers are willing to pay for your product or service. Research what your competition has and what they charge, and offer your products at a more competitive price. Never talk negatively about your competition, focus on marketing your good qualities.&lt;br /&gt;&lt;br /&gt;Spend time in a business forum on the Internet. Talking to others trying to do the same thing as you can be helpful. You can compare ideas and suggestions with other people who are working from home.&lt;br /&gt;&lt;br /&gt;To better track your business-related spending, open a specific checking account for your business. Make all business-related transactions using this account. You will get a better idea of your progress. It is also a good idea to open a specific credit card for your business.&lt;br /&gt;&lt;br /&gt;Anyone with a flair for the artistic can find work in graphic design. Many places that operate locally enjoy using independent designers because they're more flexible and can also personalize their services. This gives you the advantage over the bigger guy.&lt;br /&gt;&lt;br /&gt;Self-promotion is key to success with a home business, so make sure you are willing to do that. You are going to have to be able to sell your product to a lot of people who may buy from you; that is one of the the jobs of a business owner. Your customers need to feel your products are high quality. Successful self-promotion is critical to earning big profits.&lt;br /&gt;&lt;br /&gt;When you run a business from home, ensuring that you make good use of online marketing and other Internet resources is a great way to build success. There are a variety of Internet marketing tools, including blogs, emails, forums and articles. Actively using these tools can put more money on the books through giving your business more exposure.&lt;br /&gt;&lt;br /&gt;Do [https://tuvanbaohiem.info/bao-viet-tam-binh-la-chan-suc-khoe-vung-vang-cho-ca-gia-dinh-ban/ bao viet tam binh] . Examine the market for your business idea, and make sure it is not already saturated. When the market is already saturated, there is no point in trying to join it. In other words, do your homework first to see if you are picking a business that you can succeed in without a lot of competition.&lt;br /&gt;&lt;br /&gt;When running a home business that is a daycare, depending on how many kids you have, it is important to have sufficient help. If you are lacking sufficient help, everything will be out of control.&lt;br /&gt;&lt;br /&gt;You may be tempted to allow customers some financial slack in the beginning of your relationships with them, however this can pose a potential threat to your profitability. Have a solid payment plan visible on all of your documents and do not waiver from it. It is also a good idea to include a clause for late penalties, within reason, for those who neglect their payment.&lt;br /&gt;&lt;br /&gt;This article mentioned previously that running a business from home can be successful if you understand how to run it and keep the business going. Apply the tips from this article and do more research on home businesses before you get started.</div></summary> <author><name>Marcherlong8648</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Mcfarlandottesen6690</id> <title>User:Mcfarlandottesen6690</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Mcfarlandottesen6690"/> <updated>2025-06-03T10:20:56Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Mcfarlandottesen6690&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Mcfarlandottesen6690 (page does not exist)"><bdi>Mcfarlandottesen6690</bdi></a> was created</p></summary> <author><name>Mcfarlandottesen6690</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Look_at_the_actual_radiopacity_associated_with_restorative_resources_with_some_other_houses_as_well_as_thickness_by_using_a_digital_radiography_method&diff=3298543&oldid=0</id> <title>Look at the actual radiopacity associated with restorative resources with some other houses as well as thickness by using a digital radiography method</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Look_at_the_actual_radiopacity_associated_with_restorative_resources_with_some_other_houses_as_well_as_thickness_by_using_a_digital_radiography_method&diff=3298543&oldid=0"/> <updated>2025-06-03T10:20:47Z</updated> <summary type="html"><p>Created page with &quot;Conclusion Smartphone adaptors for FNL have been established to be of clinical value. Despite being simple devices, they continue to be expensive. This potentially limits acce...&quot;</p><p><b>New page</b></p><div>Conclusion Smartphone adaptors for FNL have been established to be of clinical value. Despite being simple devices, they continue to be expensive. This potentially limits access to junior clinicians, who stand to gain most from the ability to review images of examinations with senior colleagues. Our 3D printed smartphone case provides a cost-effective alternative, with a better fit than generic adaptors, at a print cost of $29 AUD. This is $131 AUD less than the next cheapest commercial alternative. The files are freely available for use and modification. Level of Evidence 4. © 2020 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.Objective Demonstrate the safety and effectiveness of palatal foreshortening and stiffening in reducing snoring severity in nonobstructive sleep apnea (non-OSA) patients complaining of chronic disruptive snoring. Methods In a US-based 8-center, open-label, prospective, single-arm cohort study, 52 consenting adults with chronic disruptive snoring (snoring impacting a patient's life and causing patient or bed partner to seek medical intervention) were treated via office-based placement of resorbable, bidirectional, barbed suture implants into the soft palate under local anesthesia. Prior to intervention, home sleep tests (HSTs) were performed to rule out OSA and to document snoring noise level. Both subject and their bed/sleep partners (also consented) completed questionnaires including bed/sleep partner's scored visual analog scale (VAS) for subjects' snoring severity, and subject scoring for Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI). Following intervention, HSTs, VAS, ESS and PSQI were repeated at 30, 90 and 180 days. Results Mean baseline bed/sleep partner VAS was 7.81 ± 1.59. Mean postimplant VAS scores decreased significantly at each measured interval; to 5.77±2.35 (P less then .001) at 30 days, 4.48 ± 1.81 (P less then .001) at 90 days, and 5.40 ± 2.28 (P less then .001) at 180 days. Post treatment improvements in daytime sleepiness and QOL were also observed. Two partial extrusions were reported. No further adverse events were identified. Conclusion The current study demonstrates the safety and efficacy of the Elevoplasty procedure in reducing snoring severity over a follow-up period of 6 months. Level of Evidence 2b. © 2020 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.Objective Osteoradionecrosis (ORN) of the sphenoid is a rare but potentially lethal complication that can occur after irradiation of nasopharyngeal and clival malignancies. The objective of this study was to describe a multimodal treatment strategy tailored to the clinical signs and to the radiological extent of the disease, and to report on its preliminary results. [https://www.selleckchem.com/products/marimastat.html Proteases inhibitor] Methods Retrospective monocentric study at a tertiary skull base center. Patients treated for a sphenoid ORN from January 2014 to August 2018 were identified and charts were retrospectively reviewed for demographics, histologic tumor type, previous treatments of the tumor, clinical signs at presentation, radiological data, treatment, and outcomes. Sphenoid ORN was treated by a combination of medical therapy, endovascular treatment, and/or surgery. The use of each of these therapeutic modalities was based on the extent of ORN and on the presenting signs. Results Seven patients were included four patients underwent endovascular treatment with occlusion of the internal carotid artery, five patients underwent surgical debridement, and covering of the exposed bone by a local flap, seven patients received antibiotics (in combination with pentoxyphilline, tocopherol, and clodronate in one case). Three patients died after progression of the ORN. The global survival rate was 57% (4/7) with a mean follow-up of 24 months. In one case, ORN was treated successfully by medical treatment only, with a combination of antibiotics, pentoxyphilline, tocopherol, and clodronate. Conclusion This retrospective study describes the results of a management strategy adapted to the extent of the disease in sphenoid ORN and based on medical therapy only, or on a combination of medical therapy, interventional radiology, and/or surgery. Level of evidence 4. © 2020 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.Objective To estimate the prevalence and significance of cranial nerve (CN) imaging abnormalities in patients with hereditary neuropathy and discuss clinical implications. Methods We retrospectively analyzed data from patients at four tertiary academic medical centers with hereditary neuropathy diagnoses who had undergone gadolinium-enhanced magnetic resonance imaging (MRI) of the brain or skull base between 2004 and 2018. MRI scans, as well as computed tomography imaging when available, were reviewed and bivariable analysis was performed to identify predictors of CN abnormalities on imaging. Results Among 39 patients meeting study criteria, 11 had clinical CN deficits (28%) and 8 had CN abnormalities on imaging (21%). Of the patients with CN abnormalities on imaging, half had CN deficits (4/8) and only a quarter had imaging abnormalities of the CNs with the deficits (2/8). Imaging abnormalities were found in varied CNs, including CNs III, V, VII, and the VII/VIII complex in the internal auditory canal. MRI obtained for the purpose of evaluating CN deficits had a statistically significant increased likelihood of containing CN imaging abnormalities. However, CN deficits themselves were not predictive of imaging abnormalities. Conclusion Thickening and enhancement of CNs on MRI may be found in approximately 1/5 of patients with hereditary neuropathies and are inconsistently associated with clinical deficits. These imaging findings should not be mistaken for neoplastic and infectious processes as they may be manifestations of the patients' underlying genetic neuropathy. Level of Evidence 4. © 2020 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.</div></summary> <author><name>Jawhen43</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Turn_over_within_a_corporate_and_business_merger_Exactly_how_place_of_work_community_modify_influences_staying&diff=3298542&oldid=0</id> <title>Turn over within a corporate and business merger Exactly how place of work community modify influences staying</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Turn_over_within_a_corporate_and_business_merger_Exactly_how_place_of_work_community_modify_influences_staying&diff=3298542&oldid=0"/> <updated>2025-06-03T10:20:46Z</updated> <summary type="html"><p>Created page with &quot;We found that the presence of four parallel pathways leads to a 2.5-fold acceleration in folding; that is, the effective folding rate from the unfolded to folded ensembles is...&quot;</p><p><b>New page</b></p><div>We found that the presence of four parallel pathways leads to a 2.5-fold acceleration in folding; that is, the effective folding rate from the unfolded to folded ensembles is 2.5 times as large as the rate constant for the fastest individual pathway. Since many G4 sequences can adopt many more than four isomers, folding accelerations of more than an order of magnitude are possible via this mechanism.&lt;br /&gt;&lt;br /&gt; Historically, symptomatic, benign intradural extramedullary (IDEM) spine tumors have been managed with surgical resection. However, minimal robust data regarding patient-reported outcomes (PROs) following treatment of symptomatic lesions exists. Moreover, there are increasing reports of radiosurgical management of these lesions without robust health-related quality of life data.&lt;br /&gt;&lt;br /&gt; To prospectively analyze PROs among patients with benign IDEM spine tumors undergoing surgical resection to define the symptomatic efficacy of surgery.&lt;br /&gt;&lt;br /&gt; Prospective, single-center observational cohort study of patients with benign IDEM spine tumors undergoing open surgical resection. Pre- and postoperative Brief Pain Index (BPI) and MD Anderson Symptom Inventory (MDASI) questionnaires were used to quantitatively assess their symptom control after surgical intervention. Matched pairs were analyzed with the Wilcoxon signed-rank test.&lt;br /&gt;&lt;br /&gt; A total of 57 patients met inclusion criteria with both pre- and postoperative PROs. There were 35 schwannomas, 18 meningiomas, 2 neurofibromas, 1 paraganglioma, and 1 mixed schwannoma/neurofibroma. Most patients were American Spinal Injury Association Impairment (ASIA) E (93%) with high-grade spinal cord compression (77%), and underwent either a 2 or 3 level laminectomy (84%). Surgical resection resulted in statistically significant improvement in all 3 composite BPI constructs of pain-severity, pain-interference, and overall patient pain experience (P&amp;lt;.0001). Surgical resection resulted in statistically significant improvements in all composite scores for the MDASI core symptom severity, spine tumor, and disease interference constructs (P&amp;lt;.01). Three patients (5%) had postoperative complications requiring surgical interventions (2 wound revisions and 1 ventriculo-peritoneal shunt).&lt;br /&gt;&lt;br /&gt; Surgical resection of IDEM spine tumors provides rapid, significant, and durable improvement in PROs.&lt;br /&gt;&lt;br /&gt;Surgical resection of IDEM spine tumors provides rapid, significant, and durable improvement in PROs.&lt;br /&gt;&lt;br /&gt; Intracranial atherosclerotic disease (ICAD) is one of the leading causes of stroke worldwide. Patients with ICAD who initially present with ischemia in border-zone areas and undergo intensive medical management (IMM) have the highest recurrence rates (37% at 1 yr) because of association with hemodynamic failure and poor collaterals.&lt;br /&gt;&lt;br /&gt; To evaluate the effect of encephaloduroarteriosynagiosis (EDAS) on stroke recurrence in patients with ICAD and border-zone stroke (BDZS) at presentation.&lt;br /&gt;&lt;br /&gt; A phase II clinical trial of EDAS revascularization for symptomatic ICAD failing medical management (EDAS Revascularization for Symptomatic Intracranial Atherosclerosis Steno-occlusive [ERSIAS]) was recently concluded. We analyze the outcomes of the subgroup of patients with BDZS at presentation treated with EDAS vs the previously reported Stenting versus Aggressive Medical Management for Preventing Recurrent stroke in Intracranial Stenosis (SAMMPRIS) IMM subgroup with BDZS at presentation.&lt;br /&gt;&lt;br /&gt; Of 52 patients included in the ERSIAS trial, 35 presented with strokes at baseline, and 28 had a BDZ pattern, including 15 (54%) with exclusive BDZS and 13 (46%) with mixed patterns (BDZ plus other distribution). Three of the 28 (10.7%) had recurrent strokes up to a median follow-up of 24 months. The rate of recurrent stroke in ICAD patients with BDZS at presentation after EDAS was significantly lower than the rate reported in the SAMMPRIS IMM subgroup with BDZS at presentation (10.7%vs 37% P=.004, 95% CI=0.037-0.27).&lt;br /&gt;&lt;br /&gt; ICAD patients with BDZS at presentation have lower rates of recurrent stroke after EDAS surgery than those reported with medical management in the SAMMPRIS trial. These results support further investigation of EDAS in a randomized clinical trial.&lt;br /&gt;&lt;br /&gt;ICAD patients with BDZS at presentation have lower rates of recurrent stroke after EDAS surgery than those reported with medical management in the SAMMPRIS trial. These results support further investigation of EDAS in a randomized clinical trial.&lt;br /&gt;&lt;br /&gt; Aneurysmal subarachnoid hemorrhage (aSAH) is associated with a high mortality and poor neurologic outcomes. The biologic underpinnings of the morbidity and mortality associated with aSAH remain poorly understood.&lt;br /&gt;&lt;br /&gt; To ascertain potential insights into pathological mechanisms of injury after aSAH using an approach of metabolomics coupled with machine learning methods.&lt;br /&gt;&lt;br /&gt; Using cerebrospinal fluid (CSF)samples from 81 aSAH enrolled in a retrospective cohort biorepository, samplescollected during the peak of delayed cerebral ischemiawere analyzed using liquid chromatography-tandem mass spectrometry. A total of 138 metabolites were measured and quantified in each sample. Data were analyzed using elastic net (EN) machine learning and orthogonal partial least squares-discriminant analysis (OPLS-DA) to identify the leading CSF metabolites associated with poor outcome, as determined by the modified Rankin Scale (mRS) at discharge and at 90 d. Repeated measures analysis determined the effect size for each metabolite on poor outcome.&lt;br /&gt;&lt;br /&gt; EN machine learning and OPLS-DA analysis identified 8 and 10 metabolites, respectively, that predicted poor mRS (mRS 3-6) at discharge and at 90 d. Of these candidates, symmetric dimethylarginine (SDMA), dimethylguanidine valeric acid (DMGV), and ornithine were consistent markers, with an association with poor mRS at discharge (P=.0005, .002, and .0001, respectively) and at 90 d (P=.0036, .0001, and .004, respectively). SDMA also demonstrated a significantly elevated CSF concentration compared with nonaneurysmal subarachnoid hemorrhage controls (P=.0087).&lt;br /&gt;&lt;br /&gt; SDMA, DMGV, and ornithine are vasoactive molecules linked to the nitric oxide pathway that predicts poor outcome after severe aSAH. [https://www.selleckchem.com/products/cx-5461.html CX-5461] Further study of dimethylarginine metabolites in brain injury after aSAH is warranted.&lt;br /&gt;&lt;br /&gt;SDMA, DMGV, and ornithine are vasoactive molecules linked to the nitric oxide pathway that predicts poor outcome after severe aSAH. Further study of dimethylarginine metabolites in brain injury after aSAH is warranted.</div></summary> <author><name>Topbun2</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Bentsenhoppe3271</id> <title>User:Bentsenhoppe3271</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Bentsenhoppe3271"/> <updated>2025-06-03T10:20:39Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Bentsenhoppe3271&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Bentsenhoppe3271 (page does not exist)"><bdi>Bentsenhoppe3271</bdi></a> was created</p></summary> <author><name>Bentsenhoppe3271</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Hougaardladegaard9224</id> <title>User:Hougaardladegaard9224</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Hougaardladegaard9224"/> <updated>2025-06-03T10:20:32Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Hougaardladegaard9224&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Hougaardladegaard9224 (page does not exist)"><bdi>Hougaardladegaard9224</bdi></a> was created</p></summary> <author><name>Hougaardladegaard9224</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=The_outcome_regarding_regimen_postanesthesia_care_product_extubation_pertaining_to_pediatric_operative_patients_on_safety_and_operating_place_effectiveness&diff=3298541&oldid=0</id> <title>The outcome regarding regimen postanesthesia care product extubation pertaining to pediatric operative patients on safety and operating place effectiveness</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=The_outcome_regarding_regimen_postanesthesia_care_product_extubation_pertaining_to_pediatric_operative_patients_on_safety_and_operating_place_effectiveness&diff=3298541&oldid=0"/> <updated>2025-06-03T10:20:32Z</updated> <summary type="html"><p>Created page with &quot;Eighteen weeks after discharge, the infant is still on vitamin K supplementation. She did not have any further bleedings and no neurologic or developmental impairment.&lt;br /&gt;&lt;b...&quot;</p><p><b>New page</b></p><div>Eighteen weeks after discharge, the infant is still on vitamin K supplementation. She did not have any further bleedings and no neurologic or developmental impairment.&lt;br /&gt;&lt;br /&gt; Alpha-1-antitrypsin deficiency can lead to vitamin K deficiency in young infants even with adequate prophylaxis. Spontaneous haemorrhagic pericardial effusion was a new manifestation of vitamin K deficiency bleeding in our patient and should be considered and ruled out in young infants who present with acute anaemia and poor clinical condition.&lt;br /&gt;&lt;br /&gt;Alpha-1-antitrypsin deficiency can lead to vitamin K deficiency in young infants even with adequate prophylaxis. Spontaneous haemorrhagic pericardial effusion was a new manifestation of vitamin K deficiency bleeding in our patient and should be considered and ruled out in young infants who present with acute anaemia and poor clinical condition.&lt;br /&gt;&lt;br /&gt; Studies about the incidence and severity of coronavirus disease 2019 (COVID-19) in children are still significantly lower than those in adults. Moreover, data on the effect of COVID-19 in children with congenital heart disease (CHD) are limited. To the best of our knowledge, this study first reported mortality in a child with CHD who acquired COVID-19.&lt;br /&gt;&lt;br /&gt; A 16-month-old boy presented to the emergency department due to shortness of breath, fever, cough, and poor oral intake. [https://www.selleckchem.com/products/bip-inducer-x-bix.html selleck inhibitor] He tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). He required mechanical ventilation for rapidly progressing respiratory failure. The patient had a large mid-muscular ventricular septal defect (VSD) that was closed percutaneously at the age of 13 months. Moreover, we followed his hospital sequelae from admission to death.&lt;br /&gt;&lt;br /&gt; This child had multiple risk factors, including malnutrition and persistent pulmonary hypertension (PH) after late closure of the VSD. The pre-existing PH could have been aggravated bcorroborate multisystem inflammatory syndrome in children, which was described recently among paediatric patients with COVID-19.&lt;br /&gt;&lt;br /&gt; Malignant primary cardiac neoplasms are rare and primary cardiac angiosarcoma is the most common and aggressive subtype. It most commonly presents in middle-aged males and due to its non-specific clinical presentation, the diagnosis is often delayed until advanced disease is already present. Clinical presentation is determined by manifestations of local infiltration or metastatic disease and making an early diagnosis is extremely challenging.&lt;br /&gt;&lt;br /&gt; A 15-year-old previously healthy boy was admitted to the emergency department with a history of pathological weight loss and functional decline. The patient was found to have a left-sided pneumothorax as well as bilateral diffusely spread pulmonary nodules on plain chest radiograph. Computed tomography chest confirmed widespread pulmonary metastases and a right atrial filling defect. Echocardiography revealed a right atrial tumour and transvenous endomyocardial biopsy of the tumour was done under fluoroscopic and echocardiographic guidance. A diagnosis of primary carthesia.&lt;br /&gt;&lt;br /&gt; Transcatheter aortic valve implantation (TAVI) has become a first-line therapeutic option in patients with severe, symptomatic aortic stenosis at increased surgical risk. Despite its success, the TAVI procedure has been associated with acute life-threatening complications as myocardial infarction secondary to periprocedural coronary occlusion, annular rupture, or vascular injury.&lt;br /&gt;&lt;br /&gt; A 79-year-old woman with a dysfunctional bioprosthetic valve following previous surgical valve replacement was hospitalized in our institution to perform a Valve-in-Valve Transcatheter Aortic Valve Replacement (ViV TAVR). Shortly after the implantation of an Evolut R valve (without complication), left ventricle dysfunction with apical akinesia and basal hyperkinesia was identified during bedside transthoracic echocardiography, in spite of a good prosthesis implantation and function. A concomitant Troponin elevation was noted, and the day-after resting electrocardiogram showed a lateral T-wave inversion. Coronary computed tomograppathological explanation can be formulated.&lt;br /&gt;&lt;br /&gt; Management of heavily calcified coronary arteries is still a major challenge in interventional cardiology. Inadequate stent expansion in calcific lesions is the single most important predictor of stent thrombosis and in-stent restenosis. Rotational atherectomy (RA) is an important tool to modify the calcium burden but is associated with limitations and requires specific skills. Intravascular lithotripsy (IVL) is a novel technique to treat calcified stenotic lesions and has been proposed as an alternative to RA with promising results.&lt;br /&gt;&lt;br /&gt; We report a case of a patient with severely calcified right coronary artery stenosis successfully treated with combination of RA and IVL.&lt;br /&gt;&lt;br /&gt; In this case, we demonstrate that the RA and IVL are complementary strategies, not sufficient on their own and not alternative to each other.&lt;br /&gt;&lt;br /&gt;In this case, we demonstrate that the RA and IVL are complementary strategies, not sufficient on their own and not alternative to each other.&lt;br /&gt;&lt;br /&gt; Left ventricular outflow tract (LVOT) obstruction is an important determinant of the management of hypertrophic cardiomyopathy (HCM). With a nationwide shortage of amyl nitrite in 2019, we implemented a 'repetitive squat-to-stand' manoeuvre to provoke LVOT obstruction during echocardiography.&lt;br /&gt;&lt;br /&gt; A 64-year-old female was referred with symptomatic HCM refractory to pharmacologic therapy. Transthoracic echocardiography showed minor LVOT obstruction with conventional imaging at rest and during Valsalva manoeuvre, but severe obstruction was confirmed with the repetitive squat-to-stand manoeuvre. Alcohol septal ablation via the first septal perforator was performed with subsequent resolution of symptoms.&lt;br /&gt;&lt;br /&gt; Due to the dynamic nature of LVOT obstruction, a series of provocative manoeuvres including Valsalva manoeuvre, inhalation of amyl nitrite, and exercise are often necessary to maximally augment ventricular obstruction. The recent unavailability of amyl nitrite during a nationwide shortage prompted the implementang position decreases preload and afterload, both of which augment dynamic LVOT obstruction. Repetition of squatting and standing appears to enhance the sensitivity of the manoeuvre, particularly when exertional symptoms are reproduced. In this case, repetitive squat-to-stand manoeuvre led to the identification of severe LVOT obstruction which may not have been diagnosed otherwise, alteration of treatment to septal reduction therapy, and subsequent resolution of symptoms.</div></summary> <author><name>Trailway0</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Entirely_Computerized_Three_dimensional_Heart_failure_MRI_Localisation_along_with_Division_Making_use_of_Serious_Neural_Networks&diff=3298540&oldid=0</id> <title>Entirely Computerized Three dimensional Heart failure MRI Localisation along with Division Making use of Serious Neural Networks</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Entirely_Computerized_Three_dimensional_Heart_failure_MRI_Localisation_along_with_Division_Making_use_of_Serious_Neural_Networks&diff=3298540&oldid=0"/> <updated>2025-06-03T10:20:30Z</updated> <summary type="html"><p>Created page with &quot;Revision arthroplasty involving mega-implants is associated with a high complication rate. In particular, infection is a serious complication of revision arthroplasty of hip a...&quot;</p><p><b>New page</b></p><div>Revision arthroplasty involving mega-implants is associated with a high complication rate. In particular, infection is a serious complication of revision arthroplasty of hip and knee joints and has been reported to have an average rate of 18%, and for mega-implants, the range is from 3 to 36%. This study was designed to analyze the strategy of treatment of infection of mega-endoprostheses of the lower extremities in our patient cohort, particularly the management of chronic infection.&lt;br /&gt;&lt;br /&gt; This was a retrospective study that focused on the results of the treatment of periprosthetic infections of mega-implants of the lower extremities. We identified 26 cases with periprosthetic infections out of 212 patients with 220 modular mega-endoprostheses of the lower extremities who were treated in our department between September 2013 and September 2019. As a reinfection or recurrence, we defined clinical and microbiological recurrences of local periprosthetic joint infections after an antibiotic-free period.&lt;br /&gt;&lt;br /&gt; In this therapy are the most important therapeutic tools in all cases of periprosthetic infections, regardless of the time of onset. Further studies are needed to standardize management strategies of such infections. Nevertheless, it is not uncommon for compromises to be made based on the particular condition of the individual.Women with early menopause or primary ovarian insufficiency (POI) experience a menopausal state a decade or more earlier than their peers. The health consequences for POI are vast and varied with detrimental effects seen on neurological, psychological, bone, and cardiovascular systems. The risk profile of POI patients requires special attention, as they differ from a typical menopausal population. This review will explore the health risks associated with POI and examine the various treatment options and also the risks associated with hormone therapy. Given the risks and benefits, POI patients should be strongly encouraged to start hormone therapy until the median age of menopause.&lt;br /&gt;&lt;br /&gt; High estradiol (E&lt;br /&gt;&lt;br /&gt; ) levels are linked to an increased risk of venous thromboembolism; however, the underlying molecular mechanism(s) remain poorly understood. We previously identified an E&lt;br /&gt;&lt;br /&gt; -responsive microRNA (miR), miR-494-3p, that downregulates protein S expression, and posited additional coagulation factors, such as tissue factor, may be regulated in a similar manner via miRs.&lt;br /&gt;&lt;br /&gt; To evaluate the coagulation capacity of cohorts with high physiological E&lt;br /&gt;&lt;br /&gt; , and to further characterize novel E&lt;br /&gt;&lt;br /&gt; -responsive miR and miR regulation on tissue factor in E&lt;br /&gt;&lt;br /&gt; -related hypercoagulability.&lt;br /&gt;&lt;br /&gt; Ceveron Alpha thrombin generation assay (TGA) was used to assess plasma coagulation profile of three cohorts. The effect of physiological levels of E&lt;br /&gt;&lt;br /&gt; , 10 nM, on miR expression in HuH-7 cells was compared using NanoString nCounter and validated with independent assays. The effect of tissue factor-interacting miR was confirmed by dual-luciferase reporter assays, immunoblotting, flow cytometry, biochemistry assays, and TGA.&lt;br /&gt;&lt;br /&gt; Plasma samples from pregnant women and women on the contraceptive pill were confirmed to be hypercoagulable (compared with sex-matched controls). At equivalent and high physiological levels of E&lt;br /&gt;&lt;br /&gt; , miR-365a-3p displayed concordant E&lt;br /&gt;&lt;br /&gt; downregulation in two independent miR quantification platforms, and tissue factor protein was upregulated by E&lt;br /&gt;&lt;br /&gt; treatment. Direct interaction between miR-365a-3p and &lt;br /&gt;&lt;br /&gt; 3'UTR was confirmed and overexpression of miR-365a-3p led to a decrease of (1) tissue factor mRNA transcripts, (2) protein levels, (3) activity, and (4) tissue factor-initiated thrombin generation.&lt;br /&gt;&lt;br /&gt; miR-365a-3p is a novel tissue factor regulator. High E&lt;br /&gt;&lt;br /&gt; concentrations induce a hypercoagulable state via a miR network specific for coagulation factors.&lt;br /&gt;&lt;br /&gt; miR-365a-3p is a novel tissue factor regulator. High E2 concentrations induce a hypercoagulable state via a miR network specific for coagulation factors.A CSF leak is a common complication in spine surgery which is usually closed effectivly by suture and/or epidural patches. [https://www.selleckchem.com/products/jsh-150.html selleck kinase inhibitor] There is currently no algorithm to treat a recurrent CSF leak that fails to be closed initially. We describe the case of a recurrent cerebrospinal fluid leak that we have successfully treated using an inlay-onlay dural repair technique.&lt;br /&gt;&lt;br /&gt; We evaluate the feasibility and potential advantages of spinal CT navigation in the placement of pedicle screws at the cervicothoracic junction in the sitting position to counteract the anatomy-related limitations of 2D fluoroscopy.&lt;br /&gt;&lt;br /&gt; We retrospectively analyze the data from 15 patients who underwent CT-based navigation-guided placement of a total of 36 pedicle screws at the cervicothoracic junction in the sitting position.&lt;br /&gt;&lt;br /&gt; CT-based spinal navigation is a useful method in increasing accuracy of pedicle screw instrumentation in the sitting position, successfully counteracting the anatomy-related limitations of 2D fluoroscopy at the cervicothoracic junction.&lt;br /&gt;&lt;br /&gt; CT-based navigation-guided placement of pedicle screws at the cervicothoracic junction in the sitting position proved to be an accurate, safe, and user-friendly method.&lt;br /&gt;&lt;br /&gt; CT-based navigation-guided placement of pedicle screws at the cervicothoracic junction in the sitting position proved to be an accurate, safe, and user-friendly method.&lt;br /&gt;&lt;br /&gt; Spinal fusion for symptomatic lumbar spondylolisthesis can be accomplished using an open or minimally invasive surgical (MIS) technique. Evaluation of segmental spondylolisthesis and instabilities and review of their therapies are inseparably connected with lumbar tomographic imaging. We analyzed a cohort of patients who underwent MIS or open monosegmental dorsal fusion and compared surgical outcomes along with complication rates. We furthermore evaluated the influence of virtual reality (VR) visualization on surgical planning in lumbar fusion.&lt;br /&gt;&lt;br /&gt; Patient files were retrospectively analyzed regarding patient- and disease-related data, operative performance, surgical outcomes, and perioperative surgical complications. Preoperative computed tomography (CT) and magnetic resonance imaging (MRI) scans were retrospectively visualized via VR software. A questionnaire evaluated the influence of three-dimensional (3D) VR images versus two-dimensional CT and MRI scans on therapy planning, fusion method, and surgical technique and procedure.</div></summary> <author><name>Jumpperson1</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Effects_of_cricothyroid_as_well_as_thyroarytenoid_conversation_in_words_management_Muscles_exercise_singing_collapse_function_circulation_and_acoustics&diff=3298539&oldid=0</id> <title>Effects of cricothyroid as well as thyroarytenoid conversation in words management Muscles exercise singing collapse function circulation and acoustics</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Effects_of_cricothyroid_as_well_as_thyroarytenoid_conversation_in_words_management_Muscles_exercise_singing_collapse_function_circulation_and_acoustics&diff=3298539&oldid=0"/> <updated>2025-06-03T10:20:24Z</updated> <summary type="html"><p>Created page with &quot;The diagnosis of healthcare-associated ventriculitis and meningitis (HAVM) is challenging in the ICU setting. Traditional cerebrospinal fluid (CSF) markers and clinical signs...&quot;</p><p><b>New page</b></p><div>The diagnosis of healthcare-associated ventriculitis and meningitis (HAVM) is challenging in the ICU setting. Traditional cerebrospinal fluid (CSF) markers and clinical signs of infection fail to diagnose HAVM in the critically ill setting. We sought to determine the diagnostic accuracy of measuring levels of high-mobility group box 1 (HMGB1) protein in cerebrospinal fluid (CSF) for the diagnosis of HAVM.&lt;br /&gt;&lt;br /&gt; In this prospective observational cohort study, we enrolled 29 patients with an implanted external ventricular drainage (EVD). We tested the accuracy of CSF-HMGB1 as a diagnostic test for HAVM when compared to standard CSF parameters.&lt;br /&gt;&lt;br /&gt; HAVM was diagnosed in 11/29 (37.9%) patients. These patients had significantly higher CSF-HMGB1 levels compared to patients without HAVM (median [IQR] 43.39 [83.51] ng/mL vs 6.46 ng/mL [10.94]; P&amp;lt;0.001). CSF-HMGB1 and CSF-glucose were independently related to HAVM, with OR's (95% CI) of 15.43 (15.37 to 15.48, P&amp;lt;0.0001) and 0.31 (0.30 to 0.32, P&amp;lt;0.0001), respectively. The AUC [CI] of CSF-HMGB1 to predict HAVM was 0.83 [0.72 to 0.94].&lt;br /&gt;&lt;br /&gt; HMGB1 is an accurate marker of HAVM and it adds incremental diagnostic value when paired with CSF-glucose measurements. Future larger and multicenter studies should assess the incremental diagnostic value of HMGB1 data when used alongside other established CSF markers of infection, and the external validity of these preliminary results.&lt;br /&gt;&lt;br /&gt;HMGB1 is an accurate marker of HAVM and it adds incremental diagnostic value when paired with CSF-glucose measurements. Future larger and multicenter studies should assess the incremental diagnostic value of HMGB1 data when used alongside other established CSF markers of infection, and the external validity of these preliminary results.&lt;br /&gt;&lt;br /&gt; Being in an unfamiliar environment away from family can exacerbate emotional stress in hospitalised older people with dementia. Technology solutions can be used to address their mental and emotional health needs.&lt;br /&gt;&lt;br /&gt; To generate greater understanding of technology adoption and to test strategies supporting virtual care interventions in hospitalised older people with dementia, such as the use of an iPad to connect them with their family members.&lt;br /&gt;&lt;br /&gt; Older people with dementia in two Canadian hospitals were observed and interviewed to explore their experiences of using an iPad. Focus groups were conducted with staff and interviews were undertaken with two frontline nurses and three research partners with lived experience of dementia in hospitalised older people. Data were thematically analysed in collaboration with 12 stakeholders. Strategies to overcome the barriers identified were tested as part of the study.&lt;br /&gt;&lt;br /&gt; There were three main barriers to implementing virtual care interventions lack of familiarity with the technology; difficulties with operating the device; and privacy and connectivity issues. Strategies to overcome these barriers included providing personalised support, working with users to support adaptation, and ensuring privacy and optimal connectivity.&lt;br /&gt;&lt;br /&gt; Using an iPad has the potential to enable hospitalised older people with dementia to connect with their family members and take part in activities that support person-centred care. This is particularly important in times, such as the COVID-19 pandemic, when restrictions to hospital visits lead to social isolation.&lt;br /&gt;&lt;br /&gt;Using an iPad has the potential to enable hospitalised older people with dementia to connect with their family members and take part in activities that support person-centred care. This is particularly important in times, such as the COVID-19 pandemic, when restrictions to hospital visits lead to social isolation.Cancer cells are abnormal cells that can reproduce and regenerate rapidly. They are characterized by unlimited proliferation, transformation and migration, and can destroy normal cells. [https://www.selleckchem.com/products/d-luciferin.html D-Luciferin ic50] To meet the needs for cell proliferation and migration, tumor cells acquire molecular materials and energy through unusual metabolic pathways as their metabolism is more vigorous than that of normal cells. Multiple carcinogenic signaling pathways eventually converge to regulate three major metabolic pathways in tumor cells, including glucose, lipid, and amino acid metabolism. The distinct metabolic signatures of cancer cells reflect that metabolic changes are indispensable for the genesis and development of tumor cells. In this review, we report the unique metabolic alterations in tumor cells which occur through various signaling axes, and present various modalities available for cancer diagnosis and clinical therapy. We further provide suggestions for the development of anti-tumor therapeutic drugs.Congenital heart diseases are one of the most common multi-factorial fetal abnormalities caused by a complex of endo- and exogenous factors. It is known that mutations in xenobiotic biotransformation genes can be associated with the pathogenesis of congenital heart diseases. In the presented research, 131 children with congenital heart diseases and 101 women having children with this pathology were included in the study group. In control group, 103 healthy children and their mothers were included. Single-nucleotide polymorphisms in the xenobiotic biotransformation genes CYP1A1 (rs1048943), CYP1A2 (rs762551), GSTP1 (rs6591256, rs1871042 and rs17593068) were detected by the real-time polymerase chain reaction. Gene-gene interactions were determined using the Multifactor Dimensionality Reduction method. We obtained no difference in the frequency of CYP1A1, CYP1A2 and GSTP1 between the study and control groups. At the same time, the genetic combinations GSTP1 (rs6591256)-GSTP1 (rs1871042) and GSTP1 (rs6591256)-GSTP1 (rs1871042)-CYP1A1 (rs1048943) in women; and GSTP1 (rs1793068)-GSTP1 (rs6591256)-GSTP1 (rs1871042)-CYP1A1 (rs1048943)-CYP1A2 (rs762551) in children contribute to the pathogenesis of congenital heart diseases.&lt;br /&gt;&lt;br /&gt; Up to 1 in 5 infants in the United States are exposed to alcohol prenatally, resulting in neurodevelopmental deficits categorized as fetal alcohol spectrum disorders (FASD). Choline supplementation ameliorates some deficits, suggesting that alcohol exposure (AE) perturbs cholinergic neurotransmission and development. Behavioral interventions, which upregulate cholinergic neurotransmission, rescue cognitive deficits in rodent models of FASD.&lt;br /&gt;&lt;br /&gt; We investigated the impacts of two interventions (either wheel-running (WR) or &quot;super intervention,&quot; WR plus exposure to a complex environment) on cholinergic neuronal morphology in the nucleus basalis of Meynert (NBM), the source of cortical cholinergic input, and prefrontal cortex (PFC) in a rodent model of FASD. One third of the total 47 male pups received intragastric intubation of ethanol in milk substitute during postnatal days (PD) 4-9. Another third served as sham-intubated procedural controls while the final third served as suckle controls. Rats from each group were exposed to either intervention during PD 30-72.</div></summary> <author><name>Dinghyyarn2</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Specific_climatic_conditions_and_human_freedom_has_an_effect_on_on_the_SARSCoV2_break_out_in_Colombia_Application_of_an_artificial_nerve_organs_community_strategy&diff=3298538&oldid=0</id> <title>Specific climatic conditions and human freedom has an effect on on the SARSCoV2 break out in Colombia Application of an artificial nerve organs community strategy</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Specific_climatic_conditions_and_human_freedom_has_an_effect_on_on_the_SARSCoV2_break_out_in_Colombia_Application_of_an_artificial_nerve_organs_community_strategy&diff=3298538&oldid=0"/> <updated>2025-06-03T10:20:23Z</updated> <summary type="html"><p>Created page with &quot;Inappropriate posture in children while playing some string instruments can cause back pain and alterations of the spine. To date, there is no research on the effect of exerci...&quot;</p><p><b>New page</b></p><div>Inappropriate posture in children while playing some string instruments can cause back pain and alterations of the spine. To date, there is no research on the effect of exercise on children who play a musical instrument, although it is known that transversus abdominis muscle control through the Pilates method has shown pain reduction and posture improvement in this population.&lt;br /&gt;&lt;br /&gt; To assess the effectiveness of the Pilates method combined with therapeutic exercise with respect to therapeutic exercise exclusively in reducing pain and improving postural alignment in children playing string instruments applying a protocol of low dose to increase children's adherence to training.&lt;br /&gt;&lt;br /&gt; A randomized controlled pilot study was designed with two parallel intervention groups. Twenty-five children (10-14 years old) were randomized in two intervention groups Pilates method with therapeutic exercise (experimental) and therapeutic exercise (control) for 4 weeks (50 min per day, one day per week). Two assessments were performed (before and after treatment) to assess back pain and shoulders and hips alignment using a visual analog scale and the Kinovea program.&lt;br /&gt;&lt;br /&gt; Statistically significant differences were obtained for pain reduction before (&lt;br /&gt;&lt;br /&gt; = 0.04) and after (&lt;br /&gt;&lt;br /&gt; = 0.01) playing the instrument in the experimental group. There were no significant changes in alignment improvement in any of the two groups.&lt;br /&gt;&lt;br /&gt; The application of a low dose of the Pilates method combined with therapeutic exercise could be a beneficial intervention for pain reduction before and after musical practice in children who play string instruments.&lt;br /&gt;&lt;br /&gt;The application of a low dose of the Pilates method combined with therapeutic exercise could be a beneficial intervention for pain reduction before and after musical practice in children who play string instruments.The scalable delivery of genomic medicine requires collaboration between genetics and non-genetics providers. Thus, it is essential to investigate and address the perceived value of and barriers to incorporating genetic testing into the clinical practice of primary care providers (PCPs). We used a mixed-methods approach of qualitative interviews and surveys to explore the experience of PCPs involved in the pilot DNA-10K population genetic testing program. Similar to previous research, PCPs reported low confidence with tasks related to ordering, interpreting and managing the results of genetic tests, and identified the need for additional education. PCPs endorsed high levels of utility for patients and their families but noted logistical challenges to incorporating genetic testing into their practice. Overall PCPs were not familiar with the United States' Genetic Information Nondiscrimination Act and they expressed high levels of concern for patient data privacy and potential insurance discrimination. This PCP feedback led to the development and implementation of several processes to improve the PCP experience with the DNA-10K program. These results contribute to the knowledge base regarding genomic implementation using a mixed provider model and may be beneficial for institutions developing similar clinical programs.Background. Public markets were exempted from the restrictive regulations instituted to limit the rapid spread of the COVID-19 pandemic in the Democratic Republic of the Congo (DRC). In the early stage of the pandemic, we assessed people's knowledge, attitudes, and behavior on public markets towards COVID-19. Methods. We conducted a cross-sectional study from 16 to 29 April 2020 among sellers and customers frequenting the food sections of ten public markets in three large cities (Kolwezi, Likasi, and Lubumbashi) and one small town (Lwambo) of the former Katanga province. We administered a questionnaire on knowledge (about clinical characteristics, transmission and prevention) and on attitudes in relation to COVID-19. We also observed prevailing practices (hand-washing and mask-wearing). [https://www.selleckchem.com/products/xl092.html find more] Results Of the 347 included participants (83% women, 83% sellers), most had low socioeconomic status and a low level of education. Only 30% of participants had correct knowledge of COVID-19. The majority of the respondents (88%) showed no confidence in the government's ability to manage the upcoming pandemic crisis. Nearly all respondents (98%) were concerned about the associated increase in food insecurity. Preventive practices were rarely in place. Conclusion For an effective implementation of measures to prevent the spread of COVID-19 in Africa, appropriate health education programs to improve knowledge and attitudes are warranted among the population frequenting public markets.The polyphenolic composition and antioxidant activity of grape seeds, as byproducts of red winemaking, depend on various factors, such as grape cultivar, vintage effect, grape maturity and winemaking methods. In the present work, the influence of the maceration length on the polyphenolic and antioxidant characteristics of the seeds of four Italian red grape cultivars ('Barbera', 'Grignolino', 'Nebbiolo', and 'Uvalino'), sampled from the fermentation tanks after short (two days) and medium-long (7-21 days) macerations, was studied with spectrophotometric methods, high-performance liquid chromatography (HPLC), and three different antioxidant assays (2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS), ferric reducing antioxidant power (FRAP) and 2,2 diphenyl-1-picrylhydrazyl (DPPH)). The total polyphenolic content (gallic acid equivalent (GAE)) of the seeds sampled after short macerations ranged between 24.5 and 60.1 mg/g dry weight (DW), and it dropped to 20.0-37.5 mg/g DW after medium-long macerations. The polyphenolic profile of the shortly macerated seeds was related to the varietal characteristics, while, after longer macerations, the influence of the maceration length prevailed on the cultivar effect. The multiple in vitro antioxidant activity tests (ABTS, FRAP and DPPH), although based on different mechanisms capable of highlighting behavioral differences between the different polyphenolic compounds, were highly correlated with each other and with the polyphenolic parameters; the qualitative differences between the matrices in the polyphenolic profile were probably less important than the quantitative differences in the polyphenolic content. The relations with the polyphenolic content were linear, except for the Efficient Concentration (EC20) parameter, whose relation was better described by a hyperbolic equation.</div></summary> <author><name>Mousecrib6</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Selfsupported_Ni3S2Ni2PMoS2_heterostructures_about_nickel_foam_to_have_an_exceptional_o2_development_impulse_along_with_successful_overall_h2o_busting&diff=3298537&oldid=0</id> <title>Selfsupported Ni3S2Ni2PMoS2 heterostructures about nickel foam to have an exceptional o2 development impulse along with successful overall h2o busting</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Selfsupported_Ni3S2Ni2PMoS2_heterostructures_about_nickel_foam_to_have_an_exceptional_o2_development_impulse_along_with_successful_overall_h2o_busting&diff=3298537&oldid=0"/> <updated>2025-06-03T10:20:22Z</updated> <summary type="html"><p>Created page with &quot;ate of LPN and decrease OT, WIT, and EBL.&lt;br /&gt;&lt;br /&gt; This article seeks to clarify and define the concept of tremors.&lt;br /&gt;&lt;br /&gt; The Walker &amp; Avant (2005) concept analys...&quot;</p><p><b>New page</b></p><div>ate of LPN and decrease OT, WIT, and EBL.&lt;br /&gt;&lt;br /&gt; This article seeks to clarify and define the concept of tremors.&lt;br /&gt;&lt;br /&gt; The Walker &amp;amp; Avant (2005) concept analysis method was followed.&lt;br /&gt;&lt;br /&gt; A search of PubMed, Academic Search Complete, CINAHL, ERIC, Google and Google Scholar was performed.&lt;br /&gt;&lt;br /&gt; Through this process, uses of the concept were assessed including definitions and categories of tremors. Defining attributes were found to include &quot;movement disorder,&quot; &quot;shaking motions,&quot; &quot;involuntary,&quot; &quot;oscillatory,&quot; &quot;rhythmic,&quot; &quot;not painful or life threatening,&quot; &quot;always present but variable&quot; and &quot;can sometimes be repressed.&quot; We identified two model cases and a borderline case, antecedents, consequences and empirical referents (including measurement tools) of tremors.&lt;br /&gt;&lt;br /&gt; The concept analysis process has clarified and illuminated an operational definition of tremors that tremors are a movement disorder characterized by shaking motions that are involuntary, oscillatory, rhythmic, non-painful, always present although vary in severity, and can be repressed by changing posture or going into a rest position.&lt;br /&gt;&lt;br /&gt;The concept analysis process has clarified and illuminated an operational definition of tremors that tremors are a movement disorder characterized by shaking motions that are involuntary, oscillatory, rhythmic, non-painful, always present although vary in severity, and can be repressed by changing posture or going into a rest position.&lt;br /&gt;&lt;br /&gt; This study aimed to determine the potential association between the dental diseases and self-reported history of stroke in the United States based on data from the Third National Health and Nutrition Examination Survey (NHANES III).&lt;br /&gt;&lt;br /&gt; Data were extracted from NHANES III. Dental variables were carious tooth surfaces, number of missing teeth, gingival bleeding, and periodontal pockets. Multiple logistic regression modeling was used to estimate the effect of these dental diseases on the self-reported history of stroke with intent to adjust for the other potential determinants age, sex, race, marital status, health insurance, education, exercise, body mass index, smoking, alcohol, hypertension, high serum cholesterol, and diabetes.&lt;br /&gt;&lt;br /&gt; Number of missing teeth was found to be significantly associated with the self-reported history of stroke. Associations between the self-reported history of stroke and caries, gingival bleeding, or periodontal pockets were not statistically significant.&lt;br /&gt;&lt;br /&gt; Number of missing teeth was an independent determinant of the self-reported history of stroke.&lt;br /&gt;&lt;br /&gt;Number of missing teeth was an independent determinant of the self-reported history of stroke.Spatial visualization, the ability to mentally rotate 3D images, plays a significant role in anatomy education. This study examines the impact of technical drawing exercises on the improvement of spatial visualization and anatomy education in a Neuroscience course. First-year medical students (n = 84) were randomly allocated into a control group (n = 41) or art-training group (n = 43). Variables including self-reported artistic drawing ability, previous technical drawing experience, or previous anatomy laboratory exposure were gathered. Participants who self-identified as artistic individuals were equally distributed between the two groups. Students in the art-training group attended four one-hour sessions to solve technical drawing worksheets. All participants completed two Mental Rotations Tests (MRT), which were used to assess spatial visualization. Data were also collected from two neuroscience written examinations and an anatomical &quot;tag test&quot; practical examination. Participants in the art-training and control groups improved on the MRT. The mean of written examination two was significantly higher (P = 0.007) in the art-training group (12.95) than the control group (11.48), and higher (P = 0.027) in those without technical drawing experience (12.44) than those with (11.00). The mean of the anatomical practical was significantly higher (P = 0.010) in those without artistic ability (46.24) than those with (42.00). These results suggest that completing technical drawing worksheets may aid in solving anatomy-based written examination questions on complex brain regions, but further research is needed to determine its implication on anatomy practical scores. These results propose a simple method of improving spatial visualization in anatomy education.&lt;br /&gt;&lt;br /&gt; This systematic review evaluated the evidence for the effectiveness of Photodynamic therapy (PDT) in treating oral fungal infections, as an alternative to conventional antifungal medications.&lt;br /&gt;&lt;br /&gt; Five randomized control trials (168 participants) comparing the treatment of oral fungal infections using met with our inclusion criteria. Clinical and microbiological improvement was assessed by random-effects meta-analysis. Methodological quality assessment and heterogeneity were performed using peer-reviewed criteria. PROSPERO registration CRD42017076.&lt;br /&gt;&lt;br /&gt; PDT showed statistically non-significant increased clinical efficacy (risk ratio (RR) = 1.47 [95% confidence interval (CI), 0.68; 3.17]; three studies, n = 108 participants, I&lt;br /&gt;&lt;br /&gt; = 50%) and mycological efficacy (mean difference (MD) = 0.54 [95%CI, -0.71; 1.79]; three studies, n = 100; I&lt;br /&gt;&lt;br /&gt; = 39%) at 30 days, as compared with conventional antifungal therapy. Lack of standardization of treatment parameters and variability in the assessment of outcomes was observed across the studies. All included studies had a moderate to low risk of bias.&lt;br /&gt;&lt;br /&gt; PDT showed comparable effectiveness at treating oral fungal infections, particularly denture stomatitis. The small number of studies in this review, small sample size and variability of methods and outcome measures across studies, highlight the need for more standardized studies with longer follow-up periods to enable recommendation of PDT as an alternative to conventional antifungal therapy.&lt;br /&gt;&lt;br /&gt;PDT showed comparable effectiveness at treating oral fungal infections, particularly denture stomatitis. [https://www.selleckchem.com/products/tp-1454.html see more] The small number of studies in this review, small sample size and variability of methods and outcome measures across studies, highlight the need for more standardized studies with longer follow-up periods to enable recommendation of PDT as an alternative to conventional antifungal therapy.</div></summary> <author><name>Creekticket2</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=What_About_Changing_My_Company_Name&diff=3298536&oldid=0</id> <title>What About Changing My Company Name</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=What_About_Changing_My_Company_Name&diff=3298536&oldid=0"/> <updated>2025-06-03T10:20:20Z</updated> <summary type="html"><p>Created page with &quot;Read all of the fine print before making a reservation for. Cheap airline tickets usually will not be altered or refunded issues arise. Cancellation insurance is really a wise...&quot;</p><p><b>New page</b></p><div>Read all of the fine print before making a reservation for. Cheap airline tickets usually will not be altered or refunded issues arise. Cancellation insurance is really a wise property.&lt;br /&gt;&lt;br /&gt;Contract. Preference sign the best document, you are entering Incorporate LLC ideal contract. Starting a business lets you sign and enter into contracts on the part of the business -- the contract will be between each other and your company, not you.&lt;br /&gt;&lt;br /&gt;First and foremost, the gender chart that you want to do? Do you have a special skill or trade that is capable of supporting you? The majority of fail recognize or recognize their marketable skills when they never give themselves the chance learn the way to capitalize at their God-given gifts.&lt;br /&gt;&lt;br /&gt;Can you handle a home based business? Some people lack the discipline to obtain work worn out a timely fashion precisely as it can be easy to get sucked into every day life -- including kids, friends, household chores, errands and relaxation time. Motivation is possibly the most important factor to consider before starting a business at home. Are you self encouraged? You won't have anyone looking over your shoulder or prodding you to obtain your work done.&lt;br /&gt;&lt;br /&gt;This will also help make a decision whether you will need to to do an C Corporation, an LLC or S corp. Choosing the LLc or S corp are the most prevalent and are right diverse business varieties.&lt;br /&gt;&lt;br /&gt;When looking to purchase a real estate in Bellaire, you will definitely not miss choice. The cost range may not be typical from $100,000 to into the millions dollars. Here, you understand beautiful seven or more bedroom homes nestled along with LLC incorporation small ranches.&lt;br /&gt;&lt;br /&gt;Trusting someone is very dangerous, especially a closer relative or long-time associate. Remember that this person is out for the money as well as the business. Difficulties when trying to works out that they're after difficult earned money and your small. Handshakes are a warm old custom, but that's what subjected to testing - a well used custom. Get anything you agree to in writing, and with non-interest witnesses. Just one stupid mistake can be priced at literally plenty of money.&lt;br /&gt;&lt;br /&gt;States are jealous each and every other. As soon as the IRS finally figured out how it would tax the limited liability company, all the other states immediately started passing laws that allowed LLCs become formed his or her states. A number [https://rentry.co/memnig6g registered agent services] of the laws even allowed one person to make up the entity. This caused immediate problems incredibly hard . of these single owner LLCs filed partnership tax returns.&lt;br /&gt;&lt;br /&gt;Let's consider California as an example. Under [https://postheaven.net/crocuscoast76/seized-car-auctions-and-starting-brand-new-business registered agent services near me] , an LLC is not technically needs to have a practical agreement or member long term contract. This is what many marketers are touting when they say the LLC is &quot;flexible.&quot; While these documents may not really technically required, you would be nuts to flex forward using the business without first getting them negotiated, completed and executed by all of the owners.</div></summary> <author><name>Degreepanda5</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Progression_of_any_multicoptercarried_total_atmosphere_trying_device_and_its_particular_programs_throughout_environment_scientific_studies&diff=3298535&oldid=0</id> <title>Progression of any multicoptercarried total atmosphere trying device and its particular programs throughout environment scientific studies</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Progression_of_any_multicoptercarried_total_atmosphere_trying_device_and_its_particular_programs_throughout_environment_scientific_studies&diff=3298535&oldid=0"/> <updated>2025-06-03T10:20:10Z</updated> <summary type="html"><p>Created page with &quot;In the last year, the Italian National Health Service as a whole and the Nephrology community have been severely challenged by the pandemic. It has been a dramatic stress test...&quot;</p><p><b>New page</b></p><div>In the last year, the Italian National Health Service as a whole and the Nephrology community have been severely challenged by the pandemic. It has been a dramatic stress test for the entire healthcare system, not only in Italy but worldwide. The general organization of our Nephrology units and our models of care were put under extreme pressure, and we had to quickly adopt unprecedented clinical practice recommendations and organizational models to overcome the impasse caused by the pandemic. The time has come to evaluate these new experiences, ask how we could have been better prepared and look for change. In this editorial, we outline a few proposals and suggestions for the future, weighing the information gathered in the 2018 Nephrology Census against the new organizational requirements imposed by the COVID-19 pandemic.&lt;br /&gt;&lt;br /&gt; In response to the COVID-19 pandemic, the American Center for Reproductive Medicine (ACRM) transitioned its annual training in assisted reproductive technology (ART) from a hands-on, laboratory-based training course to a fully online training endorsed by the American College of Embryology. Here we describe our experience and assess the quality of an online training format based on participant outcomes for the first three modules of a planned series of online ART training.&lt;br /&gt;&lt;br /&gt; These modules included manual semen analysis, sperm morphology and ancillary semen tests (testing for leukocytospermia, sperm vitality, and anti-sperm antibody screening). The virtual format consisted of lecture presentations featuring laboratory protocols with corresponding video demonstrations of routine techniques and best practices. Practical scenarios, troubleshooting, and clinical interpretation of laboratory results were also discussed. At the end of each module, an optional multiple choice question test was held as a prerequisite to obtain certification on the topics presented. Course quality was assessed using participant responses collected via online surveys.&lt;br /&gt;&lt;br /&gt; The digital delivery methods used were found to have largely or completely met the participants' expectations for all questions (&amp;gt;85%). [https://www.selleckchem.com/products/tauroursodeoxycholic-acid.html Tauroursodeoxycholic] The majority (&amp;gt;87%) of the participants either strongly agreed or agreed that the course content was well-structured with appropriate depth, and that their overall expectations of the course had been met.&lt;br /&gt;&lt;br /&gt; This training format appears to be a realistic teaching option to freely share highly specialized expertise and technical knowledge with participants from anywhere in the world with varying levels of competency or experience.&lt;br /&gt;&lt;br /&gt;This training format appears to be a realistic teaching option to freely share highly specialized expertise and technical knowledge with participants from anywhere in the world with varying levels of competency or experience.Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures are conducted according to the World Health Organization (WHO) guidelines, semen analysis and especially sperm morphology assessment is very difficult to standardize and obtain reproducible results. This is mainly due to the highly subjective nature of their evaluation. ICSI is the choice of treatment when sperm morphology is severely abnormal (teratozoospermic). Hence, the standardization of laboratory protocols for sperm morphology evaluation represents a fundamental step to ensure reliable, accurate and consistent laboratory results that avoid misdiagnoses and inadequate treatment of the infertile patient. This article aims to promote standardized laboratory procedures for an accurate evaluation of sperm morphology, including the establishment of quality control and quality assurance policies. Additionally, the clinical importance of sperm morphology results in assisted reproductive outcomes is discussed, along with the clinical management of teratozoospermic patients.The objectives of this study were to assess the effects of ginseng on erectile dysfunction. We searched multiple electronic databases from their inceptions to 30 January 2021 without restrictions by language. We included randomized or quasirandomized controlled trials that evaluated the use of any type of ginseng as a treatment for erectile dysfunction compared to placebo or conventional treatment. The authors independently screened the literature, extracted data, assessed risk of bias, and rated the certainty of evidence (CoE) according to the GRADE approach. We included nine studies, and all compared ginseng to placebo. Ginseng appears to have a trivial effect on erectile dysfunction when compared to placebo based on the Erectile Function Domain of the International Index of Erectile Function (IIEF)-15 instrument (mean difference [MD] 3.52, 95% confidence interval [CI] 1.79 to 5.25; I²=0%; 3 studies; low CoE). Ginseng may have little to no effect on adverse events compared to placebo (risk ratio [RR] 1.45, 95% CI 0.69 to 3.03; I²=0%; 7 studies; low CoE). While ginseng may improve men's self-reported ability to have intercourse (RR 2.55, 95% CI 1.76 to 3.69; I²=23%; 6 studies; low CoE), it may have a trivial effect on men's satisfaction with intercourse based on the Intercourse Satisfaction Domain of the IIEF-15 (MD 1.19, 95% CI 0.41 to 1.97; I²=0%; 3 studies; low CoE). No study reported quality of life as an outcome.&lt;br /&gt;&lt;br /&gt; To evaluate changing trends in relation to the sexual debut age and socioeconomic status (SES) in Korea.&lt;br /&gt;&lt;br /&gt; The Korean Internet Sexuality Survey (KISS) was conducted for in 2004, 2006, 2014, and 2016. We sent emails and surveyed people registered at an Internet survey agency. To determine the changing trends in sexual debut age, we collected and compared the responses of females in their 20s in 2004 (n=253) and 2014 (n=131) and collected and compared the responses of males in their 20s in 2006 (n=87) and 2016 (n=200).&lt;br /&gt;&lt;br /&gt; In females, SES factors such as occupation, income, and academic background were not related to early sexual debut age. In the 2006 male study, early sexual debut age was associated with occupation, income, and academic background. However, in the 2016 male study, participants' academic background was the only significant factor about early sexual debut age. In both the male and female studies, early sexual debut age was related to a higher number of sexual partners in life. Also, in both female cohorts (2004 and 2014), the number of pregnancies and the incidents of sexual abuse experienced were higher in the early sexual debut groups.</div></summary> <author><name>Authorharbor43</name></author> </entry> <entry> <id>https://humanlove.stream/wiki/User:Goldwin678</id> <title>User:Goldwin678</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/wiki/User:Goldwin678"/> <updated>2025-06-03T10:20:05Z</updated> <summary type="html"><p>User account <a href="/index.php?title=User:Goldwin678&amp;action=edit&amp;redlink=1" class="new mw-userlink" title="User:Goldwin678 (page does not exist)"><bdi>Goldwin678</bdi></a> was created</p></summary> <author><name>Goldwin678</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=Thyroid_Cancers_Risks_in_Children_using_Hypothyroid_Nodules_A_new_OneCenter_Examine&diff=3298534&oldid=0</id> <title>Thyroid Cancers Risks in Children using Hypothyroid Nodules A new OneCenter Examine</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=Thyroid_Cancers_Risks_in_Children_using_Hypothyroid_Nodules_A_new_OneCenter_Examine&diff=3298534&oldid=0"/> <updated>2025-06-03T10:20:01Z</updated> <summary type="html"><p>Created page with &quot;This article offers a feminist reflection written as a nocturnal stream of consciousness exposing the embodied, emotional and professional experience of living and working dur...&quot;</p><p><b>New page</b></p><div>This article offers a feminist reflection written as a nocturnal stream of consciousness exposing the embodied, emotional and professional experience of living and working during a pandemic outbreak. Framed within a feminist approach, this personal narrative provides an example of the effects of such unexpected and unprecedented circumstances on personal and professional academic lives. Developed during the first stage of the (inter)national coronavirus pandemic, my reflections address issues of privilege; emotional labour; the virtual invasion of the home space within the current increasingly ambiguous space of 'the workplace'; workload; and wellbeing. Further, I consider how the newly enforced flexible work measures based on online tools have turned current work-life dynamics into a 'Never-ending Shift'.The COVID-19 disease continues to cause unparalleled disruption to life and the economy world over. This paper is the second in what will be an ongoing series of analyses of a longitudinal travel and activity survey. In this paper we examine data collected over a period of late May to early June in Australia, following four-to-six weeks of relatively flat new cases in COVID-19 after the initial nationwide outbreak, as many state jurisdictions have begun to slowly ease restrictions designed to limit the spread of the SARS-CoV-2 virus. We find that during this period, travel activity has started to slowly return, in particular by private car, and in particular for the purposes of shopping and social or recreational activities. Respondents indicate comfort with the idea of meeting friends or returning to shops, so authorities need to be aware of potential erosion of social distancing and appropriate COVID-safe behaviour in this regard. There is still a concern about using public transport, though it has diminished noticeably since the first wave of data collection. [https://www.selleckchem.com/products/etomoxir-na-salt.html selleck kinase inhibitor] We see that working from home continues to be an important strategy in reducing travel and pressure on constrained transport networks, and a policy measure that if carried over to a post-pandemic world, will be an important step towards a more sustainable transport future. We find that work from home has been a generally positive experience with a significant number of respondents liking to work from home moving forward, with varying degrees of employer support, at a level above those seen before COVID-19. Thus, any investment to capitalise on current levels of work from home should be viewed as an investment in transport.The slowdown of economy and widening of domestic imbalances in China bothers economists and politicians across the globe. We estimate the influence of a negative output shock in China on a number of different economies. We concentrate on China's neighboring countries. We compare the results from the Global VAR model and from the Bayesian VAR models. Also using Bayesian model averaging we search for determinants of Chinese spillovers for the global economy. We find that spillovers are stronger to economies with less flexible exchange rates, a higher share of manufacturing in gross value added and to economies which are larger.This article projects business risk through deferent industrial scenarios in concentrated solar investments in the United Arab Emirates (UAE). Nationwide, the government seeks a sustainable solution through energy policy development and engagement of the stakeholders for clean energy generation at wider level in the long run. Support has been extended through various support schemes. In the current study, Monte Carlo simulations and net present value (NPV) risk are used to analyse the return on investment. A 5 MW concave solar panel project is evaluated. We have assessed the impact of local factors on profits through NPV. The study proposes that a higher NPV is expected if the concave solar panel project is financed 50% by Khalifa funding. The study also proposes a robust policy and highlights the opportunity of business profitability if the government subsidises land leasing with respect to each scenario. Additionally, the study also proposes a policy to maintain the interests of investors in the UAE.The Chinese government promotes the Belt and Road Initiative (BRI) as a global strategy for regional integration and infrastructure investment. With a projected US$1 trillion commitment from Chinese financial institutions, and at least 138 countries participating, the BRI is attracting intense debate. Yet most analysis to date focuses on broad drivers, risks, and opportunities, largely considered to be emanating from a coherent policy imposed by Beijing. In this special issue, we instead examine the BRI as a relational, contested process - a bundle of intertwined discourses, policies, and projects that sometimes align but are sometimes contradictory. We move beyond policy-level, macro-economic, and classic geopolitical analysis to study China's global investments &quot;from the ground&quot;. Our case studies reveal the BRI to be dynamic and unstable, rhetorically appropriated for different purposes that sometimes but do not always coalesce as a coherent geopolitical and geoeconomic strategy. The papers in this special issue provide one of the first collections of deep empirical work on the BRI and a useful approach for grounding China's role in globalization in the critical contexts of complex local realities.Outbreaks of emerging infectious diseases are occurring with increasing frequency and consequences, including wildlife diseases and zoonoses. Those have potentially long-lasting effects on human and wildlife populations, with inevitable direct and indirect effects on ecosystems. The intensifying emergence of infectious pathogens has many underlying reasons, all driven by the growing anthropogenic impact on nature. Intensifying pathogen emergence can be attributed to climate change, biodiversity loss, habitat degradation, and an increasing rate of wildlife-human contacts. All of these are caused by synergies between persisting intense poverty and a growing human population. Improved global management of the human-driven biological degradation and international dispersal processes that exacerbate those pandemic threats are now long overdue. It is vital that we act decisively in the aftermath of the COVID-19 crisis to radically change how we collectively manage the planet as a whole.</div></summary> <author><name>Pinkcoal73</name></author> </entry> <entry> <id>https://humanlove.stream/index.php?title=A_thorough_summary_of_your_complicated_partnership_among_epigenetics_bioactive_elements_most_cancers_along_with_aging&diff=3298533&oldid=0</id> <title>A thorough summary of your complicated partnership among epigenetics bioactive elements most cancers along with aging</title> <link rel="alternate" type="text/html" href="https://humanlove.stream/index.php?title=A_thorough_summary_of_your_complicated_partnership_among_epigenetics_bioactive_elements_most_cancers_along_with_aging&diff=3298533&oldid=0"/> <updated>2025-06-03T10:19:54Z</updated> <summary type="html"><p>Created page with &quot;Existing predictive outcomes models for type 2 diabetes developed and validated in historical European populations may not be applicable for East Asian populations due to diff...&quot;</p><p><b>New page</b></p><div>Existing predictive outcomes models for type 2 diabetes developed and validated in historical European populations may not be applicable for East Asian populations due to differences in the epidemiology and complications. Despite the continuum of risk across the spectrum of risk factor values, existing models are typically limited to diabetes alone and ignore the progression from prediabetes to diabetes. The objective of this study is to develop and externally validate a patient-level simulation model for prediabetes and type 2 diabetes in the East Asian population for predicting lifetime health outcomes.&lt;br /&gt;&lt;br /&gt; We developed a health outcomes model from a population-based cohort of individuals with prediabetes or type 2 diabetes Hong Kong Clinical Management System (CMS, 97,628 participants) from 2006 to 2017. The Chinese Hong Kong Integrated Modeling and Evaluation (CHIME) simulation model comprises of 13 risk equations to predict mortality, micro- and macrovascular complications, and development of diabetes. R of simulated cohorts derived from trial participants.&lt;br /&gt;&lt;br /&gt; Our study shows that the CHIME model is a new validated tool for predicting progression of diabetes and its outcomes, particularly among Chinese and East Asian populations that has been lacking thus far. The CHIME model can be used by health service planners and policy makers to develop population-level strategies, for example, setting HbA1c and lipid targets, to optimize health outcomes.&lt;br /&gt;&lt;br /&gt;Our study shows that the CHIME model is a new validated tool for predicting progression of diabetes and its outcomes, particularly among Chinese and East Asian populations that has been lacking thus far. The CHIME model can be used by health service planners and policy makers to develop population-level strategies, for example, setting HbA1c and lipid targets, to optimize health outcomes.&lt;br /&gt;&lt;br /&gt; The effects of long-term cigarette smoke exposure on pulmonary physiology and how those effects lead to reduced exercise capacity are not well established.&lt;br /&gt;&lt;br /&gt; We retrospectively analyzed the spirometry, single-breath gas transfer (DLCO), peripheral muscle strength, and maximum exercise capacity data in patients referred to McMaster University Medical Centre for cardiopulmonary exercise testing between 2000 and 2012.&lt;br /&gt;&lt;br /&gt; 29,441 subjects underwent CPET and had a recorded smoking history [58% male, mean age 51.1 years (S.D.±19.6), BMI 27.4 kg/m2(±5.8)]. 7081 (24%) were current or former smokers and were divided into 4 categories by packs years (mean ±S.D.) &amp;lt;10 (5.8±3.3), 10-20 (17.1±2.9), 20-30 (27.1±2.8), 30-40 (37.3±2.8), and &amp;gt;40 (53.9±12.8). Patients with greater cigarette smoke exposure had lower expiratory flow rates (FEV1, FEF50, FEF75, PEFR), DLCO, and maximum power output (MPO) during exercise. There was no association between smoke exposure and muscle strength. Modeling MPO (kpm/min) output as a function of demographic and physiologic variables showed that the data are well explained by muscle strength (kg), FEV1 (L), and DLCO (mmHg/min/mL) in similar magnitude (MPO = 42.7*Quads0.34*FEV10.34 * DLCO0.43; r = 0.84).&lt;br /&gt;&lt;br /&gt; Long-term cigarette smoke exposure is associated with small airway narrowing and impaired diffusion capacity but not with peripheral muscle weakness. [https://www.selleckchem.com/products/smi-4a.html selleck compound] The effects of smoking, age, and gender on maximum power output are mediated by reductions in FEV1, muscle strength and DLCO. Exercise capacity in smokers may benefit from therapies targeting all 3 variables.&lt;br /&gt;&lt;br /&gt;Long-term cigarette smoke exposure is associated with small airway narrowing and impaired diffusion capacity but not with peripheral muscle weakness. The effects of smoking, age, and gender on maximum power output are mediated by reductions in FEV1, muscle strength and DLCO. Exercise capacity in smokers may benefit from therapies targeting all 3 variables.To investigate the influence of bedding structure and different loading rates on the dynamic fracture characteristics and energy dissipation of Datong coal, a split Hopkinson bar was used to obtain the fracture characteristics of coal samples with different bedding angles. The process of crack initiation and propagation in Datong coal was recorded by the high-speed camera. The formula for the model I fracture toughness of the transversely isotropic material is obtained on the basis of the finite element method (FEM) together with the J-integral. By comparing the incident energy, absorbed energy, fracture energy and residual kinetic energy of Datong coal samples under various impact speeds, the energy dissipation characteristics during the dynamic fracture process of coal considering the bedding structure is acquired. The experimental results indicate that the fracture pattern of notched semi-circular bending (NSCB) Datong coal is tensile failure. After splitting into two parts, the coal sample rotates approxies.The burden of STIs is particularly high in HIV-infected MSM patients. A recent increase in STIs prevalence has been noticed in the US and western European countries. We aim to assess trends in asymptomatic STIs following the publication of recommendations for STIs screening, i.e. Chlamydia (CT) and gonorrhea (NG). Seventeen centers located in the Paris area participated in the study. All asymptomatic HIV-infected MSM patients attending a follow up consultation were proposed to participated in the study. Asymptomatic patients were included over 2 periods period 1 from April to December 2015 and period 2 from September to December 2017. Etiologic diagnosis of STIs including hepatitis B, C, syphilis, was performed using a serological test, including a non-treponemal titer with a confirmatory treponemal assay for syphilis. CT and NG were screened using a nucleic acid amplification test (NAATs) on 3 anatomical sites, i.e. urine, rectal and pharyngeal. Overall, 781 patients were included 490 and 291 in periods 1 and 2 respectively. Asymptomatic CT, NG, and syphilis were diagnosed in 7.5%, 4.8% and, 4.2% respectively. The rate of patients having a multisite asymptomatic infection was 10.2% and 21.1% for CT and NG respectively. The most frequently involved anatomical sites for CT and NG asymptomatic infections were anorectal (66.1% and 55.2% respectively) and pharyngeal (47.4% and 60.5% respectively). CT and NG asymptomatic infection increased by 1.3- and 2-fold respectively between the two periods while syphilis decreased by 3 folds. Our results encourage to reconsider multisite screening for CT and NG in asymptomatic HIV positive MSM as the yield of screening urinary samples only might be low. Despite the more systematic STI screening of asymptomatic HIV positive MSM the prevalence of STI is increasing in MSM in France. Therefore, this strategy has not led to alter CT and NG transmission. The decrease of syphilis might involve self-medication by doxycycline, and the intensification of syphilis screening.</div></summary> <author><name>Polofork7</name></author> </entry> </feed>If you would like to create a banner that links to this page (i.e. this validation result), do the following:
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